Effect of Aqueous Extract of Passiflora edulis on Biochemical and Hematological Parameters of Wistar Albino Rats

Passiflora edulis is traditionally used in folk lore medicine for the treatment of various ailments. To validate its use in traditional medicine, it is important to evaluate its toxicity in the animal system. Therefore, this study aimed to evaluate the toxicological effects of oral administration of aqueous leaf extract of P. edulis in Wistar albino rats. Acute toxicity tests were conducted by the oral administration of 200, 500, 1000 and 2000 mg/kg body weight of the animal. In subacute study, they were administered with various doses of aqueous extract of P. edulis (100, 200, 300, and 400 mg/kg body weight) to evaluate its toxicity for a period of 7 days. The effect of aqueous extract of P. edulis on organ weight, hematological, renal, and hepatic markers were analyzed. In acute toxicity study, no mortality was seen with in 24 h of the administration of P. edulis extract. No signs of neurological and behavioral changes were noticed with in 72 h. In the subacute study, the extract intake has not changed the hematological parameters such as RBC, WBC, and platelets and it was also found that the plasma level of amino transferases, ALP, urea, uric acid and, creatinine were also not altered by the administration of P. edulis extract throughout the study. The weight of organ was found to be unaltered in all the doses selected. The acute toxicity study reveals that the oral administration of the extract was found to be safe up to the dose level of 2000 mg/kg. The subacute study indicates that the extract is safe on the bone marrow function and it is neither hepatotoxic nor nephrotoxic. This supports the safety use of the aqueous extract of P. edulis in pharmacological studies

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Not AvailableAn experiment was conducted at Indian Institute of Rice Research, Hyderabad, toassess the response of 34 hybrid rice parental lines to 120mM Nacl salt stress at germination stage. All the genotypes significantly responded to salt stress and most of the genotypes showed tolerance to threshold salt level and the results clearly depicted that germination stage is moderately tolerant to salinity. Root and shoot length of all cultivars were significantly affected by salt stress, The genotypes BK49-76, BK36-167, INDAM300-007, AjayaR, FL-478 and DRRH-2 manifested maximum tolerance where as genotypes BCW 56, IR 58025B, APMS6B showed susceptibility on par with IR28 at germination stage. The most of the genotypes were tolerant to salinity at seed germination which is an indicator for raising nursery in salt affected soils.Not Availabl

Not Available

Not AvailableAn experiment was conducted at Indian Institute of Rice Research, Hyderabad, to assess the response of 34 hybrid rice parental lines to 120mM Nacl salt stress at germination stage. All the genotypes significantly responded to salt stress and most of the genotypes showed tolerance to threshold salt level and the results clearly depicted that germination stage is moderately tolerant to salinity. Root and shoot length of all cultivars were significantly affected by salt stress, The genotypes BK49-76, BK36-167, INDAM300-007, AjayaR, FL-478 and DRRH-2 manifested maximum tolerance where as genotypes BCW 56, IR 58025B, APMS6B showed susceptibility on par with IR28 at germination stage. The most of the genotypes were tolerant to salinity at seed germination which is an indicator for raising nursery in salt affected soils.Not Availabl

Bicontinuous Nanospheres from Simple Amorphous Amphiphilic Diblock Copolymers

Bicontinuous nanospheres have been observed (although rarely) from a variety of block copolymers with architectural and compositional complexity, and often in the presence of additives. Unlocking key features involved in their formation presents possibilities for bicontinuous aggregates with varied functionality and application. An attractive prospect is the ability to form them from much simpler polymeric structures derived from facile syntheses. To that end, we herein report the formation of bicontinuous aggregates from simple amorphous amphiphilic diblock copolymers of poly(ethylene oxide)-b-poly(n-butyl methacrylate), analogous to our previous report of the same from a semicrystalline comb-like block copolymer. Moreover, we demonstrate that polymorphism can be achieved by altering the relative block proportions and the nonselective cosolvent. We find that the polymeric structure is not the dominating factor in the formation of bicontinuous nanospheres but that the choice of cosolvent for the hydrophilic block appears to have greater influence on determining the end morpholog