Platelet signaling--blood's great balancing act

The antagonistic balance between CalDAG-GEFI and RASA3 signaling is critical for the fine-tuning of platelet adhesiveness, both in the circulation and at sites of vascular injury

Platelets at the vascular interface

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Panorama imaging for image-to-physical registration of narrow drill holes inside spongy bones

Image-to-physical registration based on volumetric data like computed tomography on the one side and intraoperative endoscopic images on the other side is an important method for various surgical applications. In this contribution, we present methods to generate panoramic views from endoscopic recordings for image-to-physical registration of narrow drill holes inside spongy bone. One core application is the registration of drill poses inside the mastoid during minimally invasive cochlear implantations. Besides the development of image processing software for registration, investigations are performed on a miniaturized optical system, achieving 360° radial imaging with one shot by extending a conventional, small, rigid, rod lens endoscope. A reflective cone geometry is used to deflect radially incoming light rays into the endoscope optics. Therefore, a cone mirror is mounted in front of a conventional 0° endoscope. Furthermore, panoramic images of inner drill hole surfaces in artificial bone material are created. Prior to drilling, cone beam computed tomography data is acquired from this artificial bone and simulated endoscopic views are generated from this data. A qualitative and quantitative image comparison of resulting views in terms of image-to-image registration is performed. First results show that downsizing of panoramic optics to a diameter of 3mm is possible. Conventional rigid rod lens endoscopes can be extended to produce suitable panoramic one-shot image data. Using unrolling and stitching methods, images of the inner drill hole surface similar to computed tomography image data of the same surface were created. Registration is performed on ten perturbations of the search space and results in target registration errors of (0:487 ± 0:438)mm at the entry point and (0:957 ± 0:948)mm at the exit as well as an angular error of (1:763 ± 1:536)°. The results show suitability of this image data for image-to-image registration. Analysis of the error components in different directions reveals a strong influence of the pattern structure, meaning higher diversity results into smaller errors. © 2017 SPIE

Preparations for successful vineyard mechanization (2011)

"New 3/11/Web.""University of Missouri Extension.""Agriculture.""The authors extend sincere appreciation to Dr. Terry Bates, Greg Berg, Nick Pehle, Dana Merrill and Gene Cowherd for reviewing this publication. They also gratefully acknowledge financial support from the Viticulture Consortium East and the Missouri Wine and Grape Board.

Jung e o tempo de Eranos. Do sentido espiritual e pedagógico do Círculo de Eranos.

Este estudo desenrola-se na perspetiva da história das ideias e pretende dar a conhecer, num primeiro momento, a natureza e a importância interdisciplinar do Círculo de Eranos (Eranoskreis) nos estudos da simbólica tradicional, da imaginação e do imaginário. Num segundo momento, falaremos da figura de Carl Gustav Jung (1875-1961) e do seu contributo na constituição, afirmação e irradiação do Círculo de Eranos desde 1933 até 1951. Numa palavra, pretende-se dar a conhecer o seu contributo, na base de um novo humanismo, à missão do Círculo de Eranos e não propriamente apresentar e discutir as temáticas das catorze conferências que proferiu ao longo da sua participação nas sessões de Eranos. Finalmente, e é já o nosso terceiro momento, assinalaremos o “novo humanismo” que parece emergir da aventura interdisciplinar do Eranoskreis

The seroprevalence and salivary shedding of herpesviruses in Behcet's syndrome and recurrent aphthous stomatitis

This journal is published under the terms of the Creative Commons Attribution-NonCommercial 4.0 Unported licens

Feature tracking for automated volume of interest stabilization on 4D-OCT images

A common representation of volumetric medical image data is the triplanar view (TV), in which the surgeon manually selects slices showing the anatomical structure of interest. In addition to common medical imaging such as MRI or computed tomography, recent advances in the field of optical coherence tomography (OCT) have enabled live processing and volumetric rendering of four-dimensional images of the human body. Due to the region of interest undergoing motion, it is challenging for the surgeon to simultaneously keep track of an object by continuously adjusting the TV to desired slices. To select these slices in subsequent frames automatically, it is necessary to track movements of the volume of interest (VOI). This has not been addressed with respect to 4DOCT images yet. Therefore, this paper evaluates motion tracking by applying state-of-the-art tracking schemes on maximum intensity projections (MIP) of 4D-OCT images. Estimated VOI location is used to conveniently show corresponding slices and to improve the MIPs by calculating thin-slab MIPs. Tracking performances are evaluated on an in-vivo sequence of human skin, captured at 26 volumes per second. Among investigated tracking schemes, our recently presented tracking scheme for soft tissue motion provides highest accuracy with an error of under 2.2 voxels for the first 80 volumes. Object tracking on 4D-OCT images enables its use for sub-epithelial tracking of microvessels for image-guidance. © 2017 SPIE