Seismic amelioration of existing reinforced concrete buildings. Strategy to optimize the amount of reinforcement for joints

Most of the existing Reinforced Concrete (RC) buildings in Italy were built according to obsolete regulations that were not enough aware of issues related to seismic design so that they need to be upgraded by pursuing either amelioration or full seismic rehabilitation. In doing that, the first step is to figure out what is, based on the results of the initial analysis of the structure in its ante-operam version, the best overall dissipative mechanism that could be ob-tained by a number of suitable and economically convenient local interventions. The choice of the overall dissipative mechanism strongly affects the amount of reinforcement to be adopted for the beam-column joints. For new buildings, the current adopted capacity design philosophy pursues an overall beam-sway mechanism in which plastic hinges first form in beams and at last at the base of the columns. On the contrary,for existing ones, often very irregular and gravity-load-dominated, pursuing such overall mechanism may result either uneconomic or even extremely difficult to implement due to the amount of reinforcement to be inserted in the joints. In such cases, an overall dissipative mechanism allowing, at some extent, columns flex-ural plasticizationshould be accepted and clearly identified in advance. Anyway,such ap-proach needs to be addressed properly in order to avoid the formation of column-sways at one story only that would result very dangerous due to the excessive demand of plastic rotations on the resulting hinges. This paper presents two simple models that may help the designer in deal-ing with the operations above. The formeris a model that allows to understand if, given the existing RC building case-study, either the beam-sway or a hybrid beam-column-sway mecha-nism should be conveniently pursued during the design of the retrofitting intervention. The lat-ter isa model that allows to design a hybrid beam-column-sway overall mechanism involving a suitable number of stories such as to guarantee a uniform and reasonable demand of plastic rotations in the involved columns

Iridoid glucosides from Pentas lanceolata (Forssk.) Deflers growing on the Island of Sardinia

The ethanolic extract of Pentas lanceolata (Forssk.) Deflers was investigated from a phytochemical point of view and in particular on the monoterpenoid glucosides content. Iridoid glucosides have a taxonomic relevance, e.g., asperuloside and its derivative are characteristic of the Rubioideae subfamily where this species is comprised. In the light of earliest phylogenetic molecular study which proposed to merge P. lanceolata in the Spermacoceae tribe, a phytochemical approach also becomes necessary for a correct classification of this species. A total of 12 compounds were identified in detail, ten of these are iridoid glucosides: asperuloside, asperulosidic acid, tudoside, E-uenfoside and Z-uenfoside previously identified in this genus; whereas, deacetyl-asperulosidic acid, ixoside, griselinoside, 6β,7β-epoxysplendoside were recognized here for the first time from P. lanceolata. Among the non-iridoidic compounds ursolic acid and d-xylose were identified

Automated Pruning for Deep Neural Network Compression

In this work we present a method to improve the pruning step of the current state-of-the-art methodology to compress neural networks. The novelty of the proposed pruning technique is in its differentiability, which allows pruning to be performed during the backpropagation phase of the network training. This enables an end-to-end learning and strongly reduces the training time. The technique is based on a family of differentiable pruning functions and a new regularizer specifically designed to enforce pruning. The experimental results show that the joint optimization of both the thresholds and the network weights permits to reach a higher compression rate, reducing the number of weights of the pruned network by a further 14% to 33% compared to the current state-of-the-art. Furthermore, we believe that this is the first study where the generalization capabilities in transfer learning tasks of the features extracted by a pruned network are analyzed. To achieve this goal, we show that the representations learned using the proposed pruning methodology maintain the same effectiveness and generality of those learned by the corresponding non-compressed network on a set of different recognition tasks.Comment: 8 pages, 5 figures. Published as a conference paper at ICPR 201

The luminosity evolution over the EQuiTemporal Surfaces in the prompt emission of Gamma-Ray Bursts

Due to the ultrarelativistic velocity of the expanding "fireshell" (Lorentz gamma factor \gamma \sim 10^2 - 10^3), photons emitted at the same time from the fireshell surface do not reach the observer at the same arrival time. In interpreting Gamma-Ray Bursts (GRBs) it is crucial to determine the properties of the EQuiTemporal Surfaces (EQTSs): the locus of points which are source of radiation reaching the observer at the same arrival time. In the current literature this analysis is performed only in the latest phases of the afterglow. Here we study the distribution of the GRB bolometric luminosity over the EQTSs, with special attention to the prompt emission phase. We analyze as well the temporal evolution of the EQTS apparent size in the sky. We use the analytic solutions of the equations of motion of the fireshell and the corresponding analytic expressions of the EQTSs which have been presented in recent works and which are valid for both the fully radiative and the adiabatic dynamics. We find the novel result that at the beginning of the prompt emission the most luminous regions of the EQTSs are the ones closest to the line of sight. On the contrary, in the late prompt emission and in the early afterglow phases the most luminous EQTS regions are the ones closest to the boundary of the visible region. This transition in the emitting region may lead to specific observational signatures, i.e. an anomalous spectral evolution, in the rising part or at the peak of the prompt emission. We find as well an expression for the apparent radius of the EQTS in the sky, valid in both the fully radiative and the adiabatic regimes. Such considerations are essential for the theoretical interpretation of the prompt emission phase of GRBs.Comment: 11 pages, 5 figures, in the Proceedings of the 1st Galileo-Xu GuangQi Meeting, October 26-30, 2009, Shangha

