170 research outputs found

    Analysis of Serum Th2 Cytokines in Infants with Non-IgE Mediated Food Allergy Compared to Healthy Infants

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    Background: The aim of this study is to assess the serum values of IL-4, IL-5, IL-10, and IL-13 in a group of infants with non-IgE mediated food allergies treated with a hydrolyzed formula and compare them with a group of healthy peers. Methods: A total of 53 infants aged 1 to 4 months, of which 34 with non-IgE mediated food allergies and 19 healthy infants were enrolled in this study. Infants were eligible if they had gastrointestinal symptoms of food allergy and needed to switch from their initial formula to hydrolyzed formulas with an improvement of symptoms. Controls were fed with either breastmilk or standard formula. Blood samples were taken within one week of a special diet for cases. Interleukinsin in peripheral blood was detected and analyzed using the real-time PCR MAMA method. Fecal calprotectin was evaluated using a quantitative assay. Results: Values of IL-4 and IL-13 were significantly higher in the non-IgE food allergy group compared to the control group (p < 0.05), while IL-5 and IL-10 were significantly lower than the control group (p < 0.05). Fecal calprotectin in the non-IgE food allergy group was significantly higher compared to the control group (p < 0.05). Conclusion: This study provides a theoretical basis that Th2 cytokine expression in infants with a non-IgE mediated food allergy is significantly different than in healthy infants; this finding supports the use of early dietetic treatment with hydrolyzed formulas

    Adubação mineral do amendoim. I. Ensaio em solos das séries Itaguaí e Ecologia

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    It is reported a research work done with the objetive to investigate the effect of N, P, K, Ca and Mg and its interact on Peanut Crop (Arachis hypogaea L.). The work was done in soils classified as Itaguai and Ecologia series, covering most of the Km 47 area and Baixada de Sepetiba. In the studied soils, relating to the Itaguai series, it was found the lime effect, being that in one of the soils of this series was also found a favorable effect of the magnesium in increasing the peanut production. It was still found the negativeness of potassium in one of the studied soils of Itaguai series, when added lime, magnesium and nitrogen it neutralized the beneficial action of these minerals in the productivity. In the soils of Ecology series, only the effect of magnesium was statistically significant. However the magnesium showed positive reaction when added to the phosphorus and to the potassium, while the lime showed negative reaction in the production, though without statistic significance.É relatada uma pesquisa realizada com o objetivo de estudar o efeito de N, P, K, Ca e Mg e suas interações sobre a cultura do amendoim (Arachis hypogaea L.). Os trabalhos foram instalados em solos mapeados como das séries Itaguaí e Ecologia, dominantes na área do Km 47 e Baixada de Sepetiba. Nos solos estudados, pertencentes à série Itaguaí, foi positivado o efeito da cal, sendo que em um dos solos desta série houve, também, efeito favorável do magnésio no aumento da produção do amendoim. Sendo solos de uma mesma série, parece estranho o fato mencionado mas é necessário esclarecer que, na série Itaguaí, existem vários tipos de solos cujas reações divergem quanto às adubações e, além do mais, que as respostas do amendoim aos fertilizantes não são constantes, variando muito, mesmo em solos do mesmo tipo. Foi constatada, ainda, a negatividade do potássio num dos solos estudados da série Itaguaí, pois este macronutriente neutralizou, quando junto à cal, ao magnésio e ao nitrogênio, a ação benéfica destes, na produtividade. No solo da série Ecologia, somente o efeito do magnésio foi estatisticamente significativo, mas o magnésio, junto ao fósforo e ao potássio, mostrou reação positiva, enquanto que a cal mostrou reação negativa na produção, embora sem significação estatística
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