Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future

Purpose Age-related macular degeneration (AMD) is a frequent, complex disorder in elderly of European ancestry. Risk profiles and treatment options have changed considerably over the years, which may have affected disease prevalence and outcome. We determined the prevalence of early and late AMD in Europe from 1990 to 2013 using the European Eye Epidemiology (E3) consortium, and made projections for the future. Design Meta-analysis of prevalence data. Participants A total of 42 080 individuals 40 years of age and older participating in 14 population-based cohorts from 10 countries in Europe. Methods AMD was diagnosed based on fundus photographs using the Rotterdam Classification. Prevalence of early and late AMD was calculated using random-effects meta-analysis stratified for age, birth cohort, gender, geographic region, and time period of the study. Best-corrected visual acuity (BCVA) was compared between late AMD subtypes; geographic atrophy (GA) and choroidal neovascularization (CNV). Main Outcome Measures Prevalence of early and late AMD, BCVA, and number of AMD cases. Results Prevalence of early AMD increased from 3.5% (95% confidence interval [CI] 2.1%–5.0%) in those aged 55–59 years to 17.6% (95%

An Assessment of the Psychometric Properties of the Brief Sensation Seeking Scale for Children

Sensation seeking is a trait that predicts a wide range of real-life risk behavior, such as substance abuse and gambling problems. Sensation seeking is often assessed with the Sensation Seeking Scale. Several adaptations of this questionnaire have been made, for example, to abbreviate it and to make it suitable for children. However, studies on sensation seeking in children are scarce. The aim of this study was to investigate sensation seeking in children (N = 158, M age = 11.4 years). The Brief Sensation Seeking Scale for Children (BSSS–C) was translated into Dutch and psychometric properties were examined. Internal consistency was high, and the factor structure showed close resemblance with previous research. Test–retest and split-half reliabilities were acceptable, as was convergent validity with self-reported symptoms of psychopathology (attention problems and aggressive behavior). Construct validity was adequate, with more sensation seeking in boys than in girls. No effects of age were found. To sum up, sensation seeking can be measured in children in a valid and reliable way. The correlation of sensation seeking with high-risk behaviors emphasizes the importance of assessment early in development

Do initial concentration and activated sludge seasonality affect pharmaceutical biodegradation rate constants?

Biodegradation rates of nine pharmaceuticals were obtain in batch experiments inoculated with summer and winter activated sludge spiked with different chemical concentrations. The effect of different chemical structures, concentrations and sludge seasonality on biodegradation rate constants was teste

Water Hyacinth’s Effect on Greenhouse Gas Fluxes: A Field Study in a Wide Variety of Tropical Water Bodies

Water hyacinth is able to sequester large amounts of carbon dioxide (CO2) in wetlands. At the same time, the high production of organic matter combined with the plant’s capacity to limit the diffusion of oxygen from the atmosphere into the water creates favorable conditions for the production of methane (CH4). The combination of these mechanisms challenges the prediction of water hyacinth’s net effects on greenhouse gas (GHG) emissions. To unravel the impact of water hyacinth on GHG fluxes, we performed an extensive fieldwork study encompassing 22 sites dominated by water hyacinth in the Pantanal and Amazon during two different seasons. The highest CH4 emissions from water hyacinth beds occurred in shallow systems where sediment rooting enabled plant-mediated CH4 transport (307 ± 407 mg CH4 m−2 day−1 in waters shallower than 1 m, as opposed to 6.1 ± 10.6 mg CH4 m−2 day−1 in deeper waters). When CO2 uptake rates are added to the GHG budget (in terms of global warming potential), the water bodies were usually a GHG sink (− 5.2 ± 10 gCO2 eq m−2 day−1). The strength of the sink is highest in deeper systems where even a low water hyacinth coverage may already offset open water emissions. This dual effect of strong CO2 uptake—and at least temporal carbon storage in biomass—in combination with a high CO2–to-biomass-to-CH4 (and possibly back to CO2) conversion highlights the necessity to include vegetation characteristics in relation to depth when estimating GHG fluxes for tropical wetlands