Safety and Efficacy of Oxcarbazepine: Results of Randomized, Double‐Blind Trials

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90287/1/phco.20.12.152S.35254.pd

Lone Wolf Terrorism: Types, Stripes, and Double Standards

The recent spike in mass shootings, topped by the October 1, 2017, Las Vegas massacre, dubbed the “deadliest mass shooting in modern U.S. history,” has brought newfound urgency and attention to lone wolf violence and terrorism. Although a topic of pressing concern, the phenomenon—which centers on mass violence inflicted by one individual—is underexamined and undertheorized within legal literature. This scholarly neglect facilitates flat understandings of the phenomenon and enables the racial and religious double standards arising from law enforcement investigations and prosecutions of white and Muslim lone wolves. This Essay contributes a timely reconceptualization of the phenomenon, coupled with a typology adopted from social science, for understanding the myriad forms of lone wolf terrorism. In addition to contributing the theoretical frameworks to further examine lone wolf terrorism within legal scholarship, this Essay examines how the assignment of the lone wolf designation by law enforcement functions as: (1) a presumptive exemption from terrorism for white culprits and (2) a presumptive connection to terrorism for Muslim culprits. This asymmetry is rooted in the distinct racialization of white and Muslim identity, and it is driven by War on Terror baselines that profile Muslim identity as presumptive of a terror threat

Righting the Rift Between Muslim and American: Celebrating Abdullahi An-An\u27im

This Essay is a special contribution to the Journal of Law and Religion and the Emory International Law Review, honoring the work of Professor Abdullahi An-Na’im and his impact on my work, and more broadly, discourses on Islam in America, rights, and citizenship. This Essay, celebrating the landmark work of Professor An-Na’im and its impact on my scholarly and public work, will examine these two fronts. By challenging the political constructions of Americanness and Muslim identity that prevailed on the right, left, and in-between, An-Na’im inspired new frontiers of thought and thinkers that followed his footsteps. This line of intellectual impact emanates from his landmark contributions on human rights and Islamic law, but also stands alone to inform the work of thinkers, like myself, who write beyond the bounds of the spheres where Professor An-Na’im made his name

Monotherapy Trials with Gabapentin for Partial Epilepsy

The efficacy and safety of gabapentin as monotherapy for treatment of partial onset seizures were evaluated in three large multicenter, double-blind, parallel-group, dose-controlled trials. In the first trial, 275 outpatients with refractory partial epilepsy maintained on stable doses of one or two antiepileptic drugs (AEDs) were switched to gabapentin (GBP) monotherapy at 600 mg, 1200 mg, or 2400 mg daily. Patients were required to exit the 26-week double-blind phase of the study if they experienced worsening of seizure frequency. With respect to time to exit, there was no statistically significant difference among the three groups; only 3% of patients withdrew from the trial because of adverse events. In the second study, 82 hospitalized patients with medically refractory epilepsy were tapered off baseline AEDs and randomly assigned to GBP monotherapy at 300 mg/day or 3600 mg/day. Patients remained in the trial for a maximum of 8 days but had to exit the trial if they experienced one or more exit events. Time to exit was significantly longer in patients in the 3600-mg group (151 h) compared with those in the 300-mg group (85 h) ( p = 0.0001). None of the patients withdrew from the trial because of side effects. In the third study, 292 patients with newly diagnosed partial seizures were randomized to GBP 300, 900, or 1800 mg/day or to carbamazepine (CBZ) 600 mg/day. Patients remained in the trial for up to 6 months or until they experienced an exit event. Mean time to exit was significantly longer for patients who received GBP 900 mg/day ( p = 0.02) or 1800 mg/day ( p = 0.04) compared with those who received 300 mg/day. The completion rate for the CBZ group (37%) was similar to that of the GBP 900-mg (39%) and 1800-mg (38%) groups. Patients receiving CBZ had a higher withdrawal rate because of adverse events compared with the GBP 900-mg and 1800-mg groups. The results of these trials provide good evidence of the efficacy and safety of GBP as monotherapy for the treatment of partial-onset seizures.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65608/1/j.1528-1157.1999.tb00927.x.pd

A Demographic Threat? Proposed Reclassification of Arab Americans on the 2020 Census

“Arab Americans are white?” This question—commonly posed as a demonstration of shock or surprise—highlights the dissonance between how “Arab” and “white” are discursively imagined and understood in the United States today. These four words also encapsulate the dilemma that currently riddles Arab Americans. The population finds itself interlocked between formal classification as white, and de facto recognition as nonwhite. The Office of Management and Budget (OMB), the government agency that oversees the definition, categorization, and construction of racial categories, currently counts people from the Middle East and North Africa (MENA) as white. The United States Census Bureau (Census Bureau), the agency responsible for collecting and compiling demographic data about the American people, adopts these definitions and classifications for the administration of its decennial census. Since the racially restrictive “Naturalization Era,” Arab Americans have been legally classified as white