Family context and adoption of risky lifestyles: a study of English adolescents

This chapter presents the results of our empirical analysis using the recent data from the Longitudinal Survey of Young People in England (LSYPE), which is a panel study of young people aged between 13 and 14 in 2004 that is annually repeated. We develop an economic-theoretical framework with applied health econometric methods and use binary regression models to explain the probability of reporting a risky form of lifestyle at age 18 to 19. We consider seven risky forms of lifestyles, namely early sexual intercourse, teenage parenthood, early smoking, alcohol use, frequency of getting drunk, cannabis smoking and drug use. We undertake a hierarchical explanatory analysis where we include a larger vector of independent variables at each of the three steps of the analysis. This multi-step analysis enables us to understand the underlying mechanisms of the influence of family structure, especially lone-parent family, on the likelihood of adopting a range of unhealthy lifestyles in adolescence and whether family structure has a direct effect on those lifestyles, or an indirect effect, through its influence on other adolescents’ social characteristics

Long-term effect of teenage birth on earnings: Evidence from a British cohort study

We use data from the 1970 British Cohort Study and evaluate the effect of teenage motherhood on hourly earnings at age 30, 34, 38, and 42 using alternative non-experimental estimation methods including linear regression, matching methods, and Heckman sample selection models. We conclude that teenage motherhood has a significant negative long-term effect on hourly wages. At age 42, teenage mothers earn 12% less than other women and 29% less than women who have not had any children. When compared to non-teenage mothers, the pay penalty reduces over time and becomes insignificant on the long term

Applications of isothermal titration calorimetry in pure and applied research from 2016 to 2020

The last 5 years have seen a series of advances in the application of isothermal titration microcalorimetry (ITC) and interpretation of ITC data. ITC has played an invaluable role in understanding multiprotein complex formation including proteolysis-targeting chimeras (PROTACS), and mitochondrial autophagy receptor Nix interaction with LC3 and GABARAP. It has also helped elucidate complex allosteric communication in protein complexes like trp RNA-binding attenuation protein (TRAP) complex. Advances in kinetics analysis have enabled the calculation of kinetic rate constants from pre-existing ITC data sets. Diverse strategies have also been developed to study enzyme kinetics and enzyme-inhibitor interactions. ITC has also been applied to study small molecule solvent and solute interactions involved in extraction, separation, and purification applications including liquid-liquid separation and extractive distillation. Diverse applications of ITC have been developed from the analysis of protein instability at different temperatures, determination of enzyme kinetics in suspensions of living cells to the adsorption of uremic toxins from aqueous streams