The Way We Are: 100 Plain Dealer Op-Eds

The book contains 100 op-ed articles submitted by Thomas Bier to the Plain Dealer and published between 1977 and 2022. Most of the articles concern a current event or issue in the city of Cleveland and/or communities in Northeast Ohio. 100 articles involve 100 topics, varying from local history, to the effect of public policy on communities, to where to locate a new baseball stadium.https://engagedscholarship.csuohio.edu/clevmembks/1066/thumbnail.jp

Housing Dynamics in Northeast Ohio: Setting the Stage for Resurgence

The book presents an overview of regional housing dynamics and consequent impacts in Northeast Ohio since the 1940s. Focus is on the city of Cleveland and its host county. Dynamics are examined in terms of supply and demand, population movement, lifespan of buildings, and the influence of government on the choices people have when considering where to live. Impacts include housing decline and abandonment, change in property value, and urban sprawl. Recommendations, centered on tax-base growth sharing, are presented for altering existing dynamics to support Northeast Ohio’s resurgence.https://engagedscholarship.csuohio.edu/msl_ae_ebooks/1003/thumbnail.jp

Liquid-liquid interfacial tension of electrolyte solutions

It is theoretically shown that the excess liquid-liquid interfacial tension between two electrolyte solutions as a function of the ionic strength I behaves asymptotically as O(- I^0.5) for small I and as O(+- I) for large I. The former regime is dominated by the electrostatic potential due to an unequal partitioning of ions between the two liquids whereas the latter regime is related to a finite interfacial thickness. The crossover between the two asymptotic regimes depends sensitively on material parameters suggesting that, depending on the actual system under investigation, the experimentally accessible range of ionic strengths can correspond to either the small or the large ionic strength regime. In the limiting case of a liquid-gas surface where ion partitioning is absent, the image chage interaction can dominate the surface tension for small ionic strength I such that an Onsager-Samaras limiting law O(- I ln(I)) is expected. The proposed picture is consistent with more elaborate models and published measurements.Comment: Accepted for publication in Physical Review Letter

We Don't Need Another Hero? The Impact of "Heroes" on Software Development

A software project has "Hero Developers" when 80% of contributions are delivered by 20% of the developers. Are such heroes a good idea? Are too many heroes bad for software quality? Is it better to have more/less heroes for different kinds of projects? To answer these questions, we studied 661 open source projects from Public open source software (OSS) Github and 171 projects from an Enterprise Github. We find that hero projects are very common. In fact, as projects grow in size, nearly all project become hero projects. These findings motivated us to look more closely at the effects of heroes on software development. Analysis shows that the frequency to close issues and bugs are not significantly affected by the presence of project type (Public or Enterprise). Similarly, the time needed to resolve an issue/bug/enhancement is not affected by heroes or project type. This is a surprising result since, before looking at the data, we expected that increasing heroes on a project will slow down howfast that project reacts to change. However, we do find a statistically significant association between heroes, project types, and enhancement resolution rates. Heroes do not affect enhancement resolution rates in Public projects. However, in Enterprise projects, the more heroes increase the rate at which project complete enhancements. In summary, our empirical results call for a revision of a long-held truism in software engineering. Software heroes are far more common and valuable than suggested by the literature, particularly for medium to large Enterprise developments. Organizations should reflect on better ways to find and retain more of these heroesComment: 8 pages + 1 references, Accepted to International conference on Software Engineering - Software Engineering in Practice, 201

Organic syntheses employing supercritical carbon dioxide as a reaction solvent

Chemical reactions are readily carried out using supercritical carbon dioxide as the reaction medium. Supercritical carbon dioxide is of special value as a reaction medium in reactions for synthesizing polypeptides, for sequencing polypeptides, or for amino acid analysis

Organic syntheses employing supercritical carbon dioxide as a reaction solvent

Chemical reactions are readily carried out using supercritical carbon dioxide as the reaction medium. Supercritical carbon dioxide is of special value as a reaction medium in reactions for synthesizing polypeptides, for sequencing polypeptides, or for amino acid analysis

