IC50 determination ixazomib [n = 2] for TOM-1 and BV-173.

Ph+ cells BV-173 and TOM-1 were treated with DMSO and bortezomib at day 0, CCK8 assay was performed at day 1,2 and 3. The IC50 is depicted in a non-linear regression curve with the point of inflections representing the respective IC50. The calculated IC50 values are shown in the table and ranged around 57nM for TOM-1 at d2 and 41.2nM for BV-173 at day 2. Errobars = SD, n = 2 for each treatment. (TIF)</p