The VNTR polymorphism of the endothelial nitric oxide synthase gene and blood pressure in women at the end of pregnancy

Examine the association of the 4a/4b polymorphism of endothelial nitric oxide synthase (eNOS) with blood pressure in women at late pregnanc

Clinical and laboratory indicators in pregnant women with preeclampsia

The objective of this study is to compare clinical and laboratory indicators in pregnant women with preeclampsia (PE) compared with women with physiological pregnancy. The study group included 209 women with physiological pregnancy and 250 pregnant women with PE. We studied coagulogram data, biochemical blood analysis, and the level of systolic and diastolic blood pressure before and during pregnanc

Polymorphisms of genes and the risk of preeclampsia

They studied the relations of genetic polymorphisms with the risk of preeclampsia occurrence depending on hereditary complicatio

Genetic determinants of complicated pregnancy

The connections of polymorphic variants of the gene of vasoactive hormones with the level of arterial pressure in pregnant women, depending on the development of preeclampsia (PE), have been studie

Dataset of allele, genotype and haplotype frequencies of five polymorphisms CDKN2B-AS1 gene in Russian patients with primary open-angle glaucoma

Data on the allele, genotype and haplotype frequencies of the five single nucleotide polymorphisms (SNPs) such as rs1063192, rs7865618, rs2157719, rs944800 and rs4977756 of the CDKN2B-AS gene in Russian patients with primary open-angle glaucoma (POAG) are provide

Approaches to the construction of simulation model of the process optimization of rare plants microclonal propagation

The authors present approaches to constructing an imitation model for the optimization of the process of rare plants microclonal reproduction (on the example of the Belgorod region), which allow to identify the most effective ways of explants sterilization, to define the optimal composition of nutrient media for regenerants growth (tube plants) and growth regulators (phytohormones) for propagation of mini-plant

The study of the role of maternal and fetal risk factors in the development of placental insufficiency

The objectives were to study the role of maternal and fetal risk factors in the development of placental insufficiency (PI) and fetal growth retardation syndrome (FGRS

The effectiveness of glucocorticoid therapy in patients with chronic glomerulonephritis, depending on the polymorphic markers of cytokine genes

The paper presents the results of a study of interrelationships of polymorphic cytokine loci (rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1 and rs1800469 TGFβ-1) with the features of glucocorticoid therapy in patients with chronic glomerulonephriti

Breeding of Vicia faba L. in relation to drought resistance

The Yu.N. Kurkina field method was used to determine the drought tolerance of bean plants. An analysis of the totality of ecological and morphological traits of forage bean varieties of different origins revealed varieties with pronounced xeromorphicity with low plant heights and narrow leaves. The varieties with high drought resistance have been identifie

Low homology between 2019-nCoV Orf8 protein and its SARS-CoV counterparts questions their identical function

SARS-CoV accessory protein Orf8b is involved in suppressing interferon-mediated immune response of the infected cell and this might lead to supposition that the corresponding protein 2019-nCoV Orf8 shares the same role. But the tertiary structures of these proteins are still unknown, and the primary structures demonstrate very low homology and different calculating parameters. This time they both are affected by stabilizing selection and in natural viral populations do not tend to be deleted. The question whether in this case very different proteins could share the same function rises from the present dat