40 research outputs found
Towards Atherosclerosis-on-a-Chip; A Microfluidic Platform for Anti-Atherosclerotic Drug Screening
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A Biomicrofluidic Screening Platform for Dysfunctional Endothelium‐Targeted Nanoparticles and Therapeutics
No full textA Biomicrofluidic Screening Platform for Dysfunctional Endothelium-Targeted Nanoparticles and Therapeutics
Get PDFCopyright © 2022 The Author(s) and Wiley-VCH GmbH. Biomicrofluidic Models Biomicrofluidic models allow nanoparticle-cellular interactions to be studied under physiological flow conditions. Investigating nanoparticle biophysicochemical properties in models that resemble disease can provide valuable information about the nano-bio interface. By screening nanoparticles dynamically against a developed dysfunctional-endothelium-on chip model, Nazila Kamaly and co-workers show in article number 2100092 that nanoparticle size is a dominant factor beyond targeting ligands. Furthermore, tight junction disruption can be restored by the inflammation resolving mediator Annexin A1.https://onlinelibrary.wiley.com/doi/10.1002/anbr.20227001
Effect of Nanoparticle Biophysicochemical Properties on Binding and Transport across Cardiovascular Endothelial Dysfunction Models
No full textDysfunctional Endothelium-on-a-chip, The Next Generation of Drugscreening Systems for Cardiovascular Disorders
No full textDevelopment of Polymeric Nanobiocatalysts for Diagnosis and Treatment of Atherosclerosis Disease
No full textPerformance of photopolymerized active layer forward osmosis membrane in the osmotic microbial fuel cell
No full textSimultaneous Cross-Linking and Cross-Polymerization of Enzyme Responsive Polyethylene Glycol Nanogels in Confined Aqueous Droplets for Reduction of Low-Density Lipoprotein Oxidation
No full textSynthesis of core-shell hybrid nanoparticles with pH responsive core and silica shell and their surface characterization
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