Participant Reactions to Survey Research in the General Population After Terrorist Attacks

There remains concern that survey research after a disaster can precipitate or exacerbate distress among study participants. The authors surveyed 5,774 persons in three random-digit-dial telephone surveys of the general population of New York City conducted 1–2 months, 4–5 months, and 6–9 months after the terrorist attack on September 11, 2001. Overall, 746 (12.9%) people who finished the surveys said that the survey questions were upsetting but only 57 (1.0% overall) were still upset at the end of the interview, and 19 (0.3%) wanted assistance from a counselor. Ten persons who did not finish the survey also received counselor assistance. Persons with mental health symptoms were more likely to find the survey questions emotionally upsetting as were participants who lacked salutary resources, including health insurance and a regular health care provider. Although relatively few of those interviewed found the survey assessment disturbing, the presence of a small number of respondents who wanted mental health assistance suggests the need for a mental health backup system for research conducted soon after exposure to large-scale traumatic events.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/40338/2/Galea_Participant Reactions to Survey Research_2005.pd

Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus

Objectives : Circulating low molecular weight (<10 kDa) fluorophores (LMW-F) measured by non-specific fluorescence spectroscopy may detect small advanced glycation end-products (AGEs) not recognized by other assays. This longitudinal study assessed correlates of LMW-F and predictive power of LMW-F levels for vascular health in Type 1 diabetes (T1DM) patients. Methods : Fasting patients with T1DM (n=37) were studied twice at intervals of 12-60 months (mean±SD, 33±15 months). LMW-F levels were also measured once in 112 healthy control subjects. Results : Relative to controls, LMW-F levels were higher in diabetic subjects at initial and final time points (mean±SD), 5.4±1.9 AU/ml and 4.5±1.8 AU/ml respectively vs. 3.8±2.1 AU/ml p=0.0001 and p=0.06). Baseline LMW-F levels predicted subsequent hs-CRP and oxLDL/LDL values. LMW-F levels decreased significantly over time in diabetes (5.4±1.9 vs. 4.5±1.8 AU/ml p=0.02). Rises in LMW-F levels in individual diabetic subjects correlated significantly with worsening renal function (BUN), glycemia (HbA1c) and with vascular dysfunction (systemic vascular resistance). Conclusions : LMW-F levels predict levels of inflammation and oxidation in T1DM. Changes in LMW-F levels in T1DM reflect variations in glycemia and renal function. Biochemical characterization of LMW-F would facilitate understanding of the potential utility of LMW-F as a therapeutic target

Cross-Language Perception of Cantonese Vowels Spoken by Native and Non-native Speakers

This study examined the effect of native language background on listeners’ perception of native and non-native vowels spoken by native (Hong Kong Cantonese) and non-native (Mandarin and Australian English) speakers. They completed discrimination and an identification task with and without visual cues in clear and noisy conditions. Results indicated that visual cues did not facilitate perception, and performance was better in clear than in noisy conditions. More importantly, the Cantonese talker’s vowels were the easiest to discriminate, and the Mandarin talker’s vowels were as intelligible as the native talkers’ speech. These results supported the interlanguage speech native intelligibility benefit patterns proposed by Hayes-Harb et al. (J Phonetics 36:664–679, 2008). The Mandarin and English listeners’ identification patterns were similar to those of the Cantonese listeners, suggesting that they might have assimilated Cantonese vowels to their closest native vowels. In addition, listeners’ perceptual patterns were consistent with the principles of Best’s Perceptual Assimilation Model (Best in Speech perception and linguistic experience: issues in cross-language research. York Press, Timonium, 1995)