68 research outputs found
Cerebral Infarction Producing Sudden Isolated Foot Drop
Foot drop usually results from lesions affecting the peripheral neural pathway related to dorsiflexor muscles, especially the peroneal nerve. Although a central nervous system lesion is suspected when there is a lack of clinical evidence for a lower motor neuron lesion, such cases are extremely rare. We describe a patient with sudden isolated foot drop caused by a small acute cortical infarction in the high convexity of the precentral gyrus. This report indicates that a cortical infarction may have to be considered as a potential cause of foot drop
Primary spinal cord tumors of childhood: effects of clinical presentation, radiographic features, and pathology on survival
To determine the relationship between clinical presentation, radiographic features, pathology, and treatment on overall survival of newly diagnosed pediatric primary spinal cord tumors (PSCT). Retrospective analysis of all previously healthy children with newly diagnosed PSCT at a single institution from 1995 to present was performed. Twenty-five pediatric patients (15 boys, average 7.9Â years) were diagnosed with PSCT. Presenting symptoms ranged from 0.25 to 60Â months (average 7.8Â months). Symptom duration was significantly shorter for high grade tumors (average 1.65Â months) than low grade tumors (average 11.2Â months) (PÂ =Â 0.05). MRI revealed tumor (8 cervical, 17 thoracic, 7 lumbar, 7 sacral) volumes of 98â94,080Â mm3 (average 19,474Â mm3). Homogeneous gadolinium enhancement on MRI correlated with lower grade pathology (PÂ =Â 0.003). There was no correlation between tumor grade and volume (PÂ =Â 0.63) or edema (PÂ =Â 0.36) by MRI analysis. Median survival was 53Â months and was dependent on tumor grade (PÂ =Â 0.05) and gross total resection (PÂ =Â 0.01) but not on gender (PÂ =Â 0.49), age of presentation (PÂ =Â 0.82), duration of presenting symptoms (PÂ =Â 0.33), or adjuvant therapies (PÂ =Â 0.17). Stratified KaplanâMeier analysis confirmed the association between degree of resection and survival after controlling for tumor grade (PÂ =Â 0.01). MRI homogeneous gadolinium enhancement patterns may be helpful in distinguishing low grade from high grade spinal cord malignancies. While tumor grade and gross total resection rather than duration of symptoms correlated with survival in our series, greater than one-third of patients had reported symptoms greater than 6Â months duration prior to diagnosis
Neuroectodermal appendage: A case report and review
[No abstract available
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