9 research outputs found
Percentages of platelet-monocyte (A) and platelet-neutrophile (B) complexes in FFR-negative and FFR-positive patients, identified by presence of platelet marker CD42b on monocytes and neutrophils. Lines indicate median values with interquartile range.
<p>Percentages of platelet-monocyte (A) and platelet-neutrophile (B) complexes in FFR-negative and FFR-positive patients, identified by presence of platelet marker CD42b on monocytes and neutrophils. Lines indicate median values with interquartile range.</p
Cumulative expression of P-selectin after stimulation with ADP (A), TRAP (B), CRP (C) and Iloprost with substimulatory ADP (D). Lines indicate median values with interquartile range.
<p>Cumulative expression of P-selectin after stimulation with ADP (A), TRAP (B), CRP (C) and Iloprost with substimulatory ADP (D). Lines indicate median values with interquartile range.</p
Maximal expression of P-selectin after stimulation with ADP (A), TRAP (B), CRP (C) and Iloprost with substimulatory ADP (D). Lines indicate median values with interquartile range.
<p>Maximal expression of P-selectin after stimulation with ADP (A), TRAP (B), CRP (C) and Iloprost with substimulatory ADP (D). Lines indicate median values with interquartile range.</p
Platelets per monocyte (A) and neutrophil (B) measured by MFI of CD42b. Lines indicate median values with interquartile range.
<p>Platelets per monocyte (A) and neutrophil (B) measured by MFI of CD42b. Lines indicate median values with interquartile range.</p
Conversion of dose-response curve into area under the curve.
<p>In order to compare total platelet reactivity between patients, we derived the area under the curve from each dose response curve. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p
Platelet reactivity related to macrophage levels.
<p>Comparison of the AUC after ADP stimulation between low (n = 67) versus high macrophage levels in atherosclerotic carotid plaques (n = 24). Grey bars represent means with standard deviations. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p
Histology of macrophage levels in atherosclerotic carotid plaques.
<p>Macrophage staining (brown), nucleus staining with haematoxylin (blue). (<b>a</b>) Low macrophage levels (40× magnification). (<b>b</b>) Higher magnification of the indicated area in (a) (100× magnification). (<b>c</b>) High macrophage levels (40× magnification). (<b>d</b>) Higher magnification of the indicated area in (c) (100× magnification).</p
Platelet reactivity related to platelet-monocyte complexes.
<p>Comparison of the AUC after ADP stimulation between low (n = 122) versus high levels of platelet-monocyte complexes (n = 122). Grey bars represent medians with interquartile ranges. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p
Baseline characteristics.
<p>Continuous values are expressed as mean ± standard deviation (unless specified otherwise). Categorical values are expressed as number of total (percentage).</p><p>CG = Cockroft-Gault, CEA = carotid endarterectomy, IQR = interquartile range.</p