10 research outputs found

    Self-Concept and Self-Esteem among Adults

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    Despite an ample study and analysis of Self concept and Self esteem, not a solitary deconstructive work has been done on the Effect of Self concept on Self esteem. So, this study aimed at the disclosure of all the ways through which self concept affects the self esteem among university students. The research method applied on the paper was quantitative. The study adopted a Multiple Self Concept Scale byBruce A. Bracken and Rosenberg’s Self- esteems scale (Rosenberg, 1965). The collected data analysis was accomplished statistically using the t-test and coefficient of correlation techniques. A sample of 250 students comprised of 75 males and 175 females was taken from BZU Multan. The inferences of the study conceded that Self Concept has a significant effect on Self esteem among university adults. Besides, the research inquiry brought the fact to light that there is, no doubt, a significant disparity of influences of self concept on self esteem between male and female

    Comparison of efficacy and safety of intramuscular magnesium sulphate with low dose intravenous regimen in treatment of eclampsia

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    INTRODUCTION: Eclampsia contributes to maternal mortality in developing, underdeveloped world. Various drugs have been tried to treat eclampsia. Magnesium sulphate has become the drug of choice due to various advantages and is associated with adverse outcome for both mother and fetus if not used correctly. OBJECTIVE: To compare the efficacy and safety of intramuscular magnesium sulphate with low dose intravenous regimen in treatment of eclampsia STUDY SETTING: The study was conducted at Gynecology and Obstetrics Department unit II, Holy Family Hospital, Rawalpindi, from June 20, 2020 to December 20, 2020. Study design was Randomized Controlled Trial. SUBJECTS & METHODS: Patients were randomly distributed into two groups, group-A (IM Group) and group-B (IV Group). Group-A patients received a loading dose of 4 gm IV MgSO4 over 5-10 minutes+10 gm MgSO4 deep intra-muscular injection (5 gm in each buttock) and a maintenance dose of 5 gm MgSO4 deep intramuscular injection in alternate buttock every 4 hourly. Group-B patients received MgSO4 4 gm slow IV over 5-10 minutes as loading dose and 1 gm MgSO4 per hour as continuous intravenous maintenance infusion. Clinical response to therapy for both drugs was calculated in terms of efficacy and safety. All the data were entered & analyzed by using SPSS v25.0. Both the groups were compared in terms of efficacy and safety by using Chi-Square test. A p-value less than 0.05  was taken as significant. RESULTS: A total of 160 patients with eclampsia were enrolled for this study. Patients were divided into two groups i.e. Group-A (IM MgSO4) and Group-B (IV MgSO4). In group-A, there were 45(56.3%) in 18-30 years age group and 35(43.8%) in 31-40 years age group, while in group-B, there were 48(60.0%) in 18-30 years age group and 32(40.0%) in 31-40 years age group. In IM MgSO4 group, prevention from recurrence of seizure was noted in 74(92.5%) and 78(97.5%) in IV MgSO4 group, which is statistically insignificant with a p-value of 0.147. CONCLUSION: Both IM and IV regimen are equally effective in controlling the recurrence of convulsions. IM Magnesium Sulphate is associated with a higher incidence of toxicity as evidenced by significantly higher incidence of loss of knee jerk reflex. Both IM and IV regimen are equally effective but IM Magnesium Sulphate is associated with a higher incidence of toxicity. KEY WORDS: Eclampsia, Intramuscular MgSO4, Intravenous MgSO4

    Hepatoprotective Effect of Berberis Lycium in Αlpha-Naphthylisothiocyanate Induced Cholestatic Mouse Models

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    Cholestasis is characterized by the obstruction of bile flow from hepatocytes to the intestine. It results in accumulation of bile acids in the liver, which cause oxidative stress, inflammation, apoptosis, fibrosis, and cirrhosis. Till now, the treatment options against cholestasis are limited. Therefore, there is an utmost requirement to develop and evaluate the drugs with potential anti-cholestatic effects. In the current study, the drug-induced cholestasis mouse models were generated via oral administration of α-naphthylisothiocyanate (ANIT). The mice were placed into three groups of six animals each. Group I was the control group and was given saline. The cholestasis model Group II was given saline for 19 days. On 19th day (48 hours before sacrifice) they received a single dose of ANIT (75 mg/kg). Group III served as the plant extract treatment group and received root extract for 19 days. On nineteenth day (48 hours before sacrifice) they received a single dose of ANIT (75 mg/kg). On 21st day, mice were sacrificed for analysis of serum biochemistry and liver histology. The results revealed that Berberis lycium extract has hepatoprotective properties, as serum level of AST (aspartate aminotransferase) and ALT (alanine transaminase) are significantly lower in the plant treatment group compared to the cholestasis model group. Furthermore, liver histology validated the serological results since the hepatocyte architecture in the plant treatment group was similar to that of control group. In conclusion, the data exhibit that B. lycium possess protective activities against ANIT induced cholestasis

    Financial Stress Cause Suicidal Ideation among the Lower Income Families; A Case Study of COVID-19 Period

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    During and after a pandemic, there is an upsurge in the number of people who commit suicide. COVID- There has been 19 recorded suicides in Pakistan. The number of deaths by suicide may be attributed to the current economic climate. Fear of infection is the second element that contributes to people committing suicide. The fact that a significant number of people are currently unemployed as a direct result of the closure contributes to the complexity of the situation. All of the suicides were carried out by males who were the primary breadwinners in their families. The judicial and legislative processes of Pakistan need to adopt a more scientific approach. According to a study that looked at cases of people who had attempted suicide, one of the most important contributing factors to the high rate of suicidal behavior among men is financial strain

