9,909 research outputs found
A Modified Gravity and its Consequences for the Solar System, Astrophysics and Cosmology
A relativistic modified gravity (MOG) theory leads to a self-consistent,
stable gravity theory that can describe the solar system, galaxy and clusters
of galaxies data and cosmology.Comment: 16 pages. Latex file. Talk given at the International Workshop "From
Quantum to Cosmos: Fundamental Physics in Space", 22-24 May, 2006, Warrenton,
Virginia, USA. To be published in Int. J. Mod. Phys D. Equation correcte
Buckling instability in type-II superconductors with strong pinning
We predict a novel buckling instability in the critical state of thin type-II
superconductors with strong pinning. This elastic instability appears in high
perpendicular magnetic fields and may cause an almost periodic series of flux
jumps visible in the magnetization curve. As an illustration we apply the
obtained criteria to a long rectangular strip.Comment: Submitted to Phys. Rev. Let
The Adiabatic Instability on Cosmology's Dark Side
We consider theories with a nontrivial coupling between the matter and dark
energy sectors. We describe a small scale instability that can occur in such
models when the coupling is strong compared to gravity, generalizing and
correcting earlier treatments. The instability is characterized by a negative
sound speed squared of an effective coupled dark matter/dark energy fluid. Our
results are general, and applicable to a wide class of coupled models and
provide a powerful, redshift-dependent tool, complementary to other
constraints, with which to rule many of them out. A detailed analysis and
applications to a range of models are presented in a longer companion paper.Comment: 4 pages, 1 figur
A Simple Targeting Procedure for Lunar Trans-Earth Injection
A simple targeting algorithm for trans-Earth injection is developed. The techniques presented in this paper build on techniques developed for the Apollo program and other lunar and interplanetary missions. Presently, more sophisticated algorithms exist for solving this problem, but the simplicity of this particular algorithm makes it well-suited for on-board use during contingency and abort operations. In order to support a return from any lunar orbit with available fuel on the spacecraft the algorithm chooses between one-, two-, or three-burn return scenarios. The one- and two-burn cases are based on existing theory. For the three-burn case however, the existing theory is modified in order to provide a simple solution. Rather than attempting to create fuel-optimal trajectories, the algorithm presented in this paper focuses on computing a trajectory from low lunar orbit to direct atmospheric Earth entry that does not violate a fuel constraint. The algorithm attempts to use a minimal number of impulses to execute trans-earth injection. The algorithm can also be used to quickly generate good initial guesses for other more sophisticated targeting algorithms that can be used to find minimal fuel trajectories or optimize other parameters. This algorithm has three principle phases. First, an estimate of the hyperbolic excess velocity at the Lunar sphere of influence is generated. Second, a maneuver is computed that will transfer the craft from a lunar circular orbit to the hyperbolic escape asymptote. Finally, the effects of perturbations are eliminated by using linear state transition matrix targeting
Intra- and interobserver reproducibility of pelvic ultrasound for the detection and measurement of endometriotic lesions
STUDY QUESTION: What is the interobserver and intraobserver reproducibility of pelvic ultrasound for the detection of endometriotic lesions? SUMMARY ANSWER: Pelvic ultrasound is highly reproducible for the detection of pelvic endometriotic lesions. WHAT IS KNOWN ALREADY: Transvaginal ultrasound (TVS) has been widely adopted as the first-line assessment for the diagnosis and assessment of pelvic endometriosis. Severity of endometriosis as assessed by ultrasound has been shown to have good concordance with laparoscopy (kappa 0.79). The reproducibility of TVS for assessment of ovarian mobility and pouch of Douglas obliteration using the 'sliding sign' has already been described in the literature. However, there is no available data in the literature to demonstrate the intraobserver repeatability of measurements for endometriotic cysts and nodules. STUDY DESIGN SIZE DURATION: This was a prospective observational cross-sectional study conducted over a period of 12 months. We included 50 consecutive women who were all examined by two operators (A and B) during their clinic attendance. PARTICIPANTS/MATERIALS SETTING METHODS: The study was carried out in a specialist endometriosis centre. We included all consecutive women who had ultrasound scans performed independently by two experienced operators during the same visit to the clinic. The outcomes of interest were the inter- and intraobserver reproducibility for the detection of endometriotic lesions. We also assessed repeatability of the measurements of lesion size. MAIN RESULTS AND THE ROLE OF CHANCE: There was a good level of agreement between operator A and operator B in detecting the presence of pelvic endometriotic lesions (k = 0.72). There was a very good level of agreement between operators in identifying endometriotic cysts (k = 0.88) and a good level of agreement in identifying endometriotic nodules (k = 0.61). The inter- and intraobserver repeatability of measuring endometriotic cysts was excellent (intra-class correlation (ICC) ≥ 0.98). There was good interobserver measurement repeatability for bowel nodules (ICC 0.88), but the results