11,551 research outputs found
Quantum processes which do not use coherence
A major signature of quantum mechanics beyond classical physics is coherence,
the existence of superposition states. The recently developed resource theory
of quantum coherence allows the formalisation of incoherent operations -- those
operations which cannot create coherence. We identify the set of operations
which additionally do not use coherence. These are such that coherence cannot
be exploited by a classical observer, who measures incoherent properties of the
system, to go beyond classical dynamics. We give a physical interpretation in
terms of interferometry and prove a dilation theorem, showing how these
operations can always be constructed by interacting the system in an incoherent
way with an ancilla. Such a physical justification is not known for the
incoherent operations, thus our results lead to a physically well-motivated
resource theory of coherence. Next, we investigate the implications for
coherence in multipartite systems. We show that quantum correlations can be
defined naturally with respect to a fixed basis, providing a link between
coherence and quantum discord. We demonstrate the interplay between these two
quantities under our studied operations, and suggest implications for the
theory of quantum discord by relating the studied operations to those which
cannot create discord.Comment: 15 pages, 6 figures, comments are welcome. Revised presentation and
added Result 7. Close to published version (accepted for publication in
Physical Review X
MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport.
Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport, but the underlying mechanisms are not well understood. Here, we report our study of MAP7, a unique microtubule-associated protein that interacts with both microtubules and the motor protein kinesin-1. Structure-function analysis in rat embryonic sensory neurons shows that the kinesin-1 interacting domain in MAP7 is required for axon and branch growth but not for branch formation. Also, two unique microtubule binding sites are found in MAP7 that have distinct dissociation kinetics and are both required for branch formation. Furthermore, MAP7 recruits kinesin-1 dynamically to microtubules, leading to alterations in organelle transport behaviors, particularly pause/speed switching. As MAP7 is localized to branch sites, our results suggest a novel mechanism mediated by the dual interactions of MAP7 with microtubules and kinesin-1 in the precise control of microtubule-based transport during axon morphogenesis
The risk of misclassifying subjects within principal component based asset index.
The asset index is often used as a measure of socioeconomic status in empirical research as an explanatory variable or to control confounding. Principal component analysis (PCA) is frequently used to create the asset index. We conducted a simulation study to explore how accurately the principal component based asset index reflects the study subjects' actual poverty level, when the actual poverty level is generated by a simple factor analytic model. In the simulation study using the PC-based asset index, only 1% to 4% of subjects preserved their real position in a quintile scale of assets; between 44% to 82% of subjects were misclassified into the wrong asset quintile. If the PC-based asset index explained less than 30% of the total variance in the component variables, then we consistently observed more than 50% misclassification across quintiles of the index. The frequency of misclassification suggests that the PC-based asset index may not provide a valid measure of poverty level and should be used cautiously as a measure of socioeconomic status
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