Anti-de Sitter boundary in Poincare coordinates

We study the space-time boundary of a Poincare patch of Anti-de Sitter (AdS) space. We map the Poincare AdS boundary to the global coordinate chart and show why this boundary is not equivalent to the global AdS boundary. The Poincare AdS boundary is shown to contain points of the bulk of the entire AdS space. The Euclidean AdS space is also discussed. In this case one can define a semi-global chart that divides the AdS space in the same way as the corresponding Euclidean Poincare chart.Comment: In this revised version we add a discussion of the physical consequences of the choice of a coordinate system for AdS space. We changed figure 1 and added more references. Version to be published in Gen. Relat. Grav

Pharmacologic concentrations of linezolid modify oxidative phosphorylation function and adipocyte secretome

The oxidative phosphorylation system is important for adipocyte differentiation. Therefore, xenobiotics inhibitors of the oxidative phosphorylation system could affect adipocyte differentiation and adipokine secretion. As adipokines impact the overall health status, these xenobiotics may have wide effects on human health. Some of these xenobiotics are widely used therapeutic drugs, such as ribosomal antibiotics. Because of its similarity to the bacterial one, mitochondrial translation system is an off-target for these compounds. To study the influence of the ribosomal antibiotic linezolid on adipokine production, we analyzed its effects on adipocyte secretome. Linezolid, at therapeutic concentrations, modifies the levels of apolipoprotein E and several adipokines and proteins related with the extracellular matrix. This antibiotic also alters the global methylation status of human adipose tissue-derived stem cells and, therefore, its effects are not limited to the exposure period. Besides their consequences on other tissues, xenobiotics acting on the adipocyte oxidative phosphorylation system alter apolipoprotein E and adipokine production, secondarily contributing to their systemic effects

Hawking-Page Phase Transition of black Dp-branes and R-charged black holes with an IR Cutoff

We show that the confinement-deconfinement phase transition of supersymmetric Yang-Mills theories with 16 supercharges in various dimensions can be realized through the Hawking-Page phase transition between the near horizon geometries of black Dp-branes and BPS Dp-branes by removing a small radius region in the geometry in order to realize a confinement phase, which generalizes the Herzog's discussion for the holographic hard-wall AdS/QCD model. Removing a small radius region in the gravitational dual corresponds to introducing an IR cutoff in the dual field theory. We also discuss the Hawking-Page phase transition between thermal $AdS_5$, $AdS_4$, $AdS_7$ spaces and R-charged AdS black holes coming from the spherical reduction of the decoupling limit of rotating D3-, M2-, and M5- branes in type IIB supergravity and 11 dimensional supergravity in grand canonical ensembles, where the IR cutoff also plays a crucial role in the existence of the phase transition.Comment: 34 pages, 18 figures, JHEP3, v2, references added, v3, some explanations adde

Shockwaves and deep inelastic scattering within the gauge/gravity duality

Within the gauge/gravity correspondence, we discuss the general formulation of the shockwave metric which is dual to a 'nucleus' described by the strongly-coupled N=4 SYM theory in the limit where the number of colors Nc is arbitrarily large. We emphasize that the 'nucleus' must possess Nc^2 degrees of freedom per unit volume, so like a finite-temperature plasma, in order for a supergravity description to exist. We critically reassess previous proposals for introducing transverse inhomogeneity in the shockwave and formulate a new proposal in that sense, which involves no external source but requires the introduction of an 'infrared' cutoff which mimics confinement. This cutoff however plays no role when the shockwave is probed by a highly virtual projectile, so like in deep inelastic scattering. We consider two such projectiles, the dilaton and the R-current, and compute the respective structure functions including unitarity corrections. We find that there are no leading-twist contributions to the structure functions at high virtuality, meaning that there are no point-like constituents in the strongly coupled 'nucleus'. In the black-disk regime at low virtuality, the structure functions are suggestive of parton saturation with occupation numbers of order one. The saturation momentum Qs grows with the energy like Qs^2 ~ 1/x (with x the Bjorken variable), which is the hallmark of graviton exchanges and is also necessary for the fulfillment of the energy-momentum sum rules.Comment: 43 page

Black-hole quasinormal modes and scalar glueballs in a finite-temperature AdS/QCD model

We use the holographic AdS/QCD soft-wall model to investigate the spectrum of scalar glueballs in a finite temperature plasma. In this model, glueballs are described by a massless scalar field in an AdS_5 black hole with a dilaton soft-wall background. Using AdS/CFT prescriptions, we compute the boundary retarded Green's function. The corresponding thermal spectral function shows quasiparticle peaks at low temperatures. We also compute the quasinormal modes of the scalar field in the soft-wall black hole geometry. The temperature and momentum dependences of these modes are analyzed. The positions and widths of the peaks of the spectral function are related to the frequencies of the quasinormal modes. Our numerical results are found employing the power series method and the computation of Breit-Wigner resonances.Comment: Revision: Results unchanged. More discussions on the model and on the results. References added. 28 pages, 7 figures, 5 table

Black Holes in Cascading Theories: Confinement/Deconfinement Transition and other Thermal Properties

We present numerical evidence for a transition between the Klebanov-Strassler background and a solution describing a black hole in the class of cascading solutions in the chirally restored phase. We also present a number of properties of this solution, including the running of the coupling constant, the viscosity to entropy ratio and the drag force on a quark moving in this background.Comment: 34 pages, 7 figures. Version to be published by JHE

Deep inelastic scattering of baryons in a modified soft wall model

We calculate the structure functions for unpolarized deep inelastic scattering of baryons using an AdS/QCD soft wall model that considers a dressed mass for the bulk fermionic fields. Considering the regime of large Bjorken parameter x, we compare the results for the proton structure function $F_2$ with experimental results.Comment: We improved the comparison with experimental data and included more references, version to appear in EPJ

Effectiveness of telephone monitoring in primary care to detect pneumonia and associated risk factors in patients with SARS-CoV-2

Improved technology facilitates the acceptance of telemedicine. The aim was to analyze the effectiveness of telephone follow-up to detect severe SARS-CoV-2 cases that progressed to pneumonia. A prospective cohort study with 2-week telephone follow-up was carried out March 1 to May 4, 2020, in a primary healthcare center in Barcelona. Individuals aged =15 years with symptoms of SARS-CoV-2 were included. Outpatients with non-severe disease were called on days 2, 4, 7, 10 and 14 after diagnosis; patients with risk factors for pneumonia received daily calls through day 5 and then the regularly scheduled calls. Patients hospitalized due to pneumonia received calls on days 1, 3, 7 and 14 post-discharge. Of the 453 included patients, 435 (96%) were first attended to at a primary healthcare center. The 14-day follow-up was completed in 430 patients (99%), with 1798 calls performed. Of the 99 cases of pneumonia detected (incidence rate 20.8%), one-third appeared 7 to 10 days after onset of SARS-CoV-2 symptoms. Ten deaths due to pneumonia were recorded. Telephone follow-up by a primary healthcare center was effective to detect SARS-CoV-2 pneumonias and to monitor related complications. Thus, telephone appointments between a patient and their health care practitioner benefit both health outcomes and convenience. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID-19 en establecimientos de atención de la salud Recomendaciones basadas en consenso de expertos e informadas en la evidencia

The “Asociación Colombiana de Infectología” (ACIN) and the “Instituto de Evaluación de Nuevas Tecnologías de la Salud” (IETS) created a task force to develop recommendations for Covid 19 health care diagnosis, management and treatment informed, and based, on evidence. Theses reccomendations are addressed to the health personnel on the Colombian context of health services. © 2020 Asociacion Colombiana de Infectologia. All rights reserved