    Comparing the Meaning Potential in Shakespeare and Manto through Speech Acts: A Discourse Pragmatic Study

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    This paper attempts to explain the application of speech act theory (John Searle, 1976) on the soliloquies expressed by Hamlet and Keshulal Singh. The descriptive focus of this study is to draw attention to the felicity conditions whether they are being fulfilled by the speakers while making an utterance or not. Content analysis based on speech act theory is used for this paper. It has been pointed out that declaratives are less while directives are more applicable on these soliloquies, with the help of analysis. Hamlet and Keshulal’s inner self is being depicted through their speeches and it is analyzed that they are so much upset and are in the situation of to be or not to be that they do not know what should be their strategies, in taking their revenge. In actuality, they are trying to extinguish the storm which is bursting inside them through their soliloquies but by comparing the inner devastation of both characters. It is highlighted that Hamlet’s soliloquies are more self-explanatory than that of Keshulal because Hamlet makes vows, questions, deplores, and challenges the circumstances more than the Keshulal

    Paramphistomum Cervi: Morphology, Life Cycle, Prevalence, Molecular Characterization, and Treatment Insights: A Comprehensive Review

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    Paramphistomum cervi, normally referred to as the rumen fluke or not unusual belly fluke, is a parasitic flatworm that infects the rumen and reticulum of ruminant animals worldwide. This overview article provides an outline of the superiority, molecular characterization, treatment, and manipulates measures associated with Paramphistomum cervi. The superiority of this parasite is enormous, affecting numerous domestic ruminants consist of sheep, farm animals, and goats. Recognising Paramphistomum cervi's molecular characteristics, such as its morphology, life cycle, and host interactions, is crucial for devising effective control strategies. Diagnostic techniques, including fecal examination and postmortem examination, are essential for accurate detection of Paramphistomum cervi infections. The article further explores the pathogenesis of this parasite, including the pathological changes it induces in affected animals' rumens and reticula. There is also discussion of the financial effects of Paramphistomum cervi infections on cattle productivity. Additionally, treatment options and anthelmintic drugs available for controlling Paramphistomum cervi infections are highlighted. The review concludes with an assessment of ongoing research. Overall, this review article provides a comprehensive analysis of Paramphistomum cervi, shedding light on its impact on animal health and providing valuable insights for the scientific and veterinary community

    Field surveys along habitat gradients revealed differences in herpetofauna assemblage in Margalla Hills National Park, Islamabad, Pakistan 

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    This study was conducted to see whether herpetofaunal assemblage differed amongst hiking trails, undisturbed forest and urban areas within the Margalla Hills National Park, Islamabad Capital Territory, Pakistan. Circular plot area-constrained searches (45 plots in each habitat, each plot with an area of 25 m2) were used from March 2018 to July 2019. We recorded seven amphibian species, nine lizard species and six snake species. The species richness of amphibians and lizards was the same in the studied strata, while the detection and encounter rate of snakes was lower in the undisturbed forest and urban areas. The encounter rate of amphibians differed significantly between urban areas and hiking trails/undisturbed forest. The encounter rate and population density of lizards differed significantly between undisturbed forest and urban areas. The most frequently encountered amphibian species along the hiking trail and urban areas was Duttaphrynus stomaticus, with Hoplobatrachus tigerinus in undisturbed forest. The most common and frequently encountered lizard species along the hiking trail and urban areas was Hemidactylus brookii, while the Ophisops jerdonii was the most frequently seen in undisturbed forest. The most common and frequently encountered snake species along the hiking trail and undisturbed forest was the Indotyphlops braminus, while Ptyas mucosa was the most common in urban areas. The subsequent bio-assessment, based on herpetofauna, of the Park revealed good to excellent biotic integrity The Park faces threats including livestock grazing, alien invasive vegetation and human disturbance due to settlements, restaurants and tourism-related activities. While several of these threats have been mitigated since the establishment of the Islamabad Wildlife Management Board, the Park still requires improved management, especially regarding regulating tourism

    Frequency of Diabetic and Non-diabetic patients having fetal anomalies at 3rd trimester using ultrasound

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    Background: Pre-gestational or gestational diabetes in pregnancy is now more common among pregnant mothers as a result of the obesity pandemic. Objective: To determine frequency of diabetic and non-diabetic patients having fetal anomalies at 3rd trimester using ultrasound. Methodology: Descriptive study was conducted at radiology department Chughtai Lab, Lahore. About 250 Diabetic and Non-Diabetic pregnant women of all age were included in this study. Consecutive sampling technique was used Data was analyzed by SSPS version 24.0. All quantitative variables were reported in mean ± S.D were presented in frequency and percentage and bar charts were presented. Results: The mean age of 250 participants was 28±5.1 with minimum age of 15 years and maximum age of 45 years. Out of 250 participants, 210(84%) had no Gestational Diabetes Mellitus and 40(16%) had Gestational Diabetes Mellitus. Out of 250 patients, 204(81.6%) had adequate Amniotic Fluid Index value, 27(10.8%) had Oligohydramnios and 19(7.6%) had Polyhydramnios. In our study 16(6.4%) diabetic patients and 26(10.4%) non-diabetic patients have anomalies. Conclusion: The study concluded that frequency of anomalies doesn’t depend on patients being diabetic or non-diabetic. As in our study diabetic patients are lesser anomalies than the non-diabetic patients. &nbsp
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