Mapping The Toronto Theatre Blogosphere

From online reviews, to live tweeting during a performance, to “liking” a production on Facebook, the blogosphere is transforming how we talk about theatre. Theatre criticism in the digital world is now a “team sport,” where audience members and artists play alongside professional critics (Fricker 49). This shift holds much potential: online critical discourse can help us develop a more diverse and inclusive picture of theatre reception and theatre-going cultures than print reviews, and expand the historical documentation of performance, which, as a vanishing art form, leaves very few traces of itself. However, the limited research in this area has yet to fully understand the role of the blogosphere in theatre ecology or how to archive the criticism found there (Collins ; Poll ; Radosavljevic). “Mapping the Toronto Theatre Blogosphere” is a new research project bringing together Dramatic Art and Computer Science students. It attempts to answer two key questions: how is the blogosphere changing how we talk about theatre, and how can we preserve the critical discourse occurring there? To answer the first question, we tracked and archived the online critical response (blog reviews, online publications, tweets, and Facebook posts) to a representative sample from the fall 2016 Toronto theatre season. Our resulting dataset was examined using a content analysis approach in order to identify which productions generated the most critical response (posts) online, the demographics of the posters (including age, gender, occupation, and ethnicity), and the purpose of the posts (including commentary on the production, socio-political commentary, endorsements, and check-ins). To answer the second question, our CS team member is developing an open-access website to archive the materials collected, which the public will be invited to use and contribute to once it is launched. Our preliminary findings suggest that the blogosphere is changing how we talk about theatre in three key ways: it is providing more coverage to new plays and plays about political or controversial subject matter; it is increasing and diversifying the participants in critical discourse, allowing women and people of colour more access into the conversations; and it is connecting discussions about theatre to other topics such as political issues and identity. Our UWill Discover presentation will summarize our findings about the Toronto theatre blogosphere and include an interactive demonstration of our database

Properties of small molecular drug loading and diffusion in a fluorinated PEG hydrogel studied by ^1H molecular diffusion NMR and ^(19)F spin diffusion NMR

R_f-PEG (fluoroalkyl double-ended poly(ethylene glycol)) hydrogel is potentially useful as a drug delivery depot due to its advanced properties of sol–gel two-phase coexistence and low surface erosion. In this study, ^1H molecular diffusion nuclear magnetic resonance (NMR) and ^(19)F spin diffusion NMR were used to probe the drug loading and diffusion properties of the R_f-PEG hydrogel for small anticancer drugs, 5-fluorouracil (FU) and its hydrophobic analog, 1,3-dimethyl-5-fluorouracil (DMFU). It was found that FU has a larger apparent diffusion coefficient than that of DMFU, and the diffusion of the latter was more hindered. The result of ^(19)F spin diffusion NMR for the corresponding freeze-dried samples indicates that a larger portion of DMFU resided in the R_f core/IPDU intermediate-layer region (where IPDU refers to isophorone diurethane, as a linker to interconnect the R_f group and the PEG chain) than that of FU while the opposite is true in the PEG–water phase. To understand the experimental data, a diffusion model was proposed to include: (1) hindered diffusion of the drug molecules in the R_f core/IPDU-intermediate-layer region; (2) relatively free diffusion of the drug molecules in the PEG-water phase (or region); and (3) diffusive exchange of the probe molecules between the above two regions. This study also shows that molecular diffusion NMR combined with spin diffusion NMR is useful in studying the drug loading and diffusion properties in hydrogels for the purpose of drug delivery applications