Microwave-Assisted synthesis and evaluation of antibacterial activity of novel 6-fluoroaryl-[1,2,4]triazolo[1,5-A]pyrimidines

A series of 6-fluoroaryl substituted [1,2,4]triazolo[1,5-A]pyrimidines have been synthesized by using the microwave-Assisted Suzuki cross-coupling reaction from readily available 6-bromo-[1,2,4]triazolo[1,5-A]pyrimidine. The antimicrobial activity of new compounds has been evaluated in vitro against Mycobacterium tuberculosis H37Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria. © ARKAT-USA, Inc

Classical swine fever: retrospective analysis of epidemic situation in Russian Federation (1996-2015)

Progress trends in classical swine fever (CSF) epidemic situation in the Russian Federation in 1996-2015 are discussed in the paper. Spatial shift of CSF outbreaks from the central regions of the country (2007-2012) to the western and eastern border regions of the Russian Federation (2013-2015) has been confirmed. Based on the analysis, a short-term prognosis for 2016 has been made as well as recommendations on DIVA-based measures for CSF eradication in domestic pigs and wild boars in the RF have been provided

Application of parameters and requirements for the expert systems assessment in nano fiber based pharmaceutical technology

Todays, the most widely used category of intelligent systems are expert systems that are computer systems capable of partially replacing a highly trained professional in his/her area of expertise by means of information previously gained by the experts. That is why expert systems are agreed to be viewed along with information bases, which are models of the actions of experts in a particular area, and logical assumptions are extended to decision-making procedure

Characteristics of the epidemic process of chronic hepatitis b and its features in a large industrial center Central Urals.

The article deals with the results of a retrospective analysis of chronic hepatitis B in the city of Yekaterinburg in the period from 2013 to 2017 among different age groups and contingentsВ статье представлены результаты ретроспективного анализа заболеваемости хроническим гепатитом B на территории города Екатеринбурга в период с 2013г. по 2017 г. среди различных возрастных групп населения и контингентов

Porcine reproductoryand respiratory syndrome in the Russian Federation: control systems, risk identification

The paper deals with the issue of control strategies against porcine reproductory and respiratory syndrome in the Russian Federation. Biological and legal factors able to influence the quality of strategies applied in the RF are considered. It is recommended to develop a comprehensive approach to PRRS diagnostics, control and prevention for pig industry and update national PRRS legal and regulatory framework in the RF