105 research outputs found

    Baxterization, dynamical systems, and the symmetries of integrability

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    We resolve the `baxterization' problem with the help of the automorphism group of the Yang-Baxter (resp. star-triangle, tetrahedron, \dots) equations. This infinite group of symmetries is realized as a non-linear (birational) Coxeter group acting on matrices, and exists as such, {\em beyond the narrow context of strict integrability}. It yields among other things an unexpected elliptic parametrization of the non-integrable sixteen-vertex model. It provides us with a class of discrete dynamical systems, and we address some related problems, such as characterizing the complexity of iterations.Comment: 25 pages, Latex file (epsf style). WARNING: Postscript figures are BIG (600kB compressed, 4.3MB uncompressed). If necessary request hardcopy to [email protected] and give your postal mail addres

    Family physicians' views on participating in prevention of major depression. The predictD-EVAL qualitative study

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    Background The predictD intervention, a multicomponent intervention delivered by family physicians (FPs), reduced the incidence of major depression by 21% versus the control group and was cost-effective. A qualitative methodology was proposed to identify the mechanisms of action of these complex interventions. Purpose To seek the opinions of these FPs on the potential successful components of the predictD intervention for the primary prevention of depression in primary care and to identify areas for improvement. Method Qualitative study with FPs who delivered the predictD intervention at 35 urban primary care centres in seven Spanish cities. Face-to-face semi-structured interviews adopting a phenomenological approach. The data was triangulated by three investigators using thematic analysis and respondent validation was carried out. Results Sixty-seven FPs were interviewed and they indicated strategies used to perform the predictD intervention, including specific communication skills such as empathy and the activation of patient resources. They perceived barriers such as lack of time and facilitators such as prior acquaintance with patients. FPs recognized the positive consequences of the intervention for FPs, patients and the doctor-patient relationship. They also identified strategies for future versions and implementations of the predictD intervention. Conclusions The FPs who carried out the predictD intervention identified factors potentially associated with successful prevention using this program and others that could be improved. Their opinions about the predictD intervention will enable development of a more effective and acceptable version and its implementation in different primary health care settings

    A personalized intervention to prevent depression in primary care: cost-effectiveness study nested into a clustered randomized trial

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    Background: Depression is viewed as a major and increasing public health issue, as it causes high distress in the people experiencing it and considerable financial costs to society. Efforts are being made to reduce this burden by preventing depression. A critical component of this strategy is the ability to assess the individual level and profile of risk for the development of major depression. This paper presents the cost-effectiveness of a personalized intervention based on the risk of developing depression carried out in primary care, compared with usual care. Methods: Cost-effectiveness analyses are nested within a multicentre, clustered, randomized controlled trial of a personalized intervention to prevent depression. The study was carried out in 70 primary care centres from seven cities in Spain. Two general practitioners (GPs) were randomly sampled from those prepared to participate in each centre (i.e. 140 GPs), and 3326 participants consented and were eligible to participate. The intervention included the GP communicating to the patient his/her individual risk for depression and personal risk factors and the construction by both GPs and patients of a psychosocial programme tailored to prevent depression. In addition, GPs carried out measures to activate and empower the patients, who also received a leaflet about preventing depression. GPs were trained in a 10- to 15-h workshop. Costs were measured from a societal and National Health care perspective. Qualityadjustedlife years were assessed using the EuroQOL five dimensions questionnaire. The time horizon was 18 months. Results: With a willingness-to-pay threshold of (sic)10, 000 ((sic)8568) the probability of cost-effectiveness oscillated from 83% (societal perspective) to 89% (health perspective). If the threshold was increased to (sic)30, 000 ((sic)25, 704), the probability of being considered cost-effective was 94% (societal perspective) and 96%, respectively (health perspective). The sensitivity analysis confirmed these results. Conclusions: Compared with usual care, an intervention based on personal predictors of risk of depression implemented by GPs is a cost-effective strategy to prevent depression. This type of personalized intervention in primary care should be further developed and evaluated

    Modeling Microstructure and Irradiation Effects

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    Dispositif et procédé d'analyse d'échantillon biologique par spectroscopie résolue spatialement

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    Dispositif de spectroscopie comportant :- des moyens d'irradiation destinés à irradier une zone d'irradiation d'un échantillon biologique à analyser, et- des moyens de mesure aptes à mesurer une puissance lumineuse ré-émise par des zones de mesure respectives dudit échantillon biologique,caractérisé en ce qu'il comporte des moyens de ré-injection aptes à capter une puissance lumineuse ré-émise par une zone de récupération dudit échantillon biologique, et à ré-injecter ladite puissance lumineuse captée sur une zone de ré-injection dudit échantillon biologique

    L'équation technologique et numérique en agriculture

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    National audienceSi l'avènement du numérique et de la technologie dans l'agriculture (AgTech), souvent appelé la "quatrième révolution industrielle", offre de grandes perspectives de réponse aux nombreux défis sociétaux, économiques et environnementaux auxquels est confronté la production agricole, celui-ci présente également de nombreuses menaces et limites. Ce chapitre explore les différents leviers technologique et numérique pour une transition vers une agriculture durable tout en mettant en lumière les enjeux stratégiques que sont la gestion et le partage des données, la coopération entre agriculteurs et entreprises, la formation etc

    Projection Orthogonale Dynamique (DOP). Une nouvelle méthode pour maintenir la robustesse des étalonnages multivariés en ligne. Application au suivi par spectrométrie NIR des fermentations oenologiques

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    International audienceA new method is developed to maintain the on-line robustness of multivariate calibrations against unknown influence factors, especially in the case of spectroscopy. This method is based on the use of the calibration database and the periodical on-line reference measurements with their corresponding spectra to compute an orthogonal correction. The spectra that would have been obtained in the absence of influence factor occurrence are estimated from the calibration database using the reference measurements and a kernel function. The difference between the estimated and the on-line spectra is used to compute an orthogonal projection correction of the calibration database that is used for recalibration. The originality of this method is its capability to handle different kinds of perturbations (chemical, physical, and environmental) using the original calibration database. This method was applied for on-line monitoring of alcoholic wine fermentation in the presence of temperature variations as the influence factor, where it showed a good performance for temperature variation and batch effects. Also, this method provides an on-line diagnosis tool for the spectral causes of robustness problems thus providing a basis to better understand the process in order to perform adjustments, if necessary, at an earlier stage
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