Activité antioxydante des composés phénoliques d’huile d’olive extraite par méthode traditionnelle

L'objectif de cette etude est de determiner la teneur en composes phenoliques totaux de lfhuile dfolive de la variete Chemlal obtenue par extraction artisanale et dfen tester leur pouvoir antioxydant. La teneur phenolique a ete determinee par la methode universelle Folin-Ciocalteu, alors que lfactivite antioxydante a ete evaluee par deux methodes complementaires: le test du radical libre 2,2-diphenyl-1-picrylhydrazyl et le test du β-carotene/acide linoleique. Cette huile dfolive a montre une teneur en composes phenoliques totaux de 167,29 ± 2,71mg EAG/kg et une valeur dfIC50 egale a 25, 38 ± 0,64mg/kg par le test DPPH et une activite antioxydante relative par le test β-carotene/acide linoleique de lfordre de 67,40 ± 1,02%. Le controle positif hydroxy toluene butyle (BHT) a devoile respectivement 23,86 ± 0,14mg/kg et 95,88 ± 0,85%. Ces resultats revelent une possible utilisation de cette huile dans la lutte contre les maladies lies au stress oxydant.Mot cles : Oleaeuropea, β-carotene/acide linoleique, DPPH, variete Chemlal, regime mediterraneen

Evidence-based guidelines for supportive care of patients with Ebola virus disease.

The 2013-16 Ebola virus disease outbreak in west Africa was associated with unprecedented challenges in the provision of care to patients with Ebola virus disease, including absence of pre-existing isolation and treatment facilities, patients' reluctance to present for medical care, and limitations in the provision of supportive medical care. Case fatality rates in west Africa were initially greater than 70%, but decreased with improvements in supportive care. To inform optimal care in a future outbreak of Ebola virus disease, we employed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology to develop evidence-based guidelines for the delivery of supportive care to patients admitted to Ebola treatment units. Key recommendations include administration of oral and, as necessary, intravenous hydration; systematic monitoring of vital signs and volume status; availability of key biochemical testing; adequate staffing ratios; and availability of analgesics, including opioids, for pain relief

An experimental investigation and design of flow-conditioning devices for orifice metering

Abstract: The problems associatedwith the use of flow conditioners usually relate to their ability to remove swirl and produce a fully developed mean velocity and turbulence profiles. In the present research, the mechanism for both swirl reduction and profile correction was suspected to be related to the action occurring within the turbulent mixing zone, which occurs within the first fewdiametersdownstreamof theflowstraightener. Aflow-conditionerdevice,whichconsists of a graded perforated plate with upstream vanes and short downstream tabs mounted on the plate has been designed, and demonstrated a good performance in terms of removing swirl and producing a fully developed flow within a short distance downstream of the flow conditioner. Furthermore, the flow conditioner produces good quality results in conjunction with an orifice plate meter. The vaned plate created a self-stabilizing mechanism for the time velocity profile and turbulence structure with respect to the axial position. Furthermore, the deviation on the discharge coefficient was low at around ±0.2 per cent. Also the Zanker conditioner performs at its best when using the same design concept as the vaned plate (honeycomb followed by a perforated plate)