Syntheses, spectral, thermal and pH-metric studies on bivalent metal ion complexes of N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine

A novel carboxyamide ligand has been synthesized using maleic anhydride and ethylenediamine. Co(II), Ni(II), Cu(II) and Pd(II) complexes of the ligand, i.e., N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine [H2L] have been prepared and characterized by elemental analyses,  IR, electronic, 1H NMR, EPR spectral and thermal studies. It is revealed by IR and 1H NMR spectral studies that the ligand coordinated to the metal ions through deprotonated carboxylate oxygen and non-deprotonated amide nitrogen in all the complexes. It is suggested by electronic spectral and magnetic moment studies that N2O2 coordination is around each metal center with a strong field square planar chromophore. All the complexes have been studied by TGA and DTA studies done simultaneously. The complex formation between ligand and metal ions [Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)] has also been studied pH metrically in 75% aqueous DMF solution at 298 K in 0.1 M NaClO4. The probable structures of the complexes have also been proposed

Spectral and thermal characterization of new biomimetic polydentate amide ligands

1106-1108Complexes of manganese(II) and nickel(II) with N,N'- bis(3- carboxy-1 -oxopropanyl)- 1, 2-ethylenediamine (C10H16N2O6,L1) N,N'- bis(3-carboxy-1 -oxopropanyl)- 1,  2-phenylediamine (C14H16 N2O6,L2),  N,N'- bis(3-carboxy-1 -oxophenelenyl)- 1 , 2- phenylenediamine (C22H16, N2O6,L3)and N,N'- bis(3-carboxy-1- oxoprop- 2-enyl)-1, 2-phenylenediamine (C14H12N2O6, L4) have been prepared and characterized by elemental analysis, vibrational spectra, magnetic susceptibility measurements, electronic spectra and thermal studies. Vibrational spectra indicates coordination of amide and carboxylate oxygens of the ligands giving a MO4 chromophore. Electronic spectra support square planar geometry around nickel(II) and tetrahedral around manganese(II). NiL1 complex has the maximum activation energy and NiL2 complex has the minimum activation energy

Synthesis and spectral studies of zinc(II) and palladium(II) complexes of amide ligands derived from 2-aminopyridine

598-600A few complexes of Zn(II) and Pd(II) with N-(2-pyridyl)- 3-carboxypropanamide and N-(2-pyridyl)-2-carboxybenzamide derived from 2-aminopyridine have been prepared and characterised on the basis of elemental analysis, conductivity measurements, thermal and spectral (IR, 1H NMR, UV /vis) studies. Molar conductivities indicate non-electrolytic behaviour of most of the complexes. Spectral studies show the coordination of Zn(ll) through amide oxygen and pyridine nitrogen atom, while in case of Pd(II), pyridine nitrogen atom alone coordinates. On the basis of these studies, probable structures of the complexes have been assigned

Solid phase extraction of lead using modified cellulose in natural, wastewater and egg samples

413-4182-Pyridyliminosalicylcellulose has been used for the sorption and estimation of lead(II) by column and batch techniques. The distribution coefficient (D) was found to be 4.3102 for the lead ion. The detection limit was found to be 3.82 ng mL-1 and the breakthrough volume was 20 mL. The present matrix coupled with FAAS has been used to enrich and determine the lead ions in natural and wastewater (RSD ~ 2.52-3.50%) and egg samples (RSD ~ 2.73%). The method is simple, rapid and relatively free from interference and satisfactorily applied for the estimation of lead (~98% recovery) in natural, wastewater and egg samples

Spectral and thermal studies of homodinuclear and heterodinuclear glutathione complexes

1205-1207The complexes of the types [M2LSO4.2H2O] where L=GSH, M = Co(II), Cu(II), Zn(II), Cd(II) and [MM'LSO4.2H2O] where L = GSH, M = Cu(II), M' = Zn(II) and M = Co(II), M' = Cd(II)] have been prepared and characterized by elemental analysis, magnetic susceptibility measurements, JR, EPR, electronic spectral studies and thermal analysis. Deprotonation and coordination of thiol group occurs and glycine residue binds with the metal ions in all the complexes. Copper(II) and cobalt(II) complexes show low magnetic moment. EPR spectral data show that complexes have planar geometry. Ligand to metal charge transfer are observed in all the complexes and d-d transition are also observed in copper(II) and cobalt(II) complexes. Thermal decomposition of all the complexes proceeds via first order kinetics

Syntheses, spectral, thermal and pH-metric studies on bivalent metal ion complexes of N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine

1065-1071A novel carboxyamide ligand has been synthesized using maleic anhydride and ethylenediamine. Co(II), Ni(II), Cu(II) and Pd(II) complexes of the ligand, i.e., N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine [H2L] have been prepared and characterized by elemental analyses, IR, electronic, 1H NMR, EPR spectral and thermal studies. It is revealed by IR and 1H NMR spectral studies that the ligand coordinated to the metal ions through deprotonated carboxylate oxygen and non-deprotonated amide nitrogen in all the complexes. It is suggested by electronic spectral and magnetic moment studies that N2O2 coordination is around each metal center with a strong field square planar chromophore. All the complexes have been studied by TGA and DTA studies done simultaneously. The complex formation between ligand and metal ions [Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)] has also been studied pH metrically in 75% aqueous DMF solution at 298 K in 0.1 M NaClO4. The probable structures of the complexes have also been proposed

Role Of Plant-Based Bioflavonoids in Combating Tuberculosis

Innovative strategies are required to address the ongoing threat of tuberculosis (TB), which continues to be a serious worldwide health issue. Growing interest has been paid to plant-based bioflavonoids because of their potential as TB adjunctive treatments. This chapter offers a thorough examination of the varied function of bioflavonoids in TB treatment. The first sections highlight bioflavonoids' natural defense roles in plants while describing their chemical diversity and origins. We study the mechanisms of action of bioflavonoids on Mycobacterium TB, including how they interfere with biofilm development, virulence factors, and host immunological responses. Notably, the potential for decreased drug resistance and shortened treatment durations is highlighted when discussing the synergistic effects between bioflavonoids and traditional TB medications. The anti-inflammatory properties of bioflavonoids are examined in the context of TB pathogenesis, addressing their role in modulating inflammatory responses and mitigating tissue damage. Clinical studies evaluating bioflavonoid efficacy, safety, and bioavailability are reviewed, providing insights into their therapeutic potential. Challenges associated with bioavailability and formulation are also discussed, highlighting strategies to optimize drug delivery.Incorporating ethnobotanical perspectives, we explore historical plant-based remedies for TB and the integration of traditional knowledge with modern research. The abstract concludes by outlining future directions, emphasizing promising bioflavonoid candidates for TB treatment, targeting latent infections, and advocating for collaborative, interdisciplinary research efforts. Ultimately, this chapter underscores the promising role of plant-based bioflavonoids as a potential avenue for enhancing the efficacy and resilience of TB treatment strategies, offering hope for improved outcomes in TB management