Prevalence Of Hypertension And Associated Variables In PaidWorkers In Ilorin, Nigeria

The enormous burden of hypertension worldwide and in Africa, informed the decision to measure the blood pressure pattern in salaried workers in Ilorin,Nigeria.These were selected, as they resemble closely those that are likely to be affected bywestern style living. It was a cross-sectional study that involved staff of both government and a private organisation in Ilorin, Nigeria. Two hundred and eighty one subjects, comprising of 211 males and 70 females were recruited into the study. Systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI) and fasting plasma glucose (FPG)were determined. The prevalence of hypertension was 27.1% in the population, being 28.4% in males and 22.9% in females. Mean SBP and DBP were significantly higher in females (SBP; 139.59mmHg ± 20.84, DBP; 86.92mmHg ± 10.96) than inmales (SBP; 127.39mmHg ± 19.55,DBP; 82.16mmHg). P< 0.05.The prevalence of hypertension increasedwith age and BMI.Age was correlated to SBP, (r = 0.355, P< 0.01)DBP, (r = 0.322, P < 0.01) and BMI (r = 0.143, P < 0.05). Obesity prevalence was 13.2% consisting of males (5.3%) and females (7.8%). Prevalence of diabetesmellituswas similar in both sexes at 1.5%. There is a high prevalence of hypertension among salary earners in Ilorin, Nigeria and this is commoner among males. The degree of increase in BP is worse in female workers. Obesity is on the upward climb in our society and should be addressed early in order to curtail its associatedmorbidities. Keywords: Hypertension, Paid Workers,Nigeria. Nigerian Journal of Clinical Practice Vol. 11 (4) 2008: pp. 342-34

Effects of aqueous extract of Ocimum gratissimum on haematological parameters of Wistar rats

The effect of aqueous extract of Ocimum gratissimum on hematological parameters of Wister rats was studied. Twenty five rats with weight ranging between 100-160g were used. The rats were divided into five groups; with group one as the control group. Increasing doses (0.2, 0.4,0.8, 1.6g kg-1 body weight) of the extract were administered orally to the other four groups for a period of four weeks. Significant (P< 0.05) decreases in the level of hemoglobin (Hb), packed cell volume (PCV), red blood cells (RBC), white blood cells (WBC) and other hematological parameters were observed

Serum zinc levels as a predictor of clinical features and outcome of paediatric acute lower respiratory infections in Nigeria

Background: Malnutrition, especially macronutrient deficiency, has been shown to be interrelated with ALRI-related morbidity and mortality. However the import of zinc deficiency has only recently become the focus of research attention.Objective: The current study was carried out in Ilorin, Kwara State, Nigeria to determine the relationship between serum zinc levels, clinical features and outcome in hospitalized children with acute lower respiratory infections(ALRI).Method: A descriptive crosssectional hospital-based study involving 120 children aged two months to five years with ALRI. Socio-demographic, clinical and laboratory data were obtained. The serum zinc was analyzed with a Jenway™ spectrophotometer after initial preparation with theQuantiChrom™ zinc assay kit.Results: Children with tachypnoea and crepitations had significantly lower mean serum zinc levels compared to the corresponding values in those without these features (each p&lt;0.05). Significantly higher mean serum zinc level was recorded in children with grunting respiration compared with thosewithout grunting (p=0.028). Agerelated tachypnoea, grunting, and crepitations remained significant (each p&lt;0.05) following a linear  regression analysis. The mean serum zinc level in children with multiple complications was significantly lower than the corresponding level recorded in children who had one complication, p=0.020. No significant differencewas found between the mean serum zinc level of the children who were discharged compared with the corresponding level recorded in those that died, p=0.589.Conclusion: The presence of crepitations had the strongest clinical association with a low serum zinc level. Children managed for ALRI would benefit from post-treatment zinc supplements and appropriate zinc-rich sources of food at discharge.Keywords: Children zinc respiratory infection

Gynecological laparoscopic surgeries: A 4‑year audit at the University of Ilorin Teaching Hospital, Nigeria

