Laser-induced regeneration of cartilage

Laser radiation provides a means to control the fields of temperature and thermo mechanical stress, mass transfer, and modification of fine structure of the cartilage matrix. The aim of this outlook paper is to review physical and biological aspects of laser-induced regeneration of cartilage and to discuss the possibilities and prospects of its clinical applications. The problems and the pathways of tissue regeneration, the types and features of cartilage will be introduced first. Then we will review various actual and prospective approaches for cartilage repair; consider possible mechanisms of laser-induced regeneration. Finally, we present the results in laser regeneration of joints and spine disks cartilages and discuss some future applications of lasers in regenerative medicine. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE)

Possibility to study eta-mesic nuclei and photoproduction of slow eta-mesons at the GRAAL facility

A new experiment is proposed with the aim to study eta-mesic nuclei and low-energy interactions of eta with nuclei. Two decay modes of eta produced by a photon beam inside a nucleus will be observed, namely a collisional decay \eta N \to \pi N inside the nucleus and the radiative decay \eta \to \gamma \gamma outside. In addition, a collisional decay of stopped S_{11}(1535) resonance inside the nucleus, S_{11}(1535) N \to N N, will be studied. The experiment can be performed using the tagged photon beam at ESRF with the end-point energy 1000 MeV and the GRAAL detector which includes a high-resolution BGO calorimeter and a large acceptance lead-scintillator time-of-flight wall. Some results of simulation and estimates of yields are given.Comment: 20 pages, 19 figure

Measurement of Time Resolution of Scintillation Detectors with EQR-15 Silicon Photodetectors for the Time-of-Flight Neutron Detector of the BM@N Experiment

To study the dependence of the equation of state of high density nuclear matter on the term characterizing the isospin (proton-neutron) asymmetry of nuclear matter, it is necessary to measure azimuthal flow of neutrons as well as azimuthal flow of charged particles from a dense nuclear matter in the nuclear-nuclear collisions. For this purpose INR RAS is developing a new high-granular neutron detector which will be used in the BM@N experiment at the extracted beam of the Nuclotron accelerator at JINR (Dubna). This detector will identify neutrons and measure their energies in the heavy-ion collisions up to 4 GeV per nucleon. This article presents the results of measurements of the time resolution and light yields of samples of scintillation detectors with sizes 40$\times$40$\times$25 mm$^3$ that will be used in a neutron detector based on the currently available fast plastic scintillator manufactured by JINR using an EQR15 11-6060D-S photodetector for light readout. For comparison, the results of measurements for a detector of the same size with a fast scintillator EJ-230 and with the same type of photodetector are given. The measurements were made on cosmic muons as well as on the electron synchrotron "Pakhra" of the Lebedev Physical Institute of the Russian Academy of Sciences located in Troitsk, Moscow

Characteristics of the secondary electrons calibration beam of the accelerator S-25R "Pakhra"

The characteristics of the secondary electrons` calibration quasi-monochromatic beam of the accelerator S-25R "Pakhra" of the Lebedev Physical Institute of the Russian Academy of Sciences (LPI) on the basis of magnet SP-57 are presented. With an electron energy in the range of 45-280 MeV, a collimator diameter in front of the trigger counters of 3 mm and copper Converter thicknesses of 1-3 mm, the energy resolution and beam intensity were 4.4-2.2% and around 16 e/sec, respectively