PMH65 ADHERENCE AND PERSISTENCE TO TREATMENT IN PATIENTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; ANALYSES WITH THE RAMQ DATABASE

Specific cancer worry items, factor loadings, and Cronbach’s alpha for each sub scale. (DOC 36 kb

Large-scale diversity estimation through surname origin inference

The study of surnames as both linguistic and geographical markers of the past has proven valuable in several research fields spanning from biology and genetics to demography and social mobility. This article builds upon the existing literature to conceive and develop a surname origin classifier based on a data-driven typology. This enables us to explore a methodology to describe large-scale estimates of the relative diversity of social groups, especially when such data is scarcely available. We subsequently analyze the representativeness of surname origins for 15 socio-professional groups in France

Differences Between Students with and without Disabilities in College Counseling

This study examined differences between college students with and without disabilities who utilized college counseling center services. Although we found no differences between students with (n = 234, 9.2%) and without (n = 2,308, 90.8%) disabilities on number of counseling sessions attended, significant findings included: students with disabilities were more likely to self-terminate and more likely to be referred out than students without disabilities. Results suggest that students with disabilities are a diverse group requiring special consideration in college counseling settings. Recommendations for college counseling practice are discussed

Dimensionless Coupling of Bulk Scalars at the LHC

We identify the lowest-dimension interaction which is possible between Standard Model brane fields and bulk scalars in 6 dimensions. The lowest-dimension interaction is unique and involves a trilinear coupling between the Standard Model Higgs and the bulk scalar. Because this interaction has a dimensionless coupling, it depends only logarithmically on ultraviolet mass scales and heavy physics need not decouple from it. We compute its influence on Higgs physics at ATLAS and identify how large a coupling can be detected at the LHC. Besides providing a potentially interesting signal in Higgs searches, such couplings provide a major observational constraint on 6D large-extra-dimensional models with scalars in the bulk.Comment: 20 page

Murine Gammaherpesvirus 68 LANA Acts on Terminal Repeat DNA To Mediate Episome Persistence

Murine gammaherpesvirus 68 (MHV68) ORF73 (mLANA) has sequence homology to Kaposi’s sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA). LANA acts on the KSHV terminal repeat (TR) elements to mediate KSHV episome maintenance. Disruption of mLANA expression severely reduces the ability of MHV68 to establish latent infection in mice, consistent with the possibility that mLANA mediates episome persistence. Here we assess the roles of mLANA and MHV68 TR (mTR) elements in episome persistence. mTR-associated DNA persisted as an episome in latently MHV68-infected tumor cells, demonstrating that the mTR elements can serve as a cis-acting element for MHV68 episome maintenance. In some cases, both control vector and mTR-associated DNAs integrated into MHV68 episomal genomes. Therefore, we also assessed the roles of mTRs as well as mLANA in the absence of infection. DNA containing both mLANA and mTRs in cis persisted as an episome in murine A20 or MEF cells. In contrast, mTR DNA never persisted as an episome in the absence of mLANA. mLANA levels were increased when mLANA was expressed from its native promoters, and episome maintenance was more efficient with higher mLANA levels. Increased numbers of mTRs conferred more efficient episome maintenance, since DNA containing mLANA and eight mTR elements persisted more efficiently in A20 cells than did DNA with mLANA and two or four mTRs. Similar to KSHV LANA, mLANA broadly associated with mitotic chromosomes but relocalized to concentrated dots in the presence of episomes. Therefore, mLANA acts on mTR elements to mediate MHV68 episome persistence