6 research outputs found
Effects of Feeding Polychlorinated Biphenyls to Broiler Cockerels in Three Dietary Regimes
Kidney disease of sheep, associated with infection by leptospires of the Sejroe serogroup
Switchgrass composition and yield response to alternative soil amendments under intensified heat and drought conditions
Structural Basis of Pattern Recognition by Innate Immune Molecules
The importance of the innate immune system as a first line defence against pathogenic challenge has long been recognised. Over the last decade the identity of many of the key molecules mediating innate host defence have been clarified and a model of self/nonself discrimination by families of pattern recognition receptors (PRRs) has emerged. Although a large amount of information is now available concerning the action of these innate immune molecules at the level of the cell and organism, little is known about the molecular interface between pathogens and innate immune recognition molecules. In this chapter the molecular basis for innate immune discrimination of a wide variety of pathogen derived molecules is discussed in the context of the emerging literature