Third workshop on exploratory search and interactive data analytics (ESIDA)

This is the third edition of the Workshop on Exploratory Search and Interactive Data Analytics (ESIDA). This series of workshops emerged as a response to the growing interest in developing new methods and systems that allow users to interactively explore large volumes of data, such as documents, multimedia or specialised collections, such as biomedical datasets. There are various approaches to supporting users in this interactive environment ranging from the development of new algorithms through visualisation methods to analysing users' search patterns. The overarching goal of ESIDA is to bring together researchers working in areas that span across multiple facets of exploratory search and data analytics to discuss and outline research challenges for this novel area. © 2019 ACM.Peer reviewe

Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes

ObjectiveThis study aimed to explore the long term outcomes of patients with intermittent claudication (IC) who completed supervised exercise therapy (SET) vs. those who declined or prematurely discontinued SET, focusing on the incidence of chronic limb threatening ischaemia (CLTI), revascularisation, major adverse limb events (MALE), and major adverse cardiovascular events (MACE).MethodsRetrospective registry analysis of consecutive patients with IC who were referred for SET between March 2015 and August 2016 and followed up for a minimum of five years. Serial univariable analysis and logistic regression were performed to identify the statistically significant clinical variables that were independent predictors of each outcome measure. The resulting statistically significant variables were used to guide 1:1 propensity score matching (PSM) using the nearest neighbour method with a calliper of 0.2. Cox proportional hazards regression was used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for the association between SET and the outcomes of interest.ResultsTwo hundred and sixty-six patients were referred to SET between March 2015 and August 2016. Of these, 64 patients completed SET and 202 patients did not. After PSM, 49 patients were analysed in each cohort. The Cox proportional hazards analysis revealed a significant association between completion of SET and revascularisation requirement (HR 0.46 95% CI 0.25 – 0.84; p = .011), completion of SET and progression to CLTI (HR 0.091, 95% CI 0.04 – 0.24; p < .001), completion of SET and MACE (HR 0.52; 95% CI 0.28 – 0.99; p = .05) and completion of SET and MALE (HR 0.28, 95% CI 0.13 – 0.65; p = .003). The Harrell’s C index for all of these models were greater than 0.75, indicating good predictive accuracy.ConclusionCompletion of SET is associated with better outcomes in patients who completed SET compared to patients who declined or discontinued SET with respect to clinically important cardiovascular outcomes over seven years