10,721 research outputs found
Adversarial Sparse-View CBCT Artifact Reduction
We present an effective post-processing method to reduce the artifacts from
sparsely reconstructed cone-beam CT (CBCT) images. The proposed method is based
on the state-of-the-art, image-to-image generative models with a perceptual
loss as regulation. Unlike the traditional CT artifact-reduction approaches,
our method is trained in an adversarial fashion that yields more perceptually
realistic outputs while preserving the anatomical structures. To address the
streak artifacts that are inherently local and appear across various scales, we
further propose a novel discriminator architecture based on feature pyramid
networks and a differentially modulated focus map to induce the adversarial
training. Our experimental results show that the proposed method can greatly
correct the cone-beam artifacts from clinical CBCT images reconstructed using
1/3 projections, and outperforms strong baseline methods both quantitatively
and qualitatively
Using Health Information Technology to Prevent and Treat Diabetes
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140360/1/dia.2015.1507.pd
High-throughput screening of encapsulated islets using wide-field lens-free on-chip imaging
Islet microencapsulation is a promising solution to diabetes treatment, but
its quality control based on manual microscopic inspection is extremely
low-throughput, highly variable and laborious. This study presents a
high-throughput islet-encapsulation quality screening system based on lens-free
on-chip imaging with a wide field-of-view of 18.15 cm^2, which is more than 100
times larger than that of a lens-based optical microscope, enabling it to image
and analyze ~8,000 microcapsules in a single frame. Custom-written image
reconstruction and processing software provides the user with clinically
important information, such as microcapsule count, size, intactness, and
information on whether each capsule contains an islet. This high-throughput and
cost-effective platform can be useful for researchers to develop better
encapsulation protocols as well as perform quality control prior to
transplantation
Spectroscopic Evidence for the Specific Na+ and K+ Interactions with the Hydrogen-bonded Water Molecules at the Electrolyte Aqueous Solution Surfaces
Sum frequency generation vibrational spectra of the water molecules at the
NaF and KF aqueous solution surfaces showed significantly different spectral
features and different concentration dependence. This result is the first
direct observation of the cation effects of the simple alkali cations, which
have been believed to be depleted from the aqueous surface, on the hydrogen
bonding structure of the water molecules at the electrolyte solution surfaces.
These observations may provide important clue to understand the fundamental
phenomenon of ions at the air/water interface.Comment: 15 pages, 2 figure
Retrieval of phase memory in two independent atomic ensembles by Raman process
In spontaneous Raman process in atomic cell at high gain, both the Stokes
field and the accompanying collective atomic excitation (atomic spin wave) are
coherent. We find that, due to the spontaneous nature of the process, the
phases of the Stokes field and the atomic spin wave change randomly from one
realization to another but are anti-correlated. The phases of the atomic
ensembles are read out via another Raman process at a later time, thus
realizing phase memory in atoms. The observation of phase correlation between
the Stokes field and the collective atomic excitations is an important step
towards macroscopic EPR-type entanglement of continuous variables between light
and atoms
Recommended from our members
The cumulative effects of known susceptibility variants to predict primary biliary cirrhosis risk.
Multiple genetic variants influence the risk for development of primary biliary cirrhosis (PBC). To explore the cumulative effects of known susceptibility loci on risk, we utilized a weighted genetic risk score (wGRS) to evaluate whether genetic information can predict susceptibility. The wGRS was created using 26 known susceptibility loci and investigated in 1840 UK PBC and 5164 controls. Our data indicate that the wGRS was significantly different between PBC and controls (P=1.61E-142). Moreover, we assessed predictive performance of wGRS on disease status by calculating the area under the receiver operator characteristic curve. The area under curve for the purely genetic model was 0.72 and for gender plus genetic model was 0.82, with confidence limits substantially above random predictions. The risk of PBC using logistic regression was estimated after dividing individuals into quartiles. Individuals in the highest disclosed risk group demonstrated a substantially increased risk for PBC compared with the lowest risk group (odds ratio: 9.3, P=1.91E-084). Finally, we validated our findings in an analysis of an Italian PBC cohort. Our data suggested that the wGRS, utilizing genetic variants, was significantly associated with increased risk for PBC with consistent discriminant ability. Our study is a first step toward risk prediction for PBC
Reconsideration of Second Harmonic Generation from neat Air/Water Interface: Broken of Kleinman Symmetry from Dipolar Contribution
It has been generally accepted that there are significant quadrupolar and
bulk contributions to the second harmonic generation (SHG) reflected from the
neat air/water interface, as well as common liquid interfaces. Because there
has been no general methodology to determine the quadrupolar and bulk
contributions to the SHG signal from a liquid interface, this conclusion was
reached based on the following two experimental phenomena. Namely, the broken
of the macroscopic Kleinman symmetry, and the significant temperature
dependence of the SHG signal from the neat air/water interface. However,
because sum frequency generation vibrational spectroscopy (SFG-VS) measurement
of the neat air/water interface observed no apparent temperature dependence,
the temperature dependence in the SHG measurement has been reexamined and
proven to be an experimental artifact. Here we present a complete microscopic
analysis of the susceptibility tensors of the air/water interface, and show
that dipolar contribution alone can be used to address the issue of broken of
the macroscopic Kleinman symmetry at the neat air/water interface. Using this
analysis, the orientation of the water molecules at the interface can be
obtained, and it is consistent with the measurement from SFG-VS. Therefore, the
key rationales to conclude significantly quadrupolar and bulk contributions to
the SHG signal of the neat air/water interface can no longer be considered as
valid as before. This new understanding of the air/water interface can shed
light on our understanding of the nonlinear optical responses from other
molecular interfaces as well
- …