Etudes in situ de la formation du carbonate de calcium CaCO3 synthétisé en milieu aqueux sous pression de CO2

National audienc

Synthesis and characterization of CaCO3 C biopolymers hybrid nanoporous microparticles for cancer damaged bone therapy

International audienc

Microencapsulation of Proteins within Polymeric and Inorganic Particles using Supercritical CO2 Media

International audienc

Encapsulation de proteins thérapeutiques dans des microspheres de CaCO3 élaborées en milieu CO2 supercritique

National audienc

Microencapsulation of proteins within CaCO3 microspheres using supercritical CO2 media

International audienc

Synthesis of hollow vaterite CaCO(3) microspheres in supercritical carbon dioxide medium

We here describe a rapid method for synthesizing hollow core, porous crystalline calcium carbonate microspheres composed of vaterite using supercritical carbon dioxide in aqueous media, without surfactants. We show that the reaction in alkaline media rapidly conducts to the formation of microspheres with an average diameter of 5 mu m. SEM, TEM and AFM observations reveal that the microspheres have a hollow core of around 0.7 mu m width and are composed of nanograins with an average diameter of 40 nm. These nanograins are responsible for the high specific surface area of 16 m(2) g(-1) deduced from nitrogen absorption/desorption isotherms, which moreover confers an important porosity to the microspheres. We believe this work may pave the way for the elaboration of a biomaterial with a large potential for therapeutic as well as diagnostic applications

Encapsulation of growth factors into calcium carbonate microparticles elaborated in supercritical CO2 medium

National audienc

Development of a supercritical precipitation process of calcium carbonate for biomedical applications

International audienc

Elaboration of composite calcium carbonate microparticles in supercritical CO2

International audienc

Supercritical CO2 as highly efficient innovative process for proteins encapsulation

International audienc