1,351 research outputs found
A teleparallel model for the neutrino
The main result of the paper is a new representation for the Weyl Lagrangian
(massless Dirac Lagrangian). As the dynamical variable we use the coframe, i.e.
an orthonormal tetrad of covector fields. We write down a simple Lagrangian -
wedge product of axial torsion with a lightlike element of the coframe - and
show that variation of the resulting action with respect to the coframe
produces the Weyl equation. The advantage of our approach is that it does not
require the use of spinors, Pauli matrices or covariant differentiation. The
only geometric concepts we use are those of a metric, differential form, wedge
product and exterior derivative. Our result assigns a variational meaning to
the tetrad representation of the Weyl equation suggested by J.B.Griffiths and
R.A.Newing.Comment: 4 pages, REVTe
Direct path from microscopic mechanics to Debye shielding, Landau damping, and wave-particle interaction
The derivation of Debye shielding and Landau damping from the -body
description of plasmas is performed directly by using Newton's second law for
the -body system. This is done in a few steps with elementary calculations
using standard tools of calculus, and no probabilistic setting. Unexpectedly,
Debye shielding is encountered together with Landau damping. This approach is
shown to be justified in the one-dimensional case when the number of particles
in a Debye sphere becomes large. The theory is extended to accommodate a
correct description of trapping and chaos due to Langmuir waves. Shielding and
collisional transport are found to be two related aspects of the repulsive
deflections of electrons, in such a way that each particle is shielded by all
other ones while keeping in uninterrupted motion.Comment: arXiv admin note: substantial text overlap with arXiv:1310.3096,
arXiv:1210.154
A Computational Investigation of Cardiac Caveolae as a Source of Persistent Sodium Current
Recent studies of cholesterol-rich membrane microdomains, called caveolae, reveal that caveolae are reservoirs of “recruitable” sodium ion channels. Caveolar channels constitute a substantial and previously unrecognized source of sodium current in cardiac cells. In this paper we model for the first time caveolar sodium currents and their contributions to cardiac action potential morphology. We show that the β-agonist-induced opening of caveolae may have substantial impacts on peak overshoot, maximum upstroke velocity, and ultimately conduction velocity. Additionally, we show that prolonged action potentials and the formation of potentially arrhythmogenic afterdepolarizations, can arise if caveolae open intermittently throughout the action potential. Our simulations suggest that caveolar sodium current may constitute a route, which is independent of channelopathies, to delayed repolarization and the arrhythmias associated with such delays
A Barren Landscape?
We consider the generation of a non-perturbative superpotential in F-theory
compactifications with flux. We derive a necessary condition for the generation
of such a superpotential in F-theory. For models with a single volume modulus,
we show that the volume modulus is never stabilized by either abelian
instantons or gaugino condensation. We then comment on how our analysis extends
to a larger class of compactifications. From our results, it appears that among
large volume string compactifications, metastable de Sitter vacua (should any
exist) are non-generic.Comment: 14 pages, comments adde
A symplectic, symmetric algorithm for spatial evolution of particles in a time-dependent field
A symplectic, symmetric, second-order scheme is constructed for particle
evolution in a time-dependent field with a fixed spatial step. The scheme is
implemented in one space dimension and tested, showing excellent adequacy to
experiment analysis.Comment: version 2; 16 p
On the Bartnik extension problem for the static vacuum Einstein equations
We develop a framework for understanding the existence of asymptotically flat
solutions to the static vacuum Einstein equations with prescribed boundary data
consisting of the induced metric and mean curvature on a 2-sphere. A partial
existence result is obtained, giving a partial resolution of a conjecture of
Bartnik on such static vacuum extensions. The existence and uniqueness of such
extensions is closely related to Bartnik's definition of quasi-local mass.Comment: 33 pages, 1 figure. Minor revision of v2. Final version, to appear in
Class. Quantum Gravit
Platelet-activating factor acetylhydrolase and haemophagocytosis in the sepsis syndrome.
Sepsis syndrome (SS) is associated with depressed PAF acetylhydrolase, the enzyme responsible for the degradation of platelet activating factor. PAF acetylhydrolase is in a large part produced by macrophages, whose inadequate activation with haemophagocytosis is frequent in patients with SS. The aim of this study was to test the hypothesis that PAF acetylhydrolase levels could be affected in these critically ill patients, because of the large amounts produced by activated macrophages in vitro and in vivo in animal models. The levels of serum PAF acetylhydrolase were assessed in 90 SS patients, who were divided into three groups: patients with (n = 34) or without haemophagocytosis (n = 31), and patients without thrombocytopenia (n = 25) who were used as a control group. The number of organ dysfunctions was matched between patients with haemophagocytosis and controls. Normal reference values were obtained in 59 randomly selected blood donors. Circulating levels of PAF acetylhydrolase were significantly (p = 0.0001) decreased in patients with SS (57+/-3 nmol/ml/min, n = 90) when compared with healthy subjects (69+/-3 nmol/ml/min, n = 59). PAF acetylhydrolase levels were greater in the presence of a haemophagocytosis but without statistical significance (64.2+/-6.5 vs. 50.1+/-2.8:p = 0.25). Despite the fact that macrophagic activation stimulates the in vitro release of PAF acetylhydrolase, no difference was found between patients with or without haemophagocytosis. The mechanism and the role of the PAF acetylhydrolase reduction in SS patients remain to be determined
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