1 research outputs found
Genetic admixture patterns in Argentinian Patagonia
As in other Latin American populations, Argentinians are the result of the admixtureamongst different continental groups, mainly from America and Europe, and to a lesserextent from Sub-Saharan Africa. However, it is known that the admixture processes did notoccur homogeneously throughout the country. Therefore, considering the importance foranthropological, medical and forensic researches, this study aimed to investigate the populationgenetic structure of the Argentinian Patagonia, through the analysis of 46 ancestryinformative markers, in 433 individuals from five different localities. Overall, in the Patagoniansample, the average individual ancestry was estimated as 35.8% Native American(95% CI: 32.2?39.4%), 62.1% European (58.5?65.7%) and 2.1% African (1.7?2.4%). Comparingthe five localities studied, statistically significant differences were observed for theNative American and European contributions, but not for the African ancestry. The admixtureresults combined with the genealogical information revealed intra-regional variationsthat are consistent with the different geographic origin of the participants and their ancestors.As expected, a high European ancestry was observed for donors with four grandparentsborn in Europe (96.8%) or in the Central region of Argentina (85%). In contrast, theNative American ancestry increased when the four grandparents were born in the North(71%) or in the South (61.9%) regions of the country, or even in Chile (60.5%). In summary,our results showed that differences on continental ancestry contribution have different originsin each region in Patagonia, and even in each locality, highlighting the importance ofknowing the origin of the participants and their ancestors for the correct interpretation andcontextualization of the genetic information.Fil: Parolin, Mar铆a Laura. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Toscanini, Ulises Faustino. Fundaci贸n Favaloro; ArgentinaFil: Vel谩zquez, Irina Florencia. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Llull, Cintia. Fundaci贸n Favaloro; ArgentinaFil: Berardi, Marisa Gabriela. Fundaci贸n Favaloro; ArgentinaFil: Holley Reguil贸, Juan Alfredo. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Tamburrini, Camila. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Avena, Sergio Alejandro. Universidad Maim贸nides. 脕rea de Investigaciones Biom茅dicas y Biotecnol贸gicas. Centro de Estudios Biom茅dicos, Biotecnol贸gicos, Ambientales y de Diagn贸stico; Argentina. Universidad de Buenos Aires. Facultad de Filosof铆a y Letras. Instituto de Ciencias Antropol贸gicas; Argentina. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas; ArgentinaFil: Carnese, Francisco Raul. Universidad de Buenos Aires. Facultad de Filosof铆a y Letras. Instituto de Ciencias Antropol贸gicas; ArgentinaFil: Lanata, Jose Luis. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Patagonia Norte. Instituto de Investigaciones en Diversidad Cultural y Procesos de Cambio. Universidad Nacional de R铆o Negro. Instituto de Investigaciones en Diversidad Cultural y Procesos de Cambio; ArgentinaFil: Carnero, Noela S谩nchez. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Arce, Lucas Federico. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Basso, Nestor Guillermo. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Centro Cient铆fico Tecnol贸gico Conicet - Centro Nacional Patag贸nico. Instituto de Diversidad y Evoluci贸n Austral; ArgentinaFil: Pereira, Rui. Universidad de Porto; PortugalFil: Gusm茫o, Leonor. Universidade do Estado de Rio do Janeiro; Brasil. Universidad de Porto; Portuga