Time course of parafoveal flow index (PFI) with stimulation turned on and then off.

<p>(A) Plot for individual subjects averaged from two experimental sequences. (B) Relative change from baseline averaged over all subjects. Two tailed paired t-tests with Bonferroni correction were used. * = P<.0042; ** = P<.001. The symmetric error bars in both (A) and (B) represent two standard deviation units in length.</p

Foveal flow index (FFI) representing the noise analyzed at 30 sec of baseline, stimulation and post-stimulation period.

<p>The FFI of both stimulation and post-stimulation was not significantly different from baseline. Two tailed paired t-tests with Bonferroni correction were used.</p

Experiment setup of the pattern stimulation apparatus mounted behind the OCT scan head.

<p>Size of the region (size of the checkerboard square size) was shown beside the pattern stimulation. NDF, Neutral density filter; DM, Dichroic mirror; OL, Objective lens.</p

Procedural flow chart for quantification of parafoveal blood flow.

<p>(A) Separation of retinal flow from choroidal flow using the RPE plane (dashed line) as the dividing boundary. (B) Retinal flow projected in an <i>en face</i> projection of maximum decorrelation. (C) Mask defining the region of the parafoveal retina. (D) Isolated parafoveal retinal flow following overlay of mask on the <i>en face</i> angiogram.</p

False color representation of <i>en face</i> retinal angiograms captured during the course of the experiment.

<p>Increased flow (warmer color - higher decorrelation values) was seen in the angiogram captured 30 seconds after the visual stimulation was turned on (middle) compared to baseline (left). The angiogram captured 30 seconds after stimulation was turned off (right) did not appear different from baseline.</p

cycloid_suppvideo.avi

Video of multi-volume sequence acquired with cycloid scanner

3151408.pdf

Supplemental documen

Media 5: In vivo imaging of the rodent eye with swept source/Fourier domain OCT

Originally published in Biomedical Optics Express on 01 February 2013 (boe-4-2-351

Media 2: In vivo imaging of the rodent eye with swept source/Fourier domain OCT

Originally published in Biomedical Optics Express on 01 February 2013 (boe-4-2-351

Media 1: Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers

Originally published in Biomedical Optics Express on 01 November 2012 (boe-3-11-2733