Estimating the Concentration of Cadmium in the Qayyarah and Kasak Sites and its Impact on the Environment

Cadmium recorded a significant superiority in the soil of the Qayyarah site with a peak of (491.744) mg/kg compared to the Kasak site, which showed its highest concentration in the soil of (D1) at (0) metres. The highest value was recorded at (520.217) mg/kg, which indicates high pollution. Compared to the rest of the dimensions, the lowest concentration of cadmium was in the soil (D2) at a distance of (50) meters, amounting to (428,050) mg/kg. While we note that the Qayyarah site recorded the lowest values of cadmium at the distance (S2D2) (50 metres), with a concentration rate of (450.867) mg/kg. As for cadmium, its highest concentration was at the distance (S2D3) (100 metres) and (S2D5). It reached (521.867) mg/kg. While the Kasak site recorded the highest value of cadmium at a distance of (S1D1) (0 metres) with a concentration of (527.667) mg/kg, while the lowest concentration of cadmium was at point (S1D2) (50 metres) with a value of (405.233) mg/kg

Risk Factors for Breast Cancer in Gaza Strip, Palestine: a Case-Control Study

Breast cancer (BC) is the main common cause of cancer mortality among women in the world. This study aims at investigating BC epidemiology and identifying the different risk factors associated and the most affecting ones among women in the Gaza Strip, Palestine. This study was a hospital-based case-control (1: 2), as the study was carried out over the period of October 2014 to February 2015. A total of 105 BC patients, chosen from Al-Shifa Hospital in Gaza City and European hospital for the south governorate, were the case and compared to 209 women as a control group who matched the cases in age, residence, and with no history of breast problems. The age of the enrolled cases and controlled ranged between 18 to 60 years. The face-to-face interview was conducted during the patient visit to the oncology department and the control visit in their home. The result illustrated that women who had late pregnancy (> 35 years)(odds ratio [OR], 11.56; 95% confidence interval [CI], 1.64–81.35), or high body mass index (BMI;≥ 30 kg/m 2)(OR, 4.70; 95% CI, 1.62–13.69), or first-degree family history of BC (OR, 2.7; 95% CI, 1.04–7.20), or hypertensive patients (OR, 12.13; 95% CI, 1.93–76.10), or diabetic (OR, 6.84; 95% CI, 1.77–26.36) were more likely to have increased BC risk. The findings of the present study suggest that positive family history of BC, high BMI, and some common diseases (hypertension, diabetes mellitus) may be the epigenetic factors promoting the occurrence of BC

Efficacy and safety of the second in-hospital dose of tranexamic acid after receiving the prehospital dose: double-blind randomized controlled clinical trial in a level 1 trauma center

Background: Prehospital administration of tranexamic acid (TXA) to injured patients is increasing worldwide. However, optimal TXA dose and need of a second infusion on hospital arrival remain undetermined. We investigated the efficacy and safety of the second in-hospital dose of TXA in injured patients receiving 1 g of TXA in the prehospital setting. We hypothesized that a second in-hospital dose of TXA improves survival of trauma patients. Methods: A prospective, double-blind, placebo-controlled randomized, clinical trial included adult trauma patients receiving 1 g of TXA in the prehospital settings. Patients were then blindly randomized to Group I (second 1-g TXA) and Group II (placebo) on hospital arrival. The primary outcome was 24-h (early) and 28-day (late) mortality. Secondary outcomes were thromboembolic events, blood transfusions, hospital length of stay (HLOS) and organs failure (MOF). Results: A total of 220 patients were enrolled, 110 in each group. The TXA and placebo groups had a similar early [OR 1.000 (0.062–16.192); p = 0.47] and late mortality [OR 0.476 (95% CI 0.157–1.442), p = 0.18].The cause of death (n = 15) was traumatic brain injury (TBI) in 12 patients and MOF in 3 patients. The need for blood transfusions in the first 24 h, number of transfused blood units, HLOS, thromboembolic events and multiorgan failure were comparable in the TXA and placebo groups. In seriously injured patients (injury severity score > 24), the MTP activation was higher in the placebo group (31.3% vs 11.10%, p = 0.13), whereas pulmonary embolism (6.9% vs 2.9%, p = 0.44) and late mortality (27.6% vs 14.3%, p = 0.17) were higher in the TXA group but did not reach statistical significance. Conclusion: The second TXA dose did not change the mortality rate, need for blood transfusion, thromboembolic complications, organ failure and HLOS compared to a single prehospital dose and thus its routine administration should be revisited in larger and multicenter studies. Trial registration: ClinicalTrials.gov Identifier: NCT03846973

