MDCT Findings of Denim-Sandblasting-Induced Silicosis: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>Denim sandblasting is as a novel cause of silicosis in Turkey, with reports of a recent increase in cases and fatal outcomes. We aimed to describe the radiological features of patients exposed to silica during denim sandblasting and define factors related to the development of silicosis.</p> <p>Methods</p> <p>Sixty consecutive men with a history of exposure to silica during denim sandblasting were recruited. All CT examinations were performed using a 64-row multi-detector CT (MDCT). The nodules were qualitatively and semi-quantitatively analyzed by grading nodular profusion (NP) on CT images.</p> <p>Results</p> <p>Silicosis was diagnosed radiologically in 73.3% of patients (44 of 60). The latency period (the time between initial exposure and radiological imaging) and duration of silica exposure was longer in patients diagnosed with silicosis than in those without silicosis (p < 0.05). Nodules were present in all cases with centrilobular type as the commonest (63.6%). All cases of silicosis were clinically classified as accelerated and 11.4% had progressive massive fibrosis (PMF). Mild NP lesions were the most prevalent in all six zones of the lung. The NP score was significantly correlated with the duration of silica exposure, the latency period, presence of PMF, and pleural thickening. Enlarged lymphadenopathy was present in 45.5% of patients.</p> <p>Conclusions</p> <p>The duration of exposure and the latency period are important for development of silicosis in denim sandblasters. MDCT is a useful tool in detecting findings of silicosis in workers who has silica exposure.</p

Regression of Neointimal Hyperplasia of an Intracranial Stent: 6 Years Follow-up of A Wide-Necked Aneurysm

We present a case of wide-necked giant aneurysm located at the P1-P2 segment of the posterior cerebral artery. The initial goal for treatment of the aneurysm was hemodynamic flow redirection with subsequent thrombosis so the procedure and involved stent placement to the neck of the aneurysm without any filling material. During follow up, significant in-stent stenosis due to intimal hyperplasia was found at the 6th month on digital subtraction angiography. Regression of in-stent neointimal stenosis at the 18th month and a total disappearance at the 76th month were observed on follow-up angiograms. Illustrating the reversibility of neointimal hyperplasia during a long follow up period was the main goal of this case report