Feasiblity study for a 34 GHz (Ka band) gyroamplifier

The feasibility of using a gyroklystron power tube as the final amplifier in a 400 kW CW 34 GHz transmitter on the Goldstone Antenna is investigated. A conceptual design of the gyroklystron and the transmission line connecting it with the antenna feed horn is presented. The performance characteristics of the tube and transmission line are compared to the transmitter requirements for a deep space radar system. Areas of technical risk for a follow-on hardware development program for the gyroklystron amplifier and overmoded transmission line components are discussed

Temporary Disruption of the Retinal Basal Lamina and Its Effect on Retinal Histogenesis

AbstractAn experimental paradigm was devised to remove the retinal basal lamina for defined periods of development: the basal lamina was dissolved by injecting collagenase into the vitreous of embryonic chick eyes, and its regeneration was induced by a chase with mouse laminin-1 and α2-macroglobulin. The laminin-1 was essential in reconstituting a new basal lamina and could not be replaced by laminin-2 or collagen IV, whereas the macroglobulin served as a collagenase inhibitor that did not directly contribute to basal lamina regeneration. The regeneration occurred within 6 h after the laminin-1 chase by forming a morphologically complete basal lamina that included all known basal lamina proteins from chick embryos, such as laminin-1, nidogen-1, collagens IV and XVIII, perlecan, and agrin. The temporary absence of the basal lamina had dramatic effects on retinal histogenesis, such as an irreversible retraction of the endfeet of the neuroepithelial cells from the vitreal surface of the retina, the formation of a disorganized ganglion cell layer with an increase in ganglion cells by 30%, and the appearance of multiple retinal ectopias. Finally, basal lamina regeneration was associated with aberrant axons failing to correctly enter the optic nerve. The present data demonstrate that a transient disruption of the basal lamina leads to dramatic and probably irreversible aberrations in the histogenesis in the developing central nervous system

Stability of additive-free water-in-oil emulsions

We calculate ion distributions near a planar oil-water interface within non-linear Poisson-Boltzmann theory, taking into account the Born self-energy of the ions in the two media. For unequal self-energies of cations and anions, a spontaneous charge separation is found such that the water and oil phase become oppositely charged, in slabs with a typical thickness of the Debye screening length in the two media. From the analytical solutions, the corresponding interfacial charge density and the contribution to the interfacial tension is derived, together with an estimate for the Yukawa-potential between two spherical water droplets in oil. The parameter regime is explored where the plasma coupling parameter exceeds the crystallization threshold, i.e. where the droplets are expected to form crystalline structures due to a strong Yukawa repulsion, as recently observed experimentally. Extensions of the theory that we discuss briefly include numerical calculations on spherical water droplets in oil, and analytical calculations of the linear PB-equation for a finite oil-water interfacial width.Comment: 9 pages, 4 figures, accepted by JPCM for proceedings of LMC

DNA-nanostructure-assembly by sequential spotting

<p>Abstract</p> <p>Background</p> <p>The ability to create nanostructures with biomolecules is one of the key elements in nanobiotechnology. One of the problems is the expensive and mostly custom made equipment which is needed for their development. We intended to reduce material costs and aimed at miniaturization of the necessary tools that are essential for nanofabrication. Thus we combined the capabilities of molecular ink lithography with DNA-self-assembling capabilities to arrange DNA in an independent array which allows addressing molecules in nanoscale dimensions.</p> <p>Results</p> <p>For the construction of DNA based nanostructures a method is presented that allows an arrangement of DNA strands in such a way that they can form a grid that only depends on the spotted pattern of the anchor molecules. An atomic force microscope (AFM) has been used for molecular ink lithography to generate small spots. The sequential spotting process allows the immobilization of several different functional biomolecules with a single AFM-tip. This grid which delivers specific addresses for the prepared DNA-strand serves as a two-dimensional anchor to arrange the sequence according to the pattern. Once the DNA-nanoarray has been formed, it can be functionalized by PNA (peptide nucleic acid) to incorporate advanced structures.</p> <p>Conclusions</p> <p>The production of DNA-nanoarrays is a promising task for nanobiotechnology. The described method allows convenient and low cost preparation of nanoarrays. PNA can be used for complex functionalization purposes as well as a structural element.</p