Fertility Parameters in Crossbred Sows Treated with Cloprostenol Sodium (Synchromate®) in Zaria, Nigeria

This study was carried out to evaluate fertility parameters in crossbred sows in Zaria, following treatment with Cloprostenol sodium (Synchromate®). Ten (n = 10) apparently healthy crossbred sows were randomly assigned to two equal treatment groups based on number of injections of 500μg Synchromate®. Group 1 received two injections on days 0 and 13, while Group 2 received three injections on days 0, 7 and 13. Oestrus was monitored visually for signs of oestrus twice daily from 0700 – 1000h and 1500 – 1800h. The fertility parameters evaluated were: oestrus response rate (ORR), time to onset of oestrus (TOO), duration of oestrus (DOO), conception rate (CR), pregnancy rate (PR), farrowing rate (FR) and litter size (LS). Data on ORR, CR, PR and FR were expressed in percentages while TOO, DOO and LS were expressed as mean ± SEM. Student t-test and Tukey’s post-hoc test were used to compare the percentages and mean values between the groups. The Graphpad Prism® data package was used for statistical analysis and values of P<0.05 were considered significant. Fertility parameters TOO, DOO, LS, ORR, CR, PR, FR for Group 1 (187.20 ± 8.98h, 87.60 ± 4.49h, 7.25 ± 1.44, 100 %, 60 %, 80 % and 100 % respectively) and Group 2 (176.00 ± 40.00h, 86.60 ± 13.36h, 7.50 ± 1.50, 60 %, 100 %, 80 % and 66.67 % respectively). The differences in fertility parameters between the groups were not statistically significant. It is recommended therefore that double injections of cloprostenol sodium (Synchromate®) should be used for oestrus synchronization as it increases fertility parameters in cross bred sows at 13 days apart.Key words: Fertility parameters, crossbred sows, cloprostenol sodium, Zaria

Resolved Photon Processes

We review the present level of knowledge of the hadronic structure of the photon, as revealed in interactions involving quarks and gluons ``in" the photon. The concept of photon structure functions is introduced in the description of deep--inelastic $e \gamma$ scattering, and existing parametrizations of the parton densities in the photon are reviewed. We then turn to hard \gamp\ and \gaga\ collisions, where we treat the production of jets, heavy quarks, hard (direct) photons, \jpsi\ mesons, and lepton pairs. We also comment on issues that go beyond perturbation theory, including recent attempts at a comprehensive description of both hard and soft \gamp\ and \gaga\ interactions. We conclude with a list of open problems.Comment: LaTeX with equation.sty, 85 pages, 29 figures (not included). A complete PS file of the paper, including figures, can be obtained via anonymous ftp from ftp://phenom.physics.wisc.edu/pub/preprints/1995/madph-95-898.ps.

Higgs-Boson Production Induced by Bottom Quarks

Bottom quark-induced processes are responsible for a large fraction of the LHC discovery potential, in particular for supersymmetric Higgs bosons. Recently, the discrepancy between exclusive and inclusive Higgs boson production rates has been linked to the choice of an appropriate bottom factorization scale. We investigate the process kinematics at hadron colliders and show that it leads to a considerable decrease in the bottom factorization scale. This effect is the missing piece needed to understand the corresponding higher order results. Our results hold generally for charged and for neutral Higgs boson production at the LHC as well as at the Tevatron. The situation is different for single top quark production, where we find no sizeable suppression of the factorization scale. Turning the argument around, we can specify how large the collinear logarithms are, which can be resummed using the bottom parton picture.Comment: 18 page

Charged Higgs Boson Production in Bottom-Gluon Fusion

We compute the complete next-to-leading order SUSY-QCD corrections for the associated production of a charged Higgs boson with a top quark via bottom-gluon fusion. We investigate the applicability of the bottom parton description in detail. The higher order corrections can be split into real and virtual corrections for a general two Higgs doublet model and into additional massive supersymmetric loop contributions. We find that the perturbative behavior is well under control. The supersymmetric contributions consist of the universal bottom Yukawa coupling corrections and non-factorizable diagrams. Over most of the relevant supersymmetric parameter space the Yukawa coupling corrections are sizeable, while the remaining supersymmetric loop contributions are negligible.Comment: 18 pages, v2: some discussions added, v3: published versio

Higgs Physics at Future Colliders: recent theoretical developments

I review the physics of the Higgs sector in the Standard Model and its minimal supersymmetric extension, the MSSM. I will discuss the prospects for discovering the Higgs particles at the upgraded Tevatron, at the Large Hadron Collider, and at a future high--energy $e^+e^-$ linear collider with centre--of--mass energy in the 350--800 GeV range, as well as the possibilities for studying their fundamental properties. Some emphasis will be put on the theoretical developments which occurred in the last two years.Comment: 20 pages, latex, 12 figures. Talk given at PASCOS 2003 (Bombay, India

Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H

Mutations in two different domains of the ubiquitously expressed TRIM32 protein give rise to two clinically separate diseases, one of which is Limb-girdle muscular dystrophy type 2H (LGMD2H). Uncovering the muscle-specific role of TRIM32 in LGMD2H pathogenesis has proven difficult, as neurogenic phenotypes, independent of LGMD2H pathology, are present in TRIM32 KO mice. We previously established a platform to study LGMD2H pathogenesis using Drosophila melanogaster as a model. Here we show that LGMD2H disease-causing mutations in the NHL domain are molecularly and structurally conserved between fly and human TRIM32. Furthermore, transgenic expression of a subset of myopathic alleles (R394H, D487N, and 520fs) induce myofibril abnormalities, altered nuclear morphology, and reduced TRIM32 protein levels, mimicking phenotypes in patients afflicted with LGMD2H. Intriguingly, we also report for the first time that the protein levels of βPS integrin and sarcoglycan δ, both core components of costameres, are elevated in TRIM32 disease-causing alleles. Similarly, murine myoblasts overexpressing a catalytically inactive TRIM32 mutant aberrantly accumulate α- and β-dystroglycan and α-sarcoglycan. We speculate that the stoichiometric loss of costamere components disrupts costamere complexes to promote muscle degeneration

The Search for Higgs particles at high-energy colliders: Past, Present and Future

I briefly review the Higgs sector in the Standard Model and its minimal Supersymmetric extension, the MSSM. After summarizing the properties of the Higgs bosons and the present experimental constraints, I will discuss the prospects for discovering these particle at the upgraded Tevatron, the LHC and a high-energy $e^+e^-$ linear collider. The possibility of studying the properties of the Higgs particles will be then summarized.Comment: 28 pages, latex, 15 figures, talk at WHEPP VII, Allahabad, Indi