3,423 research outputs found

    Steering a quantum system over a Schroedinger bridge

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    A new approach to the steering problem for quantum systems relying on Nelson's stochastic mechanics and on the theory of Schroedinger bridges is presented. The method is illustrated by working out a simple Gaussian example.Comment: Proc. Intern. Conf. on the Mathematical Theory of Networks and Systems, Perpignan, France, June 2000, CD-ROM, paper nr. 268, M. Fliess and A. El Jai Ed

    On the estimation of atmospheric turbulence layers for AO systems

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    In current and next generation of ground telescopes, Adaptive Optics (AO) are employed to overcome the detrimental effects induced by the presence of atmospheric turbulence, that strongly affects the quality of data transmission and therefore limits the actual resolution of the overall system. The analysis as well as the prediction of the turbulent phase affecting the light wavefront is therefore of paramount impor- tance to guarantee the effective performance of the AO solution. In this work, a layered model of turbulence is proposed, based on the definition of a Markov-Random-Field whose parameters are determined according to the turbulence statistics. The problem of turbulence estimation is formalized within the stochastic framework and conditions for the identifiability of the turbulence structure (numbers of layers, energies and velocities) are stated. Finally, an algorithm to allow the layer detection and characterization from measurements is designed. Numerical simulations are used to assess the proposed procedure and validate the results, confirming the validity of the approach and the accuracy of the detection

    Coefficient of thermal expansion of nanostructured tungsten based coatings assessed by thermally induced substrate curvature method

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    The in plane coefficient of thermal expansion (CTE) and the residual stress of nanostructured W based coatings are extensively investigated. The CTE and the residual stresses are derived by means of an optimized ad-hoc developed experimental setup based on the detection of the substrate curvature by a laser system. The nanostructured coatings are deposited by Pulsed Laser Deposition. Thanks to its versatility, nanocrystalline W metallic coatings, ultra-nano-crystalline pure W and W-Tantalum coatings and amorphous-like W coatings are obtained. The correlation between the nanostructure, the residual stress and the CTE of the coatings are thus elucidated. We find that all the samples show a compressive state of stress that decreases as the structure goes from columnar nanocrystalline to amorphous-like. The CTE of all the coatings is higher than the one of the corresponding bulk W form. In particular, as the grain size shrinks, the CTE increases from 5.1 106^{-6} K1^{-1} for nanocrystalline W to 6.6 106^{-6} K1^{-1} in the ultra-nano-crystalline region. When dealing with amorphous W, the further increase of the CTE is attributed to a higher porosity degree of the samples. The CTE trend is also investigated as function of materials stiffness. In this case, as W coatings become softer, the easier they thermally expand.Comment: The research leading to these results has also received funding from the European Research Council Consolidator Grant ENSURE (ERC-2014-CoG No. 647554

    Thermomechanical properties of amorphous metallic tungsten-oxygen and tungsten-oxide coatings

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    In this work, we investigate the correlation between morphology, composition, and the mechanical properties of metallic amorphous tungsten-oxygen and amorphous tungsten-oxide films deposited by Pulsed Laser Deposition. This correlation is investigated by the combined use of Brillouin Spectroscopy and the substrate curvature method. The stiffness of the films is strongly affected by both the oxygen content and the mass density. The elastic moduli show a decreasing trend as the mass density decreases and the oxygen-tungsten ratio increases. A plateaux region is detected in correspondence of the transition between metallic and oxide films. The compressive residual stresses, moderate stiffness and high local ductility that characterize compact amorphous tungsten-oxide films make them promising for applications involving thermal or mechanical loads. The coefficient of thermal expansion is quite high (i.e. 8.9 \cdot 106^{-6} K1^{-1}), being strictly correlated to the amorphous structure and stoichiometry of the films. Under thermal treatments they show a quite low relaxation temperature (i.e. 450 K). They crystallize into the γ\gamma monoclinic phase of WO3_3 starting from 670 K, inducing an increase by about 70\% of material stiffness.Comment: The research leading to these results has also received funding from the European Research Council Consolidator Grant ENSURE (ERC-2014-CoG No. 647554). The views and opinions expressed herein do not necessarily reflect those of the European Commissio

    Epilepsy, risks and insurance

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    Stroke epidemiology and COVID-19 pandemic

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    PURPOSE OF REVIEW: The aim of this study was to describe the impact of the COVID-19 outbreak on the epidemiology, cause and clinical characteristics of incident stroke in different settings and populations. RECENT FINDINGS: Several studies have shown that there are three main themes in the epidemiology of stroke during the COVID-19 pandemic: COVID-19 seems to be associated with stroke in a significant number of patients. This association has been reported in several clinical series, mainly from China. There is a consistent trend towards a decreased number of hospital admissions of stroke patients during the pandemic. There are no population-based data available on incident stroke in individuals with COVID-19. SUMMARY: In this review, we report on increased rates and severe prognosis of ischemic stroke among individuals with COVID-19, probably explained by hypercoagulability and inflammation, documented since the early phase of disease.We confirm the presence of falling rates of new ischemic stroke admissions in hospitals, probably due to social consequences of the pandemic: fear to be infected or not adequately treated in the hospital. This phenomenon is restricted to mild stroke and transient ischemic attacks.Short and long-term consequences of this trend of new strokes in the pandemic need to be evaluated

    Polymorphism rs7214723 in CAMKK1: a new genetic variant associated with cardiovascular diseases

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    Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide. CVDs have a complex etiology due to the several factors underlying its development including environment, lifestyle, and genetics. Given the role of calcium signal transduction in several CVDs, we investigated via PCR-restriction fragment length polymorphism (RFLP) the single nucleotide polymorphism (SNP) rs7214723 within the calcium/calmodulin-dependent kinase kinase 1 (CAMKK1) gene coding for the Ca2+/calmodulin-dependent protein kinase kinase I. The variant rs7214723 causes E375G substitution within the kinase domain of CAMKK1. A cross-sectional study was conducted on 300 cardiac patients. RFLP-PCR technique was applied, and statistical analysis was performed to evaluate genotypic and allelic frequencies and to identify an association between SNP and risk of developing specific CVD. Genotype and allele frequencies for rs7214723 were statistically different between cardiopathic and several European reference populations. A logistic regression analysis adjusted for gender, age, diabetes, hypertension, BMI and previous history of malignancy was applied on cardiopathic genotypic data and no association was found between rs7214723 polymorphism and risk of developing specific coronary artery disease (CAD) and aortic stenosis (AS). These results suggest the potential role of rs7214723 in CVD susceptibility as a possible genetic biomarker
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