Incorporating a multiple discrete-continuous outcome in the generalized heterogeneous data model: Application to residential self-selection effects analysis in an activity time-use behavior model

This paper makes both a methodological contribution as well as an empirical contribution. From a methodological perspective, we propose a new econometric approach for the estimation of joint mixed models that include a multiple discrete choice outcome and a nominal discrete outcome, in addition to the count, binary/ordinal outcomes, and continuous outcomes considered in traditional structural equation models. These outcomes are modeled together by specifying latent underlying unobserved individual lifestyle, personality, and attitudinal factors that impact the many outcomes, and generate the jointness among the outcomes. From an empirical perspective, we analyze residential location choice, household vehicle ownership choice, as well as time-use choices, and investigate the extent of association versus causality in the effects of residential density on activity participation and mobility choices. The sample for the empirical application is drawn from a travel survey conducted in the Puget Sound Region in 2014. The results show that residential density effects on activity participation and motorized auto ownership are both associative as well as causal, emphasizing that accounting for residential self-selection effects are not simply esoteric econometric pursuits, but can have important implications for land-use policy measures that focus on neo-urbanist design

TWO NEW SPECIES OF POACEAE FROM INDIA

Two new species of Poaceae namely, Erayrostis santapaui K. G. Bhat & C. R. Nagendran and Chrysopogon pseitdozeylanicus K. G. Bhat & C. R. Nagendran have been described from materials collected by the senior author from Coorg- and South Kanara Districts of Karnataka State, India

ORIGINAL ARTICLE: Identification of Practical Pharmacology Skills Useful for Good Clinical Practice

Background: Awareness about animal ethics is increasing everywhere. This increased awareness coupled with strict regulations discouraging the use of animals for routine experiments have tied the hands of many pharmacologists. They are now forced to develop alternative experiments without using animals. At present, there is acute need to come out with more innovative and useful practical exercises for pharmacology practical sessions. In this background, the present study was undertaken to develop the much-needed alternative experiments. Aims and Objective: To identify new pharmacological practical skills useful for good clinical practice. Material and Methods: A pre-tested questionnaire was administered to 110 doctors of different categories like house surgeons, postgraduate students, assistant professors and professors who are working in a tertiary care hospital. They were asked to give their suggestions regarding new pharmacology practical skills useful for good clinical practice. Statistical analysis: Responses of the participants to the questions asked were tabulated and analyzed. Suggestions given by them were listed out and studied. Results: Use of emergency drugs, dosage calculation, drugs used in pregnancy, case discussions and prescription writing exercises received a lot of support from the participants. Research methodology, cost calculation, animal experiments and interpretation of data of animal experiments did not receive support from the participants. Suggestions given by the participants regarding useful pharmacological skills belonged to the areas like therapeutics, safe use of drugs, recent advances, analysis of information given by the medical representatives and analyzing articles in journals for knowing the efficacy of drugs. Conclusion: Exercises relevant to the clinical practice, as identified in this study, can be introduced as practical pharmacology exercises. Steps are to be taken to highlight the importance of research methodology and pharmaco-economics to the undergraduates

Evidence for long-term variability in the ultra high energy photon flux from Cygnus X-3

A time-correlation analysis of atmospheric Cerenkov pulses by a wide-angle photomultiplier system was previously shown to have present in it a nonrandom component which seemed associated with the Right Ascension (RA) range approx. 20+or-04h. A recent examination of multi-muon events recorded by a photon-decay detector shows a similar time-dependent effect, closely matching the previous results, supporting the suggestion that the effect is of cosmic origin. However, even though Cyg. X-3 lies well inside the region of peak intensity, it does not seem possible to ascribe to it the whole effect, for the implied photon flux appears too large to be reconciled to various gamma-ray measurements of Cyg. X-3. The original data were subjected to a phase-histogram analysis and it as found that only 2.5% of overall recorded data are compatible with a phase-dependent emission from Cyg. X-3. Assuming these events to be gamma rays yields a detected flux of (2.6 + or - 0.3) x 10 to the minus 12th power gamma cm -2s-1 above 5 x 10 to the 14th power eV. Comparing this value with more recent ultra high energy (UHE) photon data from the same source, it is suggested that the available data generally favor a long-term reduction in the Cyg. X-3 inferred luminosity ( 10 to the 13th power eV) by a factor of (1.8 + or - 0.3) per year