A PHENOMENOLOGICAL STUDY EXPLORING THE EDUCATIONAL PROBLEMS IN HIGHER EDUCATION OF VISUALLY IMPAIRMENT STUDENTS OF THE ONE CENTRAL UNIVERSITY OF INDIA

The concepts of phenomenological studies were focused worldly on the assessment of the lived experiences of disabled persons. The current studies were focusing on the lived experiences of visually impaired student in the one central University of India. These studies were conducted by personal interviews of ten visually impairment students. An outcome of this research explores many difficulties overcoming in the higher education learning process of the visually impaired student. This was due to the several major factors involved behinds this as deficient of modern devices of teaching, class lecture recorder, financial problems, over formalities burden by institutions at the time of examination and admission. Psychosocial adjustment in the new environments is another factor who affected education. Learning is a lifelong process which can affect individuals. Every moment of life of the visually impaired student from school to higher education has been a significant role in its own life and such an impact should not be denied. Therefore, this is necessary to provide special support for the improvement of career success among individuals who are visually impaired and avoid their educated barrier in the higher education system.  Article visualizations

Vitamin D levels and tumor necrosis factor-α activity in newly diagnosed patients with type 2 diabetes mellitus: An exploratory study in North-East India

Background: Diabetes poses a global threat, leading to hospitalizations and premature death if not managed properly. It involves tumor necrosis factor-α (TNF-α), an inflammatory cytokine, which binds to TNF-α receptor-1, triggering sphingomyelinase, and ceramide production. Vitamin D acts as an anti-inflammatory agent, reducing inflammatory cytokines and proinflammatory cell growth, and benefiting diabetes mellitus (DM). Aims and Objectives: The primary objective was to compare serum Vitamin D and TNF-α levels in diabetics and non-diabetics. The secondary objective was to explore Vitamin D and TNF-α correlation in newly diagnosed type 2 diabetes. Materials and Methods: A case–control study involved 92 subjects in each group. Data included demographics, clinical assessments, glycemic parameters, Vitamin D, and TNF-α. Statistical analysis used student’s t-test and Pearson correlation (P<0.05). Results: The cohort comprised 34 females (36.96%) and 58 males (63.04%). Cases had significantly higher glycemic levels: FBG (247.2±53.92 mg/dL vs. 91.45±16.64 mg/dL), postprandial plasma glucose (319.7±72.08 mg/dL vs. 111.3±21.76 mg/dL), and glycated hemoglobin (HbA1c) (10.39±2.41% vs. 5.43±0.48%). Mean serum Vitamin D in cases (22.63 ng/mL) was significantly lower than controls (58.15 ng/mL), and mean TNF-α in cases (5.01 pg/mL) was higher than controls (4.63 pg/mL, P<0.0001). HbA1c negatively correlated with serum Vitamin D (r=−0.7461) and positively with TNF-α (r=0.7831). Vitamin D correlated negatively with TNF-α (r=−0.6481). Conclusion: The study revealed lower serum Vitamin D and higher TNF-α levels in cases, with a significant inverse association. It also found an inverse link between Vitamin D and HbA1c and a strong positive correlation between HbA1c and TNF-α. Recognizing Vitamin D and TNF-α’s diagnostic significance promises innovative strategies for managing type 2 DM

Methylotroph bacteria and cellular metabolite carotenoid alleviate ultraviolet radiation-driven abiotic stress in plants

Increasing UV radiation in the atmosphere due to the depletion of ozone layer is emerging abiotic stress for agriculture. Although plants have evolved to adapt to UV radiation through different mechanisms, but the role of phyllosphere microorganisms in counteracting UV radiation is not well studied. The current experiment was undertaken to evaluate the role of phyllosphere Methylobacteria and its metabolite in the alleviation of abiotic stress rendered by ultraviolet (UV) radiation. A potential pink pigmenting methylotroph bacterium was isolated from the phylloplane of the rice plant (oryzae sativa). The 16S rRNA gene sequence of the bacterium was homologous to the Methylobacter sp. The isolate referred to as Methylobacter sp N39, produced beta-carotene at a rate (μg ml–1 d–1) of 0.45–3.09. Biosynthesis of beta-carotene was stimulated by brief exposure to UV for 10 min per 2 days. Carotenoid biosynthesis was predicted as y = 3.09 × incubation period + 22.151 (r2 = 0.90). The carotenoid extract of N39 protected E. coli from UV radiation by declining its death rate from 14.67% min–1 to 4.30% min–1 under UV radiation. Application of N39 cells and carotenoid extract also protected rhizobium (Bradyrhizobium japonicum) cells from UV radiation. Scanning electron microscopy indicated that the carotenoid extracts protected E. coli cells from UV radiation. Foliar application of either N39 cells or carotenoid extract enhanced the plant’s (Pigeon pea) resistance to UV irradiation. This study highlight that Methylobacter sp N39 and its carotenoid extract can be explored to manage UV radiation stress in agriculture