New developments in the synthesis of emicoron

This paper reports on the modification of two synthetic steps in the usual protocol used for obtaining EMICORON. EMICORON is a benzo[ghi]perylen-diimide, which was synthesized for the first time in our laboratory in 2012, and has shown to have in vivo antitumor activities that interferes with the tumor growth and development using a multi-target mechanism of action. The provided modifications, which involved the reaction times, the reaction conditions, and the work-up procedures, allowed the global yield of the process to be increased from 28% to about 40%. Thus, this new procedure may be more suitable for recovering higher amounts of EMICORON to be used in further preclinical studies

The combined automatic repeat request and rate control mechanism in S-band mobile interactive multimedia asynchronous return link - design background, parameter dimensioning and first experimental results

In the S-band mobile interactive multimedia specification, an asynchronous access using Enhanced Spread Spectrum Aloha random access has been defined for occasional messaging applications. This access scheme is complemented by a combined automatic repeat request and terminal rate control mechanism that is described in this paper. Furthermore, a queuing theory-based model is developed to describe the behaviour of the automatic repeat request mechanism, and performance results from the first proof-of-concept implementation are presented

Quantification of venous blood signal contribution to BOLD functional activation in the auditory cortex at 3 T

Most modern techniques for functional magnetic resonance imaging (fMRI) rely on blood-oxygen-level-dependent (BOLD) contrast as the basic principle for detecting neuronal activation. However, the measured BOLD effect depends on a transfer function related to neurophysiological changes accompanying electrical neural activation. The spatial accuracy and extension of the region of interest are determined by vascular effect, which introduces incertitude on real neuronal activation maps. Our efforts have been directed towards the development of a new methodology that is capable of combining morphological, vascular and functional information; obtaining new insight regarding foci of activation; and distinguishing the nature of activation on a pixel-by-pixel basis. Six healthy volunteers were studied in a parametric auditory functional experiment at 3 T; activation maps were overlaid on a high-resolution brain venography obtained through a novel technique. The BOLD signal intensities of vascular and nonvascular activated voxels were analyzed and compared: it was shown that nonvascular active voxels have lower values for signal peak (Pb10−7) and area (Pb10−8) with respect to vascular voxels. The analysis showed how venous blood influenced the measured BOLD signals, supplying a technique to filter possible venous artifacts that potentially can lead to misinterpretation of fMRI results. This methodology, although validated in the auditory cortex activation, maintains a general applicability to any cortical fMRI study, as the basic concepts on which it relies on are not limited to this cortical region. The results obtained in this study can represent the basis for new methodologies and tools that are capable of adding further characterization to the BOLD signal properties

Secondary metabolites with ecologic and medicinal implications in Anthemis cretica subsp. petraea from Majella National Park

Anthemis cretica subsp. petraea (Ten.) Greuter is a plant belonging to the Asteraceae family and endemic of central Italy. In this paper, the first analysisof the ethanolic fraction of samples collected in the Majella National Park is reported. Seven compounds were isolated and identified namely parthenolide (1), 9α-acetoxyparthenolide (2), tamarixetin (3), 7-hydroxycoumarin (4), 4'-hydroxyacetophenone (5), leucanthemitol (conduritol F) (6),and proto-quercitol (7). Isolation of the compounds was achieved by means ofcolumn chromatography (CC), while their identification was achieved through spectroscopic and spectrometric techniques. The presence of these compounds is of great relevance. Compounds 1 and 2 are chemosystematic markers of the family, thus confirming the correct botanical classification of the species. Conversely, compounds 3, 5,and 7 were identified for the first time in the species and, instead, confirm the tendency of endemic entities to develop characteristic metabolite patterns in respect to cosmopolite species. Moreover, the presence of compounds 6 and 7 has ecologic implications and may be linked to this taxon’s adaption to dry environments. The production of these osmolytes may, in fact, represent the reason why this species is able to survive in extreme conditions of aridity. Lastly, from a medicinal standpoint, the isolated compounds are endowed with interesting biological activities and may justify, on a molecular base, the widespread traditional uses of the Anthemis species, as well as a basis for the use ofthe subspecies petraea