17 research outputs found
How do we estimate survival? External validation of a tool for survival estimation in patients with metastatic bone disease—decision analysis and comparison of three international patient populations
Survival, complications and outcome in 282 patients operated for neurological deficit due to thoracic or lumbar spinal metastases
Use of pedicle screw fixation in the management of malignant spinal disease: experience in 100 consecutive procedures
Comparative study of fibrous dysplasia and osteofibrous dysplasia: Histopathological, immunohistochemical, argyrophilic nucleolar organizer region and DNA ploidy analysis
Minimally invasive treatment of pathological fractures of the humeral shaft
Most patients with pathological fractures due to cancer metastasis have a limited life expectancy. Orthopaedic procedures, therefore, should be minimally invasive in order to avoid additional surgical morbidity. The purpose of this study was to analyse the results of minimally invasive approaches, including locked intramedullary nailing, followed by early postoperative radiation for pathological humeral shaft fractures. Twenty-four pathological fractures of the humerus diaphysis in 23 patients were treated with the prospective protocol, including antegrade unreamed intramedullary nailing and postoperative radiotherapy (20 Gy and five fractions). The patients and results of the surgery were evaluated by the Musculoskeletal Tumor Society upper extremity scoring system. All patients had a stable extremity, and the average function of 20 patients was 64% of the normal upper extremity function. Only one patient required revision surgery. The minimally invasive treatment of patients with pathological fractures of the humeral shaft with closed unreamed intramedullary nailing combined with adjuvant radiotherapy is an effective and safe procedure, even in seriously ill patients