Renal enlargement as primary presentation of acute lymphoblastic leukaemia

Renal enlargement in acute lymphoblastic leukaemia is well reported in literature from Western Countries. However there are very few reports from developing countries. Bilateral symmetrical enlargement of kidneys as a primary presentation of acute lymphoblastic leukaemia is rare. We report a child who had acute lymphoblastic leukaemia presenting with bilateral renal mass

Renal Enlargement as Primary Presentation of Acute Lymphoblastic Leukaemia

Renal enlargement in acute lymphoblastic leukaemia is well reported in literature from Western Countries. However there are very few reports from developing countries. Bilateral symmetrical enlargement of kidneys as a primary presentation of acute lymphoblastic leukaemia is rare. We report a child who had acute lymphoblastic leukaemia presenting with bilateral renal mass

The psychometric properties of Beck Depression Inventory for adolescent depression in a primary-care paediatric setting in India

Abstract Background There is increasing interest in identifying adolescents with depression in primary care settings by paediatricians in India. This article studied the diagnostic accuracy, reliability and validity of Beck Depression Inventory (BDI) while used by paediatricians in a primary care setting in India. Methods 181 adolescents attending 3 schools were administered a back translated Tamil version of BDI by a paediatrician to evaluate its psychometric properties along with Children's Depression Rating Scale (CDRS-R) for convergent validity. Clinical diagnosis of depressive disorders, for reference standard, was based on ICD-10 interview by an independent psychiatrist who also administered the Impact of Event Scale (IES) for divergent validity. Appropriate analyses for validity and diagnostic accuracy both at the item and scale levels were conducted. Results A cut-off score of ≥ 5 (Sn = 90.9%, Sp = 17.6 %) for screening and cut-off score of ≥ 22 (Sn = 27.3%, Sp = 90%) for diagnostic utility is suggested. The 4 week test – retest reliability was good (r = 0.82). In addition to the adequate face and content validity, BDI has very good internal consistency (α = 0.96), high convergent validity with CDRS-R (r = 0.72; P = 0.001), and high discriminant validity with IES (r = 0.26; P = 0.23). There was a moderate concordance rate with the reference standard (54.5%) in identifying depression among the adolescents. Factor analysis replicated the 2-factor structure explaining 30.5 % of variance. Conclusion The BDI proved to be a psychometrically sound measure for use by paediatricians in a primary care setting in India. The possibility of screening for depressive disorders through the use of BDI may be helpful in identifying probable cases of the disorder among adolescents.</p

A cross-sectional study on sleep among Indian adolescents

Background: Adolescent sleep deprivation affects their mental health, cardiovascular health, academic performance, and safety while on the road. This study analyzed sleep quality, hygiene, and daytime sleepiness among adolescents attending a tertiary care medical institution in Vellore. Materials and Methods: A school-based self-reported survey was conducted among 257 adolescents using the Adolescent Sleep–Wake Scale, Adolescent Sleep Hygiene Scale, and Epworth Sleepiness Scale. Unpaired t-test was used for continuous variables and Chi-square test for discrete variables for analysis. The correlation between sleep hygiene, sleep quality, and daytime sleepiness was done using Pearson correlation coefficient. Results: The mean age of participants was 14.5 ± 1.08 years. During weekdays, the mean bedtime was 9:39 pm ± 44 min and wake time 6:20 am ± 56 min. During weekends, the mean bedtime was 9:53 pm ± 49 min and wake time 7:03 am ± 88 min. The average duration of nighttime sleep was 8 h 40 min ± 64 min on weekdays and 9 h 10 min ± 81 min during weekends. Twelve percent experienced daytime sleepiness. There was a weak-to-moderate, inverse correlation of daytime sleepiness to sleep quality (r = −0.30) and sleep hygiene (r = −0.23). Mean scores of sleep quality and sleep hygiene were 4.25 and 4.29, respectively. There was a moderate-to-strong (r = 0.63) correlation with low scores in cognitive (mean = 3.72) and sleep stability domains (mean = 3.79). Conclusions: Adolescents in this study population have reasonably good sleep quality and hygiene. Sleep hygiene is closely related to sleep quality