Successful myomectomy during pregnancy

Leiomyoma is the most common benign tumor of the uterus and could complicate pregnancy. Here we present a case of leiomyoma in a nullipara women at the 24 th week of gestation complained of abdominal pain and nausea which was not responding to conservative therapies. A laparotomy was done and a 30*20 cm mass was resected from the uterus. She had a normal term delivery after the operation

Recurrent ectopic pregnancy in the fallopian tubes

Here, we present a case with several episodes of ectopic pregnancy in the fallopian tubes, which was treated by medical and surgical methods, and followed for two years until it ended in a term successful delivery

Modifiable risk of breast cancer in Northeast Iran: Hope for the future. a case-control study

Background: Breast cancer is the most common cancer in women. Its prevalence is increasing annually by 2. The determination of modifiable risk factors has been the subject of various studies. The aim of this study was to determine risk factors of breast cancer in women in Golestan Province. Patients and Methods: This case-control study was conducted among women with breast cancer recorded in the cancer registry system between 2004 and 2006 (n = 134), and their agematched healthy neighbors (n = 133). Data were statistically analyzed. Results: Age at marriage, menarche and pregnancy, breast feeding, positive family history, marital status, and educational level were not significantly correlated with risk of breast cancer, but age at menopause (< 46.6 years) was significantly correlated (95 confidence interval 1.15-7.37; p = 0.021). Live births, still births, and infant deaths were not significantly different between the 2 groups. For other variables, such as smoking history, no odds ratio was calculated. Conclusion: Results show that there is no significant correlation between variables and risk of breast cancer in our population, except for age at menopause. A large cohort study is recommended. © 2011 S. Karger GmbH, Freiburg

Opium as a fatal substance

Objective: Poisoning does the most serious damages in pediatrics. In the northeast of Iran (Golestan province), opium is used widely for symptomatic therapy of routine illnesses in young children by parents. In the present study, opium toxicity was assessed in young children referred to pediatric centers in our area. Methods: This survey was done as a prospective cross-sectional study. At first, a pilot study was undertaken to estimate the condition of opium intoxicated children and evaluate the validity of questionnaire. We collected data in collaboration with committee of Adverse Drug Reactions (ADR) in Golestan Province. All members of ADR committee in pediatric centers were trained to complete questionnaires in referred or admitted children under-5-year. Data was entered into computer and analyzed by Chi-square and Fisher exact test. Results: In this survey, 67 opium-intoxicated children were recruited. Minimum age of the cases was 6 days and maximum 5-year. Uneducated mothers, in most cases, gave opium to the child. Most of them were from the low socio-economic level. Ethnic was disparity was observed. Four deaths occurred. Conclusion: As the results showed, opioids are dangerous in pediatric population, especially under 5-year. Respiratory depression, bradypnea, coma and death are the serious outcomes of opium toxicity in pediatrics. Such a practice of unrestricted use of opium contributes to children mortality and so it is essential to launch educational programs. © 2008 Dr. K C Chaudhuri Foundation

Wild lettuce (Lactuca virosa) toxicity

Wild lettuce (Lactuca virosa) can cause toxic effects when eaten. Wild lettuce grows in the north of Iran and some natives consume it unaware of its adverse side effects. We describe eight patients with manifestations of wild lettuce toxicity, admitted to a general hospital affiliated to the Golestan University of Medical Sciences. All the patients recovered (although one had to spend 48 h in the intensive care unit) and no chronic complications were reported. A clinical suspicion of toxicity caused by wild lettuce intake and an accurate history formed the basis of the diagnosis. Conservative treatment, vital sign monitoring, control of patient intake and output, and reducing patient agitation provided the basis for treatment

