The Effect of Fracture on Quality of Life in Postmenopausal Osteoporotic Women - Original Investigation

Prolonged human life span and amelioration of the current health conditions brings up the risk of fracture related to osteoporosis as an important medical problem. In this study, we aim to study the effect of fracture on quality of life with 29 postmenopopausal women with fracture and 33 without osteoporotic fracture. Demographic data, height, maximum height, body weight, body weight at age 25, localization of fracture of the patients were recorded. All of the patients' bone mineral densities (BMD) were evaluated with Dual energy X ray absorbtiometri (DXA). For evaluating quality of life Short Form 36 (SF 36) survey was used. In this study there were no statistical differences between the 2 groups when their age, menarc age, menopause age, number of pregnancies, height, body weight, maximum height and body weight at age 25 were compared. There was statistical difference between the groups in their shortening of height. When BMD levels were compared with DXA it was noted that the T scores at femur neck area and lowest area of BMD were statistically lower in the group with fractures; however there was no statistical difference in T scores of L2-L4. When we compared the quality of life of the 2 groups using SF 36 there was no statistical difference. (Osteoporoz Dünyasından 2006; 12 (2): 31-34

Osteoporosis in Children with Cerebral Palsy

Immobilization, poor feeding skills and inadequate calcium intake, limited sun light exposure and anticonvulsant medication in children with cerebral palsy (CP) predisposes these children to osteoporosis. The aim of this study was to determine the bone mimeral density (BMD) in our group of children with CP, compare it with the control group and investigate the relationship of BMD with probable risk factors of osteoporosis. Twenty-three children with CP (mean age 9,15 ± 4,13 years, range 5-17 years) and 15 healthy children ( mean age 8,13 ± 2,82) were included in the study. The patient group was especially investigated for anticonvulsant medication, dietary habits, sunlight exposure and daily duration of ambulation. In physical examination clinical type of CP, muscle tonus and type of ambulation were recorded. The BMD of the children was measured with dual x- ray absorptiometry (DEXA Lunar) in lumbar region and total body. Lomber and total BMD in children with CP were lower than that of controls, but this result was not statistically significant. In the patient group BMD in the arms was higher (p< 0.05). Lomber and total BMD were lower in children with inadequate dietary calcium intake (p< 0.05). We concluded that osteoporosis and related risk of fractures should be taken into consideration when dealing with CP and more studies with larger groups of children should be planned

Central Post-Stroke Pain in Stroke Patients: Incidence and the Effect on Quality of Life

Abstract Objective: The aim of this study was to investigate the incidence of central post-stroke pain in stroke patients and the effect of central post-stroke pain on quality of life. Material and Methods: One hundred stroke patients (47 women, 53 men), admiting to the inpatient rehabilitation clinic or stroke outpatient followup clinic were included in this cross-sectional study. Patients with aphasia, intermediate and advanced levels of cognitive disorder, subarachnoid hemorrhage, arteriovenous malformation, tumor, traumatic brain injury and multiple sclerosis causing hemiplegia, having neuropathic pain and complex regional pain syndrome in the history were excluded. central pain was evaluated with Leeds assessent of neuropathic symptoms and signs pain scale (LANSS), quality of life was assessed with the Nottingham Health Profile. Results: The mean age of the patients were 60.27±11.59 years, stroke duration was 14.65 months (range 2-124). Hemiplegia was on the right side in 35 cases, left side in 65 cases. 77 patients had ischemic, 23 patients had hemorrhagic etiology. Twelve patients had central post-stroke thalamic pain. Central pain was related with a significant difference in the pain parameter of Nottingham Health Profile (NHP)(p=0.001). Conclusion: The central post-stroke pain is a complication that should not be ignored because it is not rare and has negative impact on the quality of life of patients with stroke

The effect of vacuum and modified atmosphere packaging on shelf - life of fish

Beslenme açısından değerli bir gıda olan balık, tüketilinceye kadar uygun koşullarda tutulmadığı takdirde hızlı bir şekilde bozulabilmekte ve sağlık için tehlikeli hale gelebilmektedir. Balıkların raf ömürleri atmosferik oksijen, depolama sıcaklığı ve aerobik mikroorganizmaların gelişimi gibi nedenler dolayısıyla kısıtlanmaktadır. Bu faktörlerin her biri tek başına veya beraber renk, tat ve kokuda değişiklikler meydana getirerek kalitede bozulmalara sebep olmaktadır. Bunun dışında özellikle balıklarda yüksek oranda bulunan histidin aminoasidinin dekarboksilasyonu sonucu oluşan ve biyojenik bir amin olan histamin, potansiyel bir tehlike oluşturmakta ve zehirlenmelere yol açmaktadır. Bu derlemede günümüzde gıdaları muhafaza etmek amacıyla yaygın olarak kullanılan vakum ve modifiye atmosferde paketlemenin (MAP), balıklarda oluşabilen histamin düzeyine ve bununla beraber balıkların raf ömrü üzerine etkisinin incelenmesi amaçlanmıştır.Fish, which has nutritive value, can be spoilt rapidly and become harmful unless it is kept under appropriate conditions. Shelf - life of fish is restricted due to the consequence of atmospheric oxygen, storing temperature and the development of aerobic micro-organisms. Each of these factors, alone or together, causes damage in quality by making changes in colour, taste and smell. In addition to this, histamine, which is constituted as a result of decarboxylation of hystidine aminoacid - particularly found heavily in fish - and also a biogenic anime, is a potential danger and causes poisoning. In this compilation, it is aimed to analyze the effect of vacuum and modified atmosphere packaging (MAP), which is commonly used for keeping the food products today on the level of histamine that may be found in fish and shelf - life of fish, as well

Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients

Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients and compare it with the same age and sex matched healthy volunteers. Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were included in the study. Serum 25-hydroxy vitamin D levels were compared between the two groups; also the relationship of disease activity and 25-hydroxy Vitamin D levels were examined in patients with psoriasis. Probability values of <0.05 were considered as statistically significant. Results: The mean age of patients with psoriasis and control groups were not statistically different (p>0.05). In addition, the mean 25-hydroxy vitamin D levels were not significantly different among the two groups (p>0.05). 25-hydroxy vitamin D levels were no significantly different in patients with and without psoriatic arthritis (p>0.05). No significant correlation was found between psoriasis area severity index PASI values, age or 25-hydroxy vitamin D levels (p>0.05). Conclusion: The low levels of vitamin D in population is reported to be common. In our study, similar low vitamin D levels were found in healthy volunteers and premenopausal psoriasis patients. Serum 25-hydroxy vitamin D levels were not correlated with disease activity in patients with psoriasis. Correlation between psoriasis, disease activity and vitamin D levels should be investigated in larger populations. (Turkish Journal of Osteoporosis 2014;20: 93-7