Efecto del extracto hidroalcohólico de las flores de overo cordia lutea en la toxicidad hepática inducida por paracetamol en ratas holtzman macho

El estudio tiene el objetivo de Identificar componentes químicos en el extracto hidroalcohólico de las flores de overo Cordia lutea, y Determinar el efecto del extracto hidroalcohólico de las flores de overo Cordia lutea en la reducción de las alteraciones de los parámetros físicos y bioquímicos producidas en la toxicidad hepática inducida por paracetamol en ratas Holtzman macho. La metodología del estudio responde a un diseño experimental, y el Tipo y nivel: Analítico, experimental, observacional, exploratorio y descriptivo, en una muestra de 24 ratas Holtzman macho. Los métodos y técnicas empleados fueron: Método de maceración hidroalcohólica, marcha fitoquimicaThe objective of the study is to identify chemical components in the hydroalcoholic extract of Cordia lutea overo flowers, and to determine the effect of the hydroalcoholic extract of cordia lutea overo flowers in the reduction of the alterations of the physical and biochemical parameters produced in the Hepatic toxicity induced by paracetamol in male Holtzman rats. The methodology of the study responds to an experimental design, and the Type and level: Analytical, experimental, observational, exploratory and descriptive, in a sample of 24 male Holtzman rats. Methods of hydroalcoholic maceration, phytochemical marc

Crear soluciones empresariales

El objetivo del presente trabajo es crear una empresa de consultoría organizacional llamada CREAR SOLUCIONES EMPRESARIALES SA, cuya actividad económica se enfocará en la comercialización de servicios de consultoría organizacional desarrollando procesos de reclutamiento y selección de personal a través de la utilización del software Digilog UK. Para la creación de dicha empresa se utilizó la metodología del PMI para definir y construir dicho plan de negocios

Household factors and under-five mortality in Bankass, Mali: results from a cross-sectional survey.

BackgroundRural parts of Mali carry a disproportionate burden of the country's high under-five mortality rate. A range of household factors are associated with poor under-five health in resource-limited settings. However, it is unknown which most influence the under-five mortality rate in rural Mali. We aimed to describe household factors associated with under-five mortality in Bankass, a remote region in central Mali.MethodsWe analysed baseline household survey data from a trial being conducted in Bankass. The survey was administered to households between December 2016 and January 2017. Under-five deaths in the five years prior to baseline were documented along with detailed information on household factors and women's birth histories. Factors associated with under-five mortality were analysed using Cox regression.ResultsOur study population comprised of 17,408 under-five children from 8322 households. In the five years prior to baseline, the under-five mortality rate was 152.6 per 1000 live births (158.8 and 146.0 per 1000 live births for males and females, respectively). Living a greater distance from a primary health center was associated with a higher probability of under-five mortality for both males (adjusted hazard ratio [aHR] 1.53 for ≥10 km versus < 2 km, 95% confidence interval [CI] 1.25-1.88) and females (aHR 1.59 for ≥10 km versus < 2 km, 95% CI 1.27-1.99). Under-five male mortality was additionally associated with lower household wealth quintile (aHR 1.47 for poorest versus wealthiest, 95%CI 1.21-1.78), lower reading ability among women of reproductive age in the household (aHR 1.73 for cannot read versus can read, 95%CI 1.04-2.86), and living in a household with access to electricity (aHR 1.16 for access versus no access, 95%CI 1.00-1.34).ConclusionsU5 mortality is very high in Bankass and is associated with living a greater distance from healthcare and several other household factors that may be amenable to intervention or facilitate program targeting

Community case management to accelerate access to healthcare in Mali: A realist process evaluation nested within a cluster randomised trial

The Proactive Community Case Management (ProCCM) trial in Mali reinforced the health system across both arms with user fee removal, professional Community Health Workers (CHWs), and upgraded primary health centres (PHCs)-and randomized village-clusters to receive proactive home visits by CHWs (intervention) or fixed site-based services by passive CHWs (control). Across both arms, sick children's 24-hour treatment and pregnant women's four or more antenatal visits doubled, and under-five mortality halved, over three years compared to baseline. In the intervention arm, proactive CHW home visits had modest effects on children's curative and women's antenatal care utilization, but no effect on under-five mortality, compared to the control arm. We aimed to explain these results by examining implementation, mechanisms, and context in both arms. We conducted a process evaluation with a mixed method convergent design that included 79 in-depth interviews with providers and participants over two time-points, surveys with 195 providers, and secondary analyses of clinical data. We embedded realist approaches in novel ways to test, refine, and consolidate theories about how ProCCM worked, generating three context-intervention-actor-mechanism-outcome nodes that unfolded in a cascade. First, removing user fees and deploying professional CHWs in every cluster enabled participants to seek health sector care promptly and created a context of facilitated access. Second, health systems support to all CHWs and PHCs enabled equitable, respectful, quality healthcare, which motivated increased, rapid utilization. Third, proactive CHW home visits facilitated CHWs and participants to deliver and seek care, and build relationships, trust, and expectations, but these mechanisms were also activated in both arms. Addressing multiple structural barriers to care, user fee removal, professional CHWs, and upgraded clinics interacted with providers' and patients' agency to achieve rapid care and child survival in both arms. Proactive home visits expedited or compounded mechanisms that were activated and changed the context across arms

Souleymaan

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian

L'an 2000

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian

Dalulu

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian

Baayi Aboo

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian

Saltige

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian

Doole

Senegalese band featuring solo and chorus singers accampanied by kora, xalam, sabar, guitar and pian