Treatment And Mechanisms Of Action Of Some Medicinal Plants For Managing Hypertension

Elevated blood pressure is officially referred to as hypertension. It's dangerous because it puts undue strain on the heart and encourages atherosclerosis, which raises the risk of heart disease and stroke. In addition to these conditions, hypertension can cause blindness, kidney damage, and congestive heart failure. Conventional antihypertensive drugs usually have a lot of side effects. Because of their greater body compatibility and less side effects, Herbal remedies are utilised in primary care by between 75 and 80 percent of the world's population who live in impoverished nations. In the past thirty years, a great deal of study has been conducted on native plants that have hypotensive and hypertensive therapeutic properties. While certain medicinal plants have been shown to have antihypertensive and hypotensive properties, others have not. Modern medicine should be integrated with the knowledge of Ayurveda, and more studies are required to verify the effectiveness and elucidate the safety profile of herbal remedies for lowering blood pressure. People with cardiovascular disorders—which can be caused by diseases of the heart and blood vessels are treated using medicinal plants. Hypertension raises the risk of a heart attack and stroke, which also damages the heart and accelerates atherosclerosis. These disorders are treated with a variety of drugs, however standard antihypertensive medications frequently have several side effects. Active substances found in medicinal plants can be used to treat hypertension since they have pharmacological and preventative properties. An overview of medicinal plants with hypotensive or antihypertensive properties can be found in this article

Direct Z-Scheme BiOCl/α-Fe2O3Heterojunction: A Pathway to Enhanced Photoelectrochemical Water Splitting

Inadequate solar absorption and inefficient charge separation are the primary factors that limit the conversion efficiency in photoelectrochemical water-splitting systems.In this work, a BiOCl/α-Fe2O3(BFE) heterostructure was synthesized using a direct deposition technique, varying the loading of α-Fe2O3nanoparticles on BiOCl nanosheets to optimize its photoelectrochemical (PEC) properties.The well-dispersed α-Fe2O3nanoparticles on the BiOCl surface enhance light absorption in the visible region while accelerating charge separation efficiency.The optimized BFE2 heterostructure exhibits a photocurrent density that is 2.5 times higher than pure BiOCl and 87 times greater than α-Fe2O3, demonstrating its superior photoelectrochemical performance.The charge carrier lifetime under continuous light irradiation reveals that BFE2 exhibits a higher value of approximately 3.97 seconds, indicating an enhanced availability of free charge carriers in the optimized BFE2 heterostructure.A direct Z-scheme heterojunction is proposed to form at the BiOCl/α-Fe2O3interface, effectively facilitating charge separation and enhancing charge mobility.This work offers valuable insights into developing a simple and cost-effective approach for synthesizing BiOCl/α-Fe2O3heterostructures that significantly improve the photoresponse of BiOCl photoanodes in PEC water splitting

Nanomaterials Drug Delivery System in Herbal Formulation For Antidiabetic Activity: A Review

Diabetes, a chronic metabolic disorder, results in high blood glucose levels due to insufficient insulin production or ineffective insulin utilization. Management entails lifestyle changes, exercise, and medication adherence. Monitoring blood sugar levels, healthy eating, and medication are crucial for controlling diabetes and preventing complications. The illness, currently incurable, necessitates management strategies for regulation. Medical treatments are expensive and require long-term adherence, leading many, especially those from low-income nations, to resort to herbal remedies. However, phytocompounds, though promising, often suffer from limited bioavailability due to poor solubility, permeability, or rapid elimination. Plant nanomedicines offer a promising avenue to address these challenges and alleviate the financial strain on disadvantaged populations. Encapsulated treatments using plant extracts or antidiabetic chemicals at the nanoscale have shown promising results. Our study aims to provide a thorough examination of lipid- and inorganic-based nanoparticulate delivery systems combined with plant extracts or phytocompounds for diabetes management Our analysis will highlight both the advantages and limitations of these systems for future clinical application. Examined studies revealed that nanoparticulate formulations displayed strong antidiabetic effects at lower doses compared to individual plant extracts or phytocompounds. Additionally, nanoparticulate systems have effectively addressed the issue of low bioavailability in herbal medications, showing promise for enhanced therapeutic outcomes