Expression profile of insulin 1 and insulin 2 (panels A and B, respectively) in the whole pancreas of cort+/+ and cort−/− male mice fed a low fat (LF) or high fat diet (HFD).

<p>C, plasma insulin level obtained from cort+/+ and cort−/− animals fed a LF- or HF-diet. Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cDNA obtained from 4–7 animals per experimental group. (*: p<0,05).</p

Expression level of different ghrelin system components in pancreatic islets of cort+/+ and cort−/− male mice fed a low fat (LF) or high fat diet (HFD).

<p>Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cDNA obtained from 4–7 animals per experimental group. (*:p<0,05; **: p<0,01; ***: p<0,001).</p

Expression level of different ghrelin system components in the whole pancreas of cort+/+ and cort−/− male mice fed a low fat (LF) or high fat diet (HFD).

<p>Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cDNA obtained from 3–7 animals per experimental group. (*: p<0,05; **: p<0,01; ***: p<0,001).</p

Evaluation of in vitro CORT action on glucose induced-Insulin release in cultured pancreatic islets from cort−/− mice.

<p>Values represent mean ± SEM obtained from 3 independent experiments. Different letters stand for statistical differences (p<0,05).</p

Expression profile of Insulin 1 and insulin 2 in pancreatic islets of cort+/+ and cort−/− male mice fed a low fat (LF) or high fat diet (HFD).

<p>Values represent mean ± SEM of copy number adjusted by β-actin expression per 100 ng of cDNA obtained from 2–3 animals per experimental group. (*: p<0,05).</p