Evaluation of diagnostic value of PH in differentiation of pleural effusion

چکیده: زمینه و هدف: PH مایع جنب یکی از عمده ترین شاخص ها در تعیین نوع افیوژن‌های پلور و تصمیم‌گیری برای نصب Chest-tube ‌بوده و معیاری حساس برای تعیین سرنوشت یک پلورزی است. این مطالعه با هدف تعیین ارزش تشخیصی میزان PH در افتراق مایع پلور انجام شد. روش بررسی: این مطالعه با روش تشخیصی و تکنیک مشاهده ای روی 350 نفر بیمار مبتلا به افیوژن پلور مراجعه کننده به بیمارستان های تحت پوشش دانشگاه علوم پزشکی شهید بهشتی انجام گردید. مقدار cc 30-20 مایع پلور بیماران اخذ و مقادیر پارامترهای قند، پروتئین، گلبول سفید و لیپوپروتئین با دانسیته بالا (HDL) و اندازه گیری شد. حساسیت، اختصاصیت، ارزش پیشگویی کننده مثبت و منفی و کارآیی اندازه گیری هر یک از این فاکتورها در مقایسه با چهار فاکتور دیگر در افتراق افیوژن های پلور به اگزوداتیو و ترانسوداتیو بررسی و محاسبه گردید. یافته ها: از 350 نمونه مایع پلور 266 نفر اگزوداتیو و 84 نفر ترانسوداتیو بودند. بر اساس نوع مایعات تعیین شده حساسیت، ارزش پیش گویی کننده مثبت، کارآیی، ارزش پیش گویی کننده منفی و PH به ترتیب 75، 72، 61، 26 به دست آمد. نتیجه گیری: با توجه به اینکه هنوز در اکثر بخش‌ها توصیه به انجام تمامی تست‌ها جهت افتراق افیوژن‌های پلور می‌گردد و این می‌تواند علاوه بر هزینه و صرف زمان دارای خطا و اشتباه باشد به نظر می‌رسد که تعیین میزان PH تنها جهت افتراق افیوژن‌های پلور بدور از هرگونه خطا و اشتباه باشد

Serum level of lactate dehydrogenase, homocystein, hemoglobin and platelet in preeclampsia

Objectives: Pre-eclampsia affects approximately 5-8% of pregnant women. The aim of this study was to compare the serum level of Lactate dehydrogenase (LDH), Homocystein, Hemoglubin and platelet in pregnant women diagnosed as pre-eclampsia and a normal group in Gorgan city, Northeastern Iran from 2007-2008. Methodology: In this case control study, 50 cases of pre-eclampsia were compared with the control group women hospitalized in Dezyani hospital. Pre-eclampsia criteria were: Blood pressure more than or equal to 140/90 mm hg and Proteinuria greater or equal to 300 mg/ 24 hours urine sample in the third trimester. Hemoglobin, platelet, LDH and hemocystein were measured. Data were analyzed by the mean of SPSS-14 program & Chi-2 or t-student were used. Results: The difference of BMI and family incomes was significant between two groups (P-value0.01). Hemocystein level was more than normal range in five patients with pre-eclampsia (P-value<0.001). Conclusions: In this study, hemocystein level was significantly higher in pre-eclampsia patients but LDH, hemoglobin and platelet level had no significant difference

Lymphomas in Golestan province of Iran: Results of a population-based cancer registry

Introduction: Malignancies of lymphoid cells can be divided into Hodgkin and non-Hodgkin lymphomas (NHL) on the basis of pathologic features, clinical manifestations and treatment. In this paper we present data on lymphomas in Golestan province, in the northeast of Iran, during 2004-2006, using three years results of the Golestan population-based cancer registry (GPCR), a voting member of the International Association of Cancer Registries (IACR). Methods: GPCR started collecting data on all cancers from all public and private diagnostic and therapeutic centers (hospitals, specialist physicians' offices, pathology, laboratory, and imaging centers) of Golestan province in 2004. Here, we used the Iranian national census data to identify the population characteristics of this geographical area. The last census was done in 2006 and the next one will be done in 2011. The population data for years between the national census intervals are retrieved from provincial census done annually by health deputy of Golestan University of Medical Sciences (GOUMS). Results: A total of 5,076 cancer cases were diagnosed in the GPCR between 2004 and 2006. Of these, 237 (4.67 %) were lymphomas, among the ten top cancers of this area, the patients having a mean (±SD) age of 45.2 (±20.9) years. The number of cases, frequency, age specific rates, crude rates and age standardized incidence rates (ASR) (per 100,000 personyears) for lymphomas in males and females are presented. Conclusion: It could be concluded that according to available therapies for HL and NHL, the outcome of the patients could be improved in this area, due to the better diagnostic and therapeutic methods now available