Additional file 4: Figure S4. of HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail

HOXA7 promotes cell proliferation and tumor growth of liver cancer cell. (A) MTT assay of liver cancer cells with silent expression of HOXA7. (B) MTT assay of liver cancer cells with overexpression of HOXA7. (C) Tumor formation assay of liver cancer cells with silent expression of HOXA7. (D) Tumor formation assay of liver cancer cells with overexpression of HOXA7. **P < 0.01 based on the Student t test. Error bars, SD. The each number of replicates is 3. (JPG 3241 kb

Additional file 5: Figure S5. of HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail

HOXA7 promotes expression levels of EMT markers. (A) Western blot analysis of EMT markers in liver cancer cells with silent expression of HOXA7. (B) Western blot analysis of EMT markers in liver cancer cells with overexpression of HOXA7. (C) qRT-PCR analysis of EMT markers in liver cancer cells with silent expression of HOXA7. (D) qRT-PCR analysis of EMT markers in liver cancer cells with overexpression of HOXA7. P < 0.01 in panel C-F based on the Student t test. Error bars, SD. The each number of replicates is 3. (JPG 4138 kb

Additional file 1: Figure S1. of HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail

Ectopic HOXA7 expression was related with metastasis of liver cancer. (A) Analysis of HOXA7 levels in noncancerous and tumorous tissues. (B) Analysis of HOXA7 levels in non-metastatic and metastatic liver cancer tissues. P < 0.01 in panel A and B based on the Student t test. Error bars, SD. The each number of replicates is 3. (JPG 976 kb