Background: In addition to a shorter hospital stay and better cosmetic results, laparoscopic surgery also offers patients fewer postoperative complications compared to conventional open gynecological surgeries. With expertise and better facilities, it has come to stay as an alternative surgical approach to gynecological diagnosis and treatment.Aims and Objectives: The aim of this study was to assess the indications, intraoperative findings, and types of laparoscopic surgeries performed at the University of Ilorin Teaching Hospital, Ilorin.Materials and Methods: A retrospective observational study of 150 patients who underwent laparoscopic procedures between January 1, 2012 and December 31, 2015, at the Assisted Reproduction Technology (ART) unit of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria.Results: Within the period of our review, there were 1,256 gynecological operations and 150 laparoscopies, thus giving a period prevalence of 11.2%. The patients were aged 20–59 years with a mean age of 32.1 ± 3.9 years. Of the 150 laparoscopies, 30 (20%) had diagnostic laparoscopies while 120 (80%) had therapeutic laparoscopies. Of the 30 patients who had diagnostic laparoscopies, 5 (16.7%) presented with primary infertility and 12 (40%) with secondary infertility. The commonest indication for therapeutic laparoscopy was clomiphene‑resistant polycystic ovary syndrome (PCOS) and was found in 81 (67.5%). One (0.7%) was converted to open surgery due to technical difficulties. There was a case of iatrogenic sigmoid colon injury and no mortality recorded.Conclusion: Laparoscopic surgery offers patients a novel choice of intervention that affords establishing definitive diagnosis, shorter hospital stay, better cosmetics, and reduced morbidities/mortalities compared to open gynecological surgeries.Key words: Gynecological; Ilorin; laparoscopy; Nigeria

Serial pathologic fractures of five long bones on four separate occasions in a patient with primary hyperparathyroidism, challenges of management in a developing country: a case report

Multiple pathologic fractures secondary to parathyroid adenoma is rarely recognized and reported in the tropics. Inadequate evaluation causes worsened disability and increased psychological stress. We present a 27-year-old Nigerian male student with recurrent unexplained pathological fractures of the long bones. Primary Hyperparathyroidism was later diagnosed and he benefited from a unilateral parathyroidectomy. Primary hyperparathyroidism secondary to parathyroid adenoma is difficult to diagnose and needs a high index of suspicion. Surgery and good  postoperative biochemical control of serum calcium produce satisfying outcomesKey words: Pathologic fractures, parathyroid adenoma, Primary Hyperparathyroidism, serum calcium, surger

Effects of Cigarette Smoking on Urinary Testosterone Excretion in Men

Cigarette smoking is a major public health problem that is associated with high morbidity and mortality. This study was designed to investigate the relationship between cigarette smoking and concentration of testosterone in the urine. Forty young men age between 23 to 31 years were used for this study. The subjects were divided into two groups of 20 controls (noncigarette smoker) and 20 experimental groups (cigarette smoker). 5ml of mid-stream urine was collected from each subject at 0700 hour and urine testosterone concentration was estimated using enzyme immunoassay method. The result showed that the urinary testosterone concentration of non-cigarette smokers was 4.35±0.52 ng/ml, while the concentration in cigarette smokers was 2.81±0.38 ng/ml with

Pregnancy Outcomes Following Assisted Reproduction Technologies For Infertile Women At A Public Health Institution In Nigeria

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Relationship Between Glycaemic Control And Hypertension In Nigerian Type II Diabetic Patients Attending The Medical Outpatient Clinics, U.I.T.H. Ilorin

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Electrolyte Profile of Epileptic Patients on Carbamazepine Monotherapy

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L-Tryptophan Reduces Creatinine Clearance In Alloxan-Induced Diabetic Rats

Previous studies on type I diabetes have shown that toxic effects by free radicals are involved in the damage to the renal system. Tryptophan is known to have antioxidant effect and is a precursor of melatonin which is a powerful antioxidant. The aim of this study was to evaluate the effectiveness of tryptophan in mitigating renal damage in type I diabetic rats. Eighteen male Sprague-Dawley rats were divided into three experimental groups: Control, Untreated Diabetic and Tryptophan-treated Diabetic. Weight change, fasting blood glucose, urinary albumin excretion and creatinine clearance were measured at the beginning and at the end of the study. It was found that tryptophan treatment reduced the urinary albumin excretion and creatinine clearance in diabetic rats (p&lt;0.05). However, the urinary albumin excretion and creatinine clearance were still higher than in the control rats. Treatment with tryptophan slightly reduced the fasting blood glucose in rats, this was however not statistically significant. There was an increase in weight in rats treated with tryptophan compared to the untreated diabetic rats, however, this was not statistically significant. It was therefore concluded that oral tryptophan treatment might improve renal disturbances in early type I diabetes mellitus.The Tropical Journal of Health Sciences Vol 19 No 1 (January 2012