1 research outputs found
Automated, Capsule-Based Suzuki–Miyaura Cross Couplings
The development of an automated process for Suzuki–Miyaura
cross couplings is described, in which the complete reaction, workup,
and product isolation are effected automatically with no user involvement,
aside from loading of the starting materials and reaction capsule.
This practical and simple method was successfully demonstrated to
provide the desired biaryl products using a range of aryl bromides
and boronic acids and is also effective for the late-stage functionalization
of aryl halides in bioactive molecules