’Antimicrobial Effects of Some Natural Dyes

The present study was taken up as an exploratory study to test if some natural dyes have inherent antimicrobial activity with a view to develop protective clothing from these. Twelve natural dyes Alchemilla vulgaris, Centaurium erythraea, Chamomillae vulgaris, Cortex juglandis, Flos tiliae argentum, Glycyrrhiza glabra, Lorthos tinctorius, Prunus avium, Salvia triloba, Fructus viburni opuli, Curcuma longa and Flos altheae were tested against common pathogen bacteria Escherichia coli ATCC 25922, Bacillus subtilis RSKK 244, Pseudomonas aureginosa ATCC 27853, Salmonella enteritidis ATCC 13076, Staphylococcus aureus ATCC 29213 and yeast Candida glabrata RSKK 04019, Candida albicans ATCC 90028. The results demonstrate that certain natural dyes are able to reduce microbial growth in the case of Bacillus subtilis, Escherichia coli and Staphylococcus aureus. Four of the natural dyes (obtained from Alchemilla vulgaris, Centaurium erythraea, Cortex juglandis, Flos althea) showed activity against one or more of the bacteria by disk diffusion method. Cortex juglandis dye was most effective against Staphylococcus aureus. The textile material impregnated with this natural dyes and maximum inhibition rate (88%). B. subtilis, E.coli and S.aureus of wool samples dyed with Centaurium erythraea and their inhibition rates (respectively, 11,14,23% ). Alchemilla vulgaris dye was effective against B.subtilis and S.aureus ( 24% and 14% ) while Flos altheae showed effect on E.coli ( 23% ).Key words : Antimicrobial activity, Natural dyes, textile

Momordica charantia Seed and Aryl Extracts Potentiate Growth Inhibition and Apoptosis by Dual Blocking of PI3K/AKT and MAPK Pathways as a Downstream Target of EGFR Signaling in Breast Cancer Cells

Background and Objective: Herbal extracts and plant compounds are increasingly becoming of interest for their therapeutic potential in various cancer types. Momordica charantia is well known for its anti-diabetic, anti-inflammatory, and anti-cancer properties