for nodules in the posterior compartment were poor (ICC 0.41). The intraobserver repeatability for nodule size measurements was good for both operators (ICC ≥0.86). LIMITATIONS REASONS FOR CAUTION: Within this cohort, there was insufficient data to perform a separate analysis for nodule size in the anterior compartment. All examinations were performed within a specialised unit with a high prevalence of deep endometriosis. Our findings may not apply to operators without intensive ultrasound training in the diagnosis of pelvic endometriosis. WIDER IMPLICATIONS OF THE FINDINGS: These findings are important because ultrasound has been widely accepted as the first-line investigation for the diagnosis of pelvic endometriosis, which often determines the need for future investigations and treatment. The detection and measurement of bowel nodules is essential for anticipation of surgical risk and planning surgical excision. STUDY FUNDING/COMPETING INTERESTS: The authors have no conflict of interest. No funding was obtained for this work
Purification and characterization of a DNA helicase from Saccharomyces cerevisiae
A novel DNA helicase, scHelI, has been purified from whole cell extracts of Saccharomyces cerevisiae using biochemical assays to monitor the fractionation. The enzyme unwinds partial duplex DNA substrates, as long as 343 base pairs in length, in a reaction that is dependent on either ATP or dATP hydrolysis. scHelI also catalyzes a single-stranded DNA-dependent ATP hydrolysis reaction; the apparent Km for ATP is 325 microM. The unwinding reaction on circular partial duplex substrates is biphasic, with a fast component occurring within 5 min of the initiation of the reaction and a slow component continuing to 60 min. This is in contrast to the ATP hydrolysis reaction, which exhibits linear kinetics for 60 min. The direction of the unwinding reaction is 5' to 3' with respect to the strand of DNA on which the enzyme is bound. The unwinding reaction is strongly stimulated by the addition of Escherichia coli single-stranded DNA-binding protein when long partial duplex substrates are used. The enzymatic activity of scHelI copurifies with a polypeptide of 135 kDa as determined by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. The polypeptide sediments as a monomer in a glycerol gradient in the presence of 0.2 M NaCl
Magnetization Relaxation via Quantum and Classical Vortex Motion in a Bose Glass Superconductor
I show that in Bose Glass superconductor with high and at low the
magnetization relaxation (S), dominated by quantum tunneling, is , which crosses over to the conventional classical rate at
higher and lower , with the crossover . I argue
that due to interactions between flux lines there exist three relaxation
regimes, depending on whether ,
corresponding to Strongly-pinned Bose Glass (SBG) with large , Mott
Insulator (MI) with vanishing S, and Weakly-pinned Bose Glass (WBG)
characterized by small . I discuss the effects of interactions on
and focus attention on the recent experiment which is consistently described by
the theory.Comment: 4 pages, self-unpacking uuencoded compressed postscript file with
figures already inside text; to appear in Phys. Rev. Lett.(1995
Inter- and Intragranular Effects in Superconducting Compacted Platinum Powders
Compacted platinum powders exhibit a sharp onset of diamagnetic screening at
mK in zero magnetic field in all samples investigated. This
sharp onset is interpreted in terms of the intragranular transition into the
superconducting state. At lower temperatures, the magnetic ac susceptibility
strongly depends on the ac field amplitude and reflects the small intergranular
critical current density . This critical current density shows a strong
dependence on the packing fraction f of the granular samples. Surprisingly,
increases significantly with decreasing f ( A/cm for f = 0.67 and A/cm for f
= 0.50). The temperature dependence of shows strong positive curvature
over a wide temperature range for both samples. The phase diagrams of inter-
and intragranular superconductivity for different samples indicate that the
granular structure might play the key role for an understanding of the origin
of superconductivity in the platinum compacts.Comment: 11 pages including 9 figures. To appear in Phys. Rev. B in Nov. 0
Is the Universe Inflating? Dark Energy and the Future of the Universe
We consider the fate of the observable universe in the light of the discovery
of a dark energy component to the cosmic energy budget. We extend results for a
cosmological constant to a general dark energy component and examine the
constraints on phenomena that may prevent the eternal acceleration of our patch
of the universe. We find that the period of accelerated cosmic expansion has
not lasted long enough for observations to confirm that we are undergoing
inflation; such an observation will be possible when the dark energy density
has risen to between 90% and 95% of the critical. The best we can do is make
cosmological observations in order to verify the continued presence of dark
energy to some high redshift. Having done that, the only possibility that could
spoil the conclusion that we are inflating would be the existence of a
disturbance (the surface of a true vacuum bubble, for example) that is moving
toward us with sufficiently high velocity, but is too far away to be currently
observable. Such a disturbance would have to move toward us with speed greater
than about 0.8c in order to spoil the late-time inflation of our patch of the
universe and yet avoid being detectable.Comment: 7 pages, 7 figure
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