14 research outputs found
Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT2A receptor gene in patients with schizophrenia responsive to antipsychotics
Advances in Coyote Optimization Algorithm: Variants and Applications
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A comprehensive survey of Crow Search Algorithm and its applications
International audienceCrow Search Algorithm (CSA) is a recent swarm intelligence optimization algorithm inspired by the social intelligent behavior of crows for hiding food. It has been widely used to solve a large variety of optimization problems in several fields and areas of research and has proved its efficiency compared to several state-of-the-art optimization algorithms available in the literature. This paper presents a comprehensive overview of Crow Search Algorithm and its new variants categorized into modified and hybridized versions. It also describes the several applications of CSA in various domains such as feature selection, image processing, scheduling, economic dispatch, distributed generation, and other engineering problems. In addition, the paper suggests some interesting research areas related to CSA enhancement, CSA hybridization, and possible new applications
Enhanced White Shark Optimization Algorithm for the Mesh Routers Placement Problem with Service Priority in Wireless Mesh Networks
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Energy Harvesting Based on SLIPT in V2V-VLC System under Atmospheric Weather Conditions
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A Survey of Channel Modeling Techniques for Visible Light Communications
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Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT<sub>2A </sub>receptor gene in patients with schizophrenia responsive to antipsychotics
Abstract Background The -1438A/G polymorphism of the 5-HT2A gene has been found to be associated with clinical response to clozapine and other second generation antipsychotics. Testing the impact of this marker on response to first generation antipsychotics (which have a lower affinity for the 5-HT2A receptor) provides the opportunity to help disentangling the two different roles that this polymorphism might have. A psychopharmacogenetic role should be detected only for antipsychotics with high affinity to the 5-HT2A receptor (therefore to second generation antipsychotics). An alternative role would imply tagging a subgroup of patients responsive to any antipsychotic, whatever their affinity, meaning that the association is more depending on non pharmacological charaterictics, such as clinical specificities. Methods A family-based sample of 100 Algerian patients with schizophrenia (according to DSM-IV criteria) and their 200 biological parents was recruited, in order to avoid stratification biases. Patients were all treated, or have been treated, by conventional antipsychotics (mainly haloperidol) for at least four weeks, at appropriate dosage. May and Dencker scale was used to distinguish responders and non responders. Results No allele of the -1438A/G polymorphism of the 5-HT2A gene was transmitted in excess (50 transmitted for 38 untransmitted) in the whole sample of patients with schizophrenia (p = .90). In contrast, a significant excess of transmission of the G allele was observed (p = .02) in the subgroup of patients with good treatment response (17 transmitted for 6 untransmitted). Conclusion Using a TDT approach, we showed that the G allele of the -1438A/G polymorphism of the gene coding for the 5-HT2A receptor was associated to schizophrenia with good response to conventional antipsychotics, although this conclusion is based on 88 informative patients only. Because previous data showed the same result with atypical antipsychotics, it can be concluded that the G allele tags a subgroup of schizophrenic patients with greater chance of improvement with antipsychotics of either type.</p
Enhanced Whale Optimization Algorithm for mesh routers placement problem in wireless mesh networks
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Enhanced Honey Badger Algorithm for mesh routers placement problem in wireless mesh networks
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Hybrid Whale Optimization Algorithm with Simulated Annealing for the UAV Placement Problem
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