Isolation and Characterization of Phyllosphere Microflora of Maize

Maize is renowned as the "Queen of Cereals" and is one of the world's most significant cereal crops. Several foliar and stalk rot diseases affect maize crops. The illness affected the majority of the cultivars that were issued. The influence of overuse of chemical fungicides on the environment and food safety has become a serious problem with the rise of ecological agriculture. Epiphytes are phyllosphere residents who can include a wide range of bacteria and filamentous fungi. Microbial interactions in the phyllosphere repress and promote plant pathogen colonisation and infection of tissues, increasing disease resistance and agricultural crop productivity, implying that phyllosphere microorganisms can play a key role in growth promotion and disease suppression. Bacteria from individual colonies were studied. Individual colony bacteria was examined for shape, size, colour, Gram staining, endospore staining, elevation and texture for morphological studies. Different biochemical tests viz., Catalase, Oxidase, Voges Prausker’s, Indole, Methyl red, Gelatin liquefaction were done for phyllosphere bacteria

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Not AvailableCastor (Ricinus communis L.) and groundnut (Arachis hypogaea L.) are the two important oilseed crops grown in India. Of the various soil borne diseases, the wilt caused by Fusarium oxysporum f. sp. ricini in castor and the collar rot caused by Aspergillus niger in groundnut are the major diseases. In the present study, effect of individual and combined application of seed coat polymers (synthetic polymer & chitosan), fungicides viz., carbendazim, vitavax+thiram (which were taken from poisoned food technique results) and two Trichoderma species viz., Trichoderma asperellum TaDOR 7316 and Trichoderma harzianum Th4d were used for seed coating and determined the effective combination to promote plant growth and control those soil borne diseases of castor and groundnut under in vitro conditions. In case of castor the treatment T13 (Chitosan + Carbendazim + T. harzianum Th4d) significantly increased the seedling growth and vigour in both uninoculated and pathogen inoculated condition than controls. In groundnut the treatment T12 (Chitosan + T. asperellum TaDOR 7316) exquisite in the seedling growth under uninoculated condition whereas under pathogen inoculation the treatment T13 (Chitosan + vitavax +thiram + T. asperellum TaDOR 7316) was the most effective.Not Availabl

Effect of Elevated CO2 and Temperature on Chlorophyll Content and Growth Attributes of Rice-wheat Cropping System in Central India

Rice-wheat is a major cropping system in India and it is predicted that the productivity of both crops will decline due to climate change factors including elevated CO2 and temperature. To define the mechanisms, a field experiment was carried out to evaluate the effect of elevated CO2 and temperature on growth attributes of rice and wheat crops using a Free Air CO2 Enrichment (FACE) system. The treatments were ambient CO2+ambient temperature, elevatedCO2of 600ppm+ambient temperature, ambient CO2 + elevated temperature (+2°C), ambient CO2+elevated temperature (+3°C), elevated CO2 600 ppm +elevated temperature (+2°C) and elevated CO2 600ppm +elevated temperature (+3°C). Elevated CO2 and elevated temperature (+2°C or +3°C) strongly affected the crop growth. Elevated CO2 stimulated leaf chlorophyll content, root-shoot length and biomass yield. However, elevated temperature inhibited chlorophyll content in both the crops. Elevated CO2enhanced chlorophyll content by 12.9–19% in rice and 8.8–16.5%in wheat. Elevated temperature reduced chlorophyll content by a range of 20.5-27.3% in rice and 6.3-11.5% in wheat. Combined effect of elevated CO2and elevated temperature decreased the leaf total chlorophyll and plant biomass in both crops. Study highlights that elevated CO2 concentration and rising temperature may affect the photosynthesis and productivity of rice and wheat crop in central India

Detection of embryonic stem cell markers in adult human adipose tissue-derived stem cells

Background: Bone marrow transplantation is already an established therapy, which is now widely used in medicine to treat leukemia, lymphoma, and several inherited blood disorders. The culture of multilineage cells from easily available adipose tissue is another source of multipotent mesenchymal stem cells, and is referred to as adipose tissue-derived stem cells (ADSCs). While ADSCs are being used to treat various conditions, some lacuna exists regarding the specific proteins in these. It was therefore decided to analyze the specific proteins of embryonic cells in ADSCs. Aims: To analyze the specific protein of embryonic stem cells (ESCs) in ADSCs. Materials and Methods: Adult human adipose tissue-derived stem cells (ADSCs) were harvested from 13 patients after obtaining patients′ consent. The specific markers of ESCs included surface proteins CD10, CD13, CD44, CD59, CD105, and CD166, and further nucleostemin,(NS) NANOG, peroxisome proliferator-activated receptor-gγ, collagen type 1 (Coll1), alkaline phosphate, (ALP) osteocalcin (OC), and core binding factor 1 (Cbfa1) were analyzed using by reverse transcription-polymerase chain reaction, (RT-PCR) immunofluorescence (IF), and western blot. Results: All the proteins were expressed distinctly, except CD13 and OC. CD13 was found individually with different expressions, and OC expression was discernable. Conclusions: Although the ESC with its proven self-renewal capacity and pluripotency seems appropriate for clinical use, the recent work on ADSCs suggests that these adult stem cells would be a valuable source for future biotechnology, especially since there is a relative ease of procurement