Dietary and Lifestyles assessment among Obese Women in Gaza City, Palestine

Background: The fundamental cause of obesity and overweight is an energy imbalance between calories consumed and calories expended. Aim: To clarify and figure out food habits and different lifestyle pattern among a sample of Palestinian women attending the nutrition center in the Gaza Strip. Methods: A cross-sectional study involved 116 women were randomly chosen by purposive census sampling. They aged 25 to 60 years with a diagnosis of obesity. The data collected by interview questionnaire that included social factors, lifestyle habits, and health/disease history. Results: Age group variable has distributed significantly (p=0.024), (31.0%) of morbid obese were ≥35 years group compared to (13.5%) of morbid obese amongst the younger group. The higher intakes of legumes (OR: 2.134, P=0.003), nuts (OR: 3.917, P=0.019), eggs (OR: 6.840, P=0.009), fast foods (OR: 4.461, P=0.005), and soda drinks (OR: 2.230, P=0.004) were the risk factors linked to the increased risk of morbid obesity. Moreover, the higher intakes of legumes (OR: 8.439, P=0.011), eggs (OR: 6.900, P=0.041), chips (OR: 5.049, P=0.012), sugar (OR: 2.068, P=0.011), and fast foods (OR: 3.029, P=0.025) are risk factors of chronic diseases. Conclusion: The study identified several lifestyle factors and improper dietary habits associated with obesity among women in Gaza city. There is a great need to change these habits to avoid the increased risk of obesity. Gene-environment interaction can explain the high incidence of obesity. A national plan of action to overcome obesity is urgently needed to reduce its economic and health burde

Epidemiology of acute diarrheal diseases among Children under five in Gaza Strip: Post war community based study

Diarrhoeal disease is the second leading cause of death in children under five years old, and is responsible for killing around 760 000 children every year. To study the determinants and the magnitude of acute diarrheal diseases one month after the cessation of the third Israeli aggression against Gaza Strip and to assess its burden among the children under five. This is cross sectional design study. Data has been collected throughout Gaza Strip. The sample size included 705 women from three governorates were surveyed out of five. Eligible women were interviewed using a pre designed, pre tested interview questionnaire. The period ( last month and the point ( 24 hours prevalence rates of diarrheal diseases among children under five years were 46.1% and 17.7% respectively. The Sex of the child had no significant effect on both point and period prevalence of diarrhea. More than sixty percent ( 63.3% of period prevalence of diarrhea was recorded among children that have no exclusive breastfeeding before. There are no significant differences for the point prevalence as a result of introducing the complementary feeding. Period and point prevalence rates of diarrhea were not significantly related to the room number. Both rates were higher for children in homes without refrigerators but only significant for point prevalence. It was found that 62.1% of the mother increased fluid intake, 54% of them used ORS. Drugs like anti diarrhea and herbal drugs were used by ( 61.4% and 40.3% respectively of the participating mothers. Cleaning of drinking water tanks and the domestic tanks have played a role in reducing the occurrence of diarrhea among children under five with highly statistically significant between both of them. It is concluded that there was high point and period prevalence of diarrhoea still exists among children in Gaza Strip. It is recommended to start to search for diarrhoea causes to reduce its incidence

Epidemiology of acute diarrheal diseases among Children under five in Gaza Strip: Post war community based study

Diarrhoeal disease is the second leading cause of death in children under five years old, and is responsible for killing around 760 000 children every year. To study the determinants and the magnitude of acute diarrheal diseases one month after the cessation of the third Israeli aggression against Gaza Strip and to assess its burden among the children under five. This is cross sectional design study. Data has been collected throughout Gaza Strip. The sample size included 705 women from three governorates were surveyed out of five. Eligible women were interviewed using a pre designed, pre tested interview questionnaire. The period (last month) and the point (24 hours) prevalence rates of diarrheal diseases among children under five years were 46.1% and 17.7% respectively. The Sex of the child had no significant effect on both point and period prevalence of diarrhea. More than sixty percent (63.3%) of period prevalence of diarrhea was recorded among children that have no exclusive breastfeeding before. There are no significant differences for the point prevalence as a result of introducing the complementary feeding. Period and point prevalence rates of diarrhea were not significantly related to the room number. Both rates were higher for children in homes without refrigerators but only significant for point prevalence. It was found that 62.1% of the mother increased fluid intake, 54% of them used ORS. Drugs like anti diarrhea and herbal drugs were used by (61.4% and 40.3%) respectively of the participating mothers. Cleaning of drinking water tanks and the domestic tanks have played a role in reducing the occurrence of diarrhea among children under five with highly statistically significant between both of them. It is concluded that there was high point and period prevalence of diarrhoea still exists among children in Gaza Strip. It is recommended to start to search for diarrhoea causes to